Leucine Biosynthesis Occurs in a Multistep Pathway Starting from 2-Oxovalerate

Essay

Leucine biosynthesis occurs in a multistep pathway starting from 2-oxovalerate, and the final product of the pathway (leucine) inhibits the first enzyme involved in the biosynthetic pathway through a process called feedback inhibition. This enzyme inhibition occurs, regardless of whether or not the 2-oxovalerate substrate is bound in the active site of the enzyme. Describe what type of inhibitor leucine is and justify your response.