Question 1

A natural killer lymphocyte detects the Fc region of an antibody bound to a cell and responds by releasing __________ and granzyme.

Accepted Answer

perforin

Question 2

The designation "B" for B lymphocytes comes from the

Accepted Answer

A)  fact that these cells produce antibodies. 
B)  bone marrow where these cells mature. 
C)  fact that these cells are most abundant in the blood.. 
D)  ability of these cells to provide immunity through bodily fluids. 
E)  sequence in which these lymphocytes where discovered. 
A)  fact that these cells produce antibodies. 
B)  bone marrow where these cells mature. 
C)  fact that these cells are most abundant in the blood.. 
D)  ability of these cells to provide immunity through bodily fluids. 
E)  sequence in which these lymphocytes where discovered. B

Question 3

Which of the following statements regarding antibody function is FALSE?

Accepted Answer

A)  They can prevent virus attachment to host cells. 
B)  They can facilitate phagocyte attack on bacteria with a capsule (glycocalyx). 
C)  They can penetrate host cells to bind intracellular antigens. 
D)  They can facilitate cytotoxic attack by natural killer lymphocytes. 
E)  They can bind more than one pathogen at a time, forming large aggregates. 
A)  They can prevent virus attachment to host cells. 
B)  They can facilitate phagocyte attack on bacteria with a capsule (glycocalyx). 
C)  They can penetrate host cells to bind intracellular antigens. 
D)  They can facilitate cytotoxic attack by natural killer lymphocytes. 
E)  They can bind more than one pathogen at a time, forming large aggregates. C

Question 4

Which of the following statements about lymphocytes is FALSE?

Accepted Answer

A)  Once they are mature, they migrate to secondary lymphoid organs. 
B)  B and T lymphocytes can be differentiated under the microscope. 
C)  Lymphocytes have integral surface glycoproteins by which they can be recognized. 
D)  The glycoproteins on the surface of a lymphocyte are designated with the prefix CD, for "cluster of differentiation." 
E)  Lymphocytes have different types of CD molecules in their cytoplasmic membranes. 
A)  Once they are mature, they migrate to secondary lymphoid organs. 
B)  B and T lymphocytes can be differentiated under the microscope. 
C)  Lymphocytes have integral surface glycoproteins by which they can be recognized. 
D)  The glycoproteins on the surface of a lymphocyte are designated with the prefix CD, for "cluster of differentiation." 
E)  Lymphocytes have different types of CD molecules in their cytoplasmic membranes.

Question 5

Which of the following is true of interferons?

Accepted Answer

A)  They are produced by virally infected cells. 
B)  They are involved in B lymphocyte activation and differentiation. 
C)  They are involved in chemotaxis of leukocytes. 
D)  They are substances used to signal between leukocytes. 
E)  They cause basophils and eosinophils to degranulate. 
A)  They are produced by virally infected cells. 
B)  They are involved in B lymphocyte activation and differentiation. 
C)  They are involved in chemotaxis of leukocytes. 
D)  They are substances used to signal between leukocytes. 
E)  They cause basophils and eosinophils to degranulate.

Question 6

Class II MHC (major histocompatibility antigens) are found on

Accepted Answer

A)  the skin. 
B)  red blood cells. 
C)  cytoplasmic membranes of nucleated cells. 
D)  muscle. 
E)  professional antigen-presenting cells. 
A)  the skin. 
B)  red blood cells. 
C)  cytoplasmic membranes of nucleated cells. 
D)  muscle. 
E)  professional antigen-presenting cells.

Question 7

You step on something in the yard and get a puncture wound that does not bleed freely. Antigens from any microbes that entered the wound will most likely end up in the

Accepted Answer

A)  appendix. 
B)  lymph nodes of the groin. 
C)  lymph nodes of the neck (cervical). 
D)  lymph nodes of the armpit (axilla). 
E)  spleen. 
A)  appendix. 
B)  lymph nodes of the groin. 
C)  lymph nodes of the neck (cervical). 
D)  lymph nodes of the armpit (axilla). 
E)  spleen.

Question 8

Compare and contrast clonal deletion and clonal selection of B lymphocytes.

Accepted Answer

Both clonal deletion and clonal selectio

Question 9

Cytokines are soluble regulatory proteins that act as intercellular signals and include substances such as interleukins, interferon, and growth factors.

Accepted Answer

A) True 
 B)False

Question 10

Which of the following function in agglutination?

Accepted Answer

A)  IgA antibodies 
B)  IgG antibodies 
C)  IgE antibodies 
D)  IgD antibodies 
E)  IgA and IgG antibodies 
A)  IgA antibodies 
B)  IgG antibodies 
C)  IgE antibodies 
D)  IgD antibodies 
E)  IgA and IgG antibodies

Question 11

Which of the following statements about helper T cells is FALSE?

Accepted Answer

A)  They secrete messenger proteins called cytokines. 
B)  They are sometimes called T4 cells. 
C)  There are two types: Th1 and Th2. 
D)  They cannot be distinguished from other T lymphocytes. 
E)  They function in conjunction with B cells. 
A)  They secrete messenger proteins called cytokines. 
B)  They are sometimes called T4 cells. 
C)  There are two types: Th1 and Th2. 
D)  They cannot be distinguished from other T lymphocytes. 
E)  They function in conjunction with B cells.

Question 12

Which of the following recognizes and binds to MHC II antigens and helps stabilize the binding of antigenic determinants to T cell receptors?

Accepted Answer

A)  CCR3 
B)  MHC I 
C)  CD26 
D)  CD4 
E)  CCR5 
A)  CCR3 
B)  MHC I 
C)  CD26 
D)  CD4 
E)  CCR5

Question 13

Describe the mechanisms of action of antibodies.

Accepted Answer

Antibodies act against foreign antigens

Question 14

Secretory IgA antibodies are unique because they

Accepted Answer

A)  have unique light chains. 
B)  are Y-shaped molecules. 
C)  are present in the plasma. 
D)  are connected with J chains and short polypeptides to form dimers. 
E)  are present in lymph nodes. 
A)  have unique light chains. 
B)  are Y-shaped molecules. 
C)  are present in the plasma. 
D)  are connected with J chains and short polypeptides to form dimers. 
E)  are present in lymph nodes.

Question 15

The protozoan that causes malaria is an intracellular parasite of red blood cells (RBCs). An adaptive immune response to this parasite is problematic because

Accepted Answer

A)  red blood cells do not produce MHC and therefore do not display the fact that they have been infected by presenting antigen. 
B)  the parasite damages leukocytes along with RBCs. 
C)  RBCs normally produce cytokines necessary for adaptive immune response, which this infection prevents. 
D)  complement cannot effectively destroy RBCs. 
E)  RBCs never enter lymphoid tissue. 
A)  red blood cells do not produce MHC and therefore do not display the fact that they have been infected by presenting antigen. 
B)  the parasite damages leukocytes along with RBCs. 
C)  RBCs normally produce cytokines necessary for adaptive immune response, which this infection prevents. 
D)  complement cannot effectively destroy RBCs. 
E)  RBCs never enter lymphoid tissue.

Question 16

IgG antibodies have a variety of mechanisms for acting on antigens.

Accepted Answer

A) True 
 B)False

Question 17

Which of the following molecules would contain T-independent antigens?

Accepted Answer

A)  phospholipids 
B)  lipoproteins 
C)  polysaccharides 
D)  glycoproteins 
E)  steroids 
A)  phospholipids 
B)  lipoproteins 
C)  polysaccharides 
D)  glycoproteins 
E)  steroids

Question 18

A single B lymphocyte can recognize multiple antigenic determinants.

Accepted Answer

A) True 
 B)False

Question 19

Which of the following statements concerning specific immunity is FALSE?

Accepted Answer

A)  It is the third line of defense. 
B)  It has memory. 
C)  It changes little with repeated exposure to the same pathogen. 
D)  It is acquired. 
E)  It is the body's ability to respond to specific invading pathogens. 
A)  It is the third line of defense. 
B)  It has memory. 
C)  It changes little with repeated exposure to the same pathogen. 
D)  It is acquired. 
E)  It is the body's ability to respond to specific invading pathogens.

Question 20

Which of the following statements concerning plasma cells is FALSE?

Accepted Answer

A)  They live a long time and function as memory cells. 
B)  They are activated B cells. 
C)  They produce 2000 antibodies per second. 
D)  They secrete antibody molecules with antigen-determining sites that act only against specific antigen determinants. 
E)  The antibodies they produce can remain in circulation for years. 
A)  They live a long time and function as memory cells. 
B)  They are activated B cells. 
C)  They produce 2000 antibodies per second. 
D)  They secrete antibody molecules with antigen-determining sites that act only against specific antigen determinants. 
E)  The antibodies they produce can remain in circulation for years.

Exam 16: Adaptive Immunity

A natural killer lymphocyte detects the Fc region of an antibody bound to a cell and responds by releasing __________ and granzyme.

The designation "B" for B lymphocytes comes from the

Which of the following statements regarding antibody function is FALSE?

Which of the following statements about lymphocytes is FALSE?

Which of the following is true of interferons?

Class II MHC (major histocompatibility antigens) are found on

You step on something in the yard and get a puncture wound that does not bleed freely. Antigens from any microbes that entered the wound will most likely end up in the

Compare and contrast clonal deletion and clonal selection of B lymphocytes.

Cytokines are soluble regulatory proteins that act as intercellular signals and include substances such as interleukins, interferon, and growth factors.

Which of the following function in agglutination?

Which of the following statements about helper T cells is FALSE?

Which of the following recognizes and binds to MHC II antigens and helps stabilize the binding of antigenic determinants to T cell receptors?

Describe the mechanisms of action of antibodies.

Secretory IgA antibodies are unique because they

The protozoan that causes malaria is an intracellular parasite of red blood cells (RBCs). An adaptive immune response to this parasite is problematic because

IgG antibodies have a variety of mechanisms for acting on antigens.

Which of the following molecules would contain T-independent antigens?

A single B lymphocyte can recognize multiple antigenic determinants.

Which of the following statements concerning specific immunity is FALSE?

Which of the following statements concerning plasma cells is FALSE?

A Brief History of Microbiology

The Chemistry of Microbiology

Cell Structure and Function

Microscopy, Staining, and Classification

Microbial Metabolism

Microbial Nutrition and Growth

Microbial Genetics

Recombinant Dna Technology

Controlling Microbial Growth in the Environment

Controlling Microbial Growth in the Body: Antimicrobial Drugs

Characterizing and Classifying Prokaryotes

Characterizing and Classifying Eukaryotes

Characterizing and Classifying Viruses, Viroids, and Prions

Infection, Infectious Diseases, and Epidemiology

Innate Immunity

Immunization and Immune Testing

Aids and Other Immune Disorders

Microbial Diseases of the Skin and Wounds

Microbial Diseases of the Nervous System and Eyes

Microbial Cardiovascular and Systemic Diseases

Microbial Diseases of the Respiratory System

Microbial Diseases of the Digestive System

Microbial Diseases of the Urinary and Reproductive Systems

Applied and Environmental Microbiology

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