Exam 16: Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions

Draw the structure of the lactone product of the following reaction.

Consider the reaction below to answer the following question(s). -Refer to instructions. The purpose of the base catalyst in this reaction is:

Provide the missing structure(s) or reagent(s) for each reaction or sequences of reactions. Show all relevant stereochemistry. -Provide missing structure(s):

What is the order of decreasing reactivity towards nucleophilic acyl substitution for the carboxylic acid derivatives? (most reactive first)

Provide the missing structure(s) or reagent(s) for each reaction or sequences of reactions. Show all relevant stereochemistry. -Provide missing structure(s):

Consider the information below to answer the following question(s). The reaction of a carboxylic acid with an alcohol in the presence of acid is termed a Fischer esterification. -Refer to instructions. Compound C functions as _____ in this reaction.