The Cellular Distribution of MHC Class I Versus MHC Class

Multiple Choice

The cellular distribution of MHC class I versus MHC class II molecules is quite different, with MHC class II molecules generally expressed on a very limited set of cell types. This is because:

A) It would be detrimental to have CD8 T cells killing macrophages or B cells.
B) CD4 T cells generally secrete cytokines that act on macrophages and B cells.
C) Viruses generally do not infect and replicate in macrophages and B cells.
D) Dendritic cells are more important in stimulating CD4 than CD8 T cell responses.
E) CD4 T cells can only kill macrophages, dendritic cells, and B cells.