Exam 30: Morphologic Analysis of Body Fluids in the Hematology

Which type of fluid is milky in appearance and is formed from long-standing effusions resulting from chronic conditions?

Cells found in fluids can be reactive mesothelial cells or malignant cells. Which features are found in reactive cells but not in malignant cells?

When evaluating a CSF for a hemorrhage or a traumatic tap, what laboratory results would be expected if it were a traumatic tap?

Interpret the following results: • Specimen: cerebrospinal fluid (CSF) • Tubes sent: 1-4 O Tube 1 RBC count: 30,000/mcL O Tube 2 RBC count: 1500/mcL O Tube 3 RBC count: 200/mcL O Tube 4 RBC count: 4/mcL • Gross examination: O Tube 1: moderate hemolysis, clear O Tube 2: slight hemolysis, clear O Tube 3: no hemolysis, clear O Tube 4: no hemolysis, clear • Xanthochromia: absent in all four tubes • Microscopic findings: O Many intact RBCs O 0-5 neutrophils O 0-5 lymphocytes O 0-5 MNCs What do these data most likely represent?

A crystal with long, thin, needlelike, pointed ends is identified in synovial fluid. The crystals are located inside and outside the cells. A quartz compensator is used, and it determines that the crystals are negatively birefringent and are a yellow color when parallel to the axis of the compensator. The crystal is blue when turned perpendicular to the axis of the compensator. What is the type of crystal?

A cell commonly seen in BAL specimens is the bronchial lining cell which can be distinguished by the presence of:

What morphological characteristics of the following cell types will help the technologist differentiate them? a. Mesothelial cells b. Adenocarcinoma c. Leukemic blasts d. Small-cell carcinoma

Which procedure is used to collect the pleural fluid from the pleural cavity?

Normal synovial fluid should have a total nucleated cell count of ________ with predominantly what type of cell?

What fluid is collected from the subarachnoid space?

Malignant tissue cells have which of the following morphologic features?

A patient with rheumatoid arthritis has fluid collected from his knee. The fluid has crystals that have a notched-plate shape. They are also birefringent. These crystals are most likely:

How would the technologist differentiate between a traumatic specimen collection tap and a cerebral hemorrhage? Provide at least three macroscopic and three microscopic findings.

Which of the following is responsible for producing cerebrospinal fluid?

Necrotic PMNs in a cytospin can be easily mistaken for which of the following?

An unknown cell in a body fluid possesses the following morphologic characteristics: 35 mcM in size, partially clumped chromatin, prominent nucleoli, jagged nuclear membrane, and clumped cell with nuclear molding. What is the most likely identification of the unknown cell?

The following results are obtained from a 38-year-old woman with congestive heart failure: • Specimen: pleural fluid • Fluid protein = 4.5 g/dl • Serum protein = 9.5 g/dl • Serum LD = 110 U/L • Fluid LD = 60 U/L These results are most consistent with which of the following?

A 3-year-old boy is admitted with febrile seizures. A lumbar puncture is performed to rule out meningitis. The cytospin differential shows many large lymphoblasts with irregular nuclear membranes. This means that the patient:

An unknown crystal exhibits positive birefringence. It is rhomboid in appearance. What is its most likely identification?

All of the following can be found in normal body fluid except: