Several Effector T Cell Functions Are Mediated by Cell Surface

Multiple Choice

Several effector T cell functions are mediated by cell surface molecules on the effector cell interacting with binding partners on the target cells. In the case of the CD40-CD40 ligand interaction, effector CD4 T cells express CD40 ligand, which binds to CD40 target cells. Individuals with a genetic deficiency in CD40 ligand expression show greatly reduced antibody responses, particularly to protein antigens which require CD4 T_FH cell interactions with B cells. Another expected defect in these individuals would be:

A) Reduced recruitment of eosinophils by T_H2 cells
B) Reduced recruitment of neutrophils by T_H17 cells
C) Reduced production of anti-microbial peptides induced by T_H17 cells
D) Reduced suppression of dendritic cells by T_reg cells
E) Reduced activation of macrophages by T_H1 cells