Question 1

An example of artificial passive immunity would be

Accepted Answer

A)  chickenpox infection is followed by lifelong immunity. 
B)  chickenpox vaccine triggers extended immunity to chickenpox. 
C)  giving a person immune serum globulins to chickenpox virus after exposure to the disease. 
D)  a fetus acquiring maternal IgG to the chickenpox virus across the placenta. 
A)  chickenpox infection is followed by lifelong immunity. 
B)  chickenpox vaccine triggers extended immunity to chickenpox. 
C)  giving a person immune serum globulins to chickenpox virus after exposure to the disease. 
D)  a fetus acquiring maternal IgG to the chickenpox virus across the placenta. C

Question 2

The region of each antibody molecule where amino acid composition is very different from one clone of B lymphocytes to another is the

Accepted Answer

A)  variable region. 
B)  joining region. 
C)  constant region. 
D)  light region. 
E)  hinge region. 
A)  variable region. 
B)  joining region. 
C)  constant region. 
D)  light region. 
E)  hinge region. A

Question 3

Which is incorrect about the Fc region of an immunoglobulin?

Accepted Answer

A)  It determines the antibody's distribution in the body. 
B)  It forms the antigen binding sites. 
C)  It contains an effector molecule that can bind to cells such as macrophages and mast cells. 
D)  It contains an effector molecule that can fix complement. 
E)  It determines the class to which the immunoglobulin belongs. 
A)  It determines the antibody's distribution in the body. 
B)  It forms the antigen binding sites. 
C)  It contains an effector molecule that can bind to cells such as macrophages and mast cells. 
D)  It contains an effector molecule that can fix complement. 
E)  It determines the class to which the immunoglobulin belongs. B

Question 4

A hybridoma results from the fusion of a myeloma cell with a normal _____ cell.

Accepted Answer

The answer of A hybridoma results from the fusion of...

Question 5

Lymphocyte maturation involves

Accepted Answer

A)  hormonal signals that initiate development. 
B)  B-cells maturing in bone marrow sites. 
C)  T-cells maturing in the thymus. 
D)  release of mature lymphocytes to begin migration to various lymphoid organs. 
E)  All of these choices are correct. 
A)  hormonal signals that initiate development. 
B)  B-cells maturing in bone marrow sites. 
C)  T-cells maturing in the thymus. 
D)  release of mature lymphocytes to begin migration to various lymphoid organs. 
E)  All of these choices are correct.

Question 6

The most significant cells in graft rejection are

Accepted Answer

A)  helper T-cells. 
B)  suppressor T-cells. 
C)  cytotoxic T-cells. 
D)  B-cells. 
E)  natural killer NK) cells. 
A)  helper T-cells. 
B)  suppressor T-cells. 
C)  cytotoxic T-cells. 
D)  B-cells. 
E)  natural killer NK) cells.

Question 7

Antibody molecules circulate in lymph, blood, and tissue fluids.

Accepted Answer

A) True 
 B)False

Question 8

Antigen presenting cells

Accepted Answer

A)  include dendritic cells. 
B)  include macrophages. 
C)  engulf and modify antigen to be more immunogenic. 
D)  hold and present processed antigen on their cell membrane surface. 
E)  All of these choices are correct. 
A)  include dendritic cells. 
B)  include macrophages. 
C)  engulf and modify antigen to be more immunogenic. 
D)  hold and present processed antigen on their cell membrane surface. 
E)  All of these choices are correct.

Question 9

_____ is the most abundant class of antibodies in serum.

Accepted Answer

IgG; Immun

Question 10

Certain body sites contain sequestered molecules, called _____ that escaped assessment during development of immune tolerance and are mistaken as foreign.

Accepted Answer

The answer of Certain body sites contain sequestered molecules, called...

Question 11

Primary and secondary antibody response differ in all the following ways, except

Accepted Answer

A)  IgG production predominates in secondary responses. 
B)  the lag period between antigen stimulation and antibody response is shorter in the secondary response. 
C)  the rate of antibody production is faster in primary responses than in secondary responses. 
D)  primary responses are active whereas secondary responses are passive. 
A)  IgG production predominates in secondary responses. 
B)  the lag period between antigen stimulation and antibody response is shorter in the secondary response. 
C)  the rate of antibody production is faster in primary responses than in secondary responses. 
D)  primary responses are active whereas secondary responses are passive.

Question 12

Class II MHC genes code for

Accepted Answer

A)  certain secreted complement components. 
B)  self receptors recognized by natural killer cells. 
C)  all HLA antigens. 
D)  receptors located primarily on macrophages, dendritic cells, and B cells. 
E)  All of these choices are correct. 
A)  certain secreted complement components. 
B)  self receptors recognized by natural killer cells. 
C)  all HLA antigens. 
D)  receptors located primarily on macrophages, dendritic cells, and B cells. 
E)  All of these choices are correct.

Question 13

Properties of effective antigens include all the following, except

Accepted Answer

A)  foreign to the immune system. 
B)  molecular complexity. 
C)  large molecules with a minimum molecular weight of 1,000. 
D)  large polymers made up of identical repeating subunits. 
E)  cells or large, complex molecules. 
A)  foreign to the immune system. 
B)  molecular complexity. 
C)  large molecules with a minimum molecular weight of 1,000. 
D)  large polymers made up of identical repeating subunits. 
E)  cells or large, complex molecules.

Question 14

Which cells'direct involvement are required for cell-mediated immunity?

Accepted Answer

A)  T-cells 
B)  B-cells 
C)  bacterial cells 
D)  viral components 
E)  neutrophils 
A)  T-cells 
B)  B-cells 
C)  bacterial cells 
D)  viral components 
E)  neutrophils

Question 15

Class I MHC genes code for

Accepted Answer

A)  certain secreted complement components. 
B)  markers that display unique characteristics of self. 
C)  all HLA antigens. 
D)  receptors located primarily on macrophages and B cells. 
E)  All of these choices are correct. 
A)  certain secreted complement components. 
B)  markers that display unique characteristics of self. 
C)  all HLA antigens. 
D)  receptors located primarily on macrophages and B cells. 
E)  All of these choices are correct.

Question 16

Which process involves antibodies covering surface receptors on a virus or toxin molecule thereby disrupting their activity?

Accepted Answer

A)  neutralization 
B)  opsonization 
C)  complement fixation 
D)  agglutination 
E)  anamnestic response 
A)  neutralization 
B)  opsonization 
C)  complement fixation 
D)  agglutination 
E)  anamnestic response

Question 17

Which type of cell is severely depressed in AIDS patients?

Accepted Answer

A)  cytotoxic T-cells 
B)  helper T-cells 
C)  B-cells 
D)  pla cells 
E)  suppressor T-cells 
A)  cytotoxic T-cells 
B)  helper T-cells 
C)  B-cells 
D)  pla cells 
E)  suppressor T-cells

Question 18

All of the following are characteristics of an effective vaccine except

Accepted Answer

A)  it should have a relatively long shelf life. 
B)  it should stimulate only the antibody B-cell) response. 
C)  it should protect against wild forms of the pathogen. 
D)  it should not require numerous boosters. 
E)  it should be easy to administer. 
A)  it should have a relatively long shelf life. 
B)  it should stimulate only the antibody B-cell) response. 
C)  it should protect against wild forms of the pathogen. 
D)  it should not require numerous boosters. 
E)  it should be easy to administer.

Question 19

Which process involves antibodies cross-linking cells or particles into large aggregates?

Accepted Answer

A)  neutralization 
B)  opsonization 
C)  complement fixation 
D)  agglutination 
E)  anamnestic response 
A)  neutralization 
B)  opsonization 
C)  complement fixation 
D)  agglutination 
E)  anamnestic response

Question 20

Antitoxins

Accepted Answer

A)  contain antibodies to neutralize specific toxin. 
B)  use vaccinia virus with genetic material of bacterial toxins. 
C)  contain purified, chemically denatured bacterial exotoxin. 
D)  include capsule material against the pneumococcus and meningococcus. 
E)  contain attenuated organisms. 
A)  contain antibodies to neutralize specific toxin. 
B)  use vaccinia virus with genetic material of bacterial toxins. 
C)  contain purified, chemically denatured bacterial exotoxin. 
D)  include capsule material against the pneumococcus and meningococcus. 
E)  contain attenuated organisms.

Exam 15: Adaptive, Specific Immunity and Immunization

An example of artificial passive immunity would be

The region of each antibody molecule where amino acid composition is very different from one clone of B lymphocytes to another is the

Which is incorrect about the Fc region of an immunoglobulin?

A hybridoma results from the fusion of a myeloma cell with a normal _____ cell.

Lymphocyte maturation involves

The most significant cells in graft rejection are

Antibody molecules circulate in lymph, blood, and tissue fluids.

Antigen presenting cells

_____ is the most abundant class of antibodies in serum.

Certain body sites contain sequestered molecules, called _____ that escaped assessment during development of immune tolerance and are mistaken as foreign.

Primary and secondary antibody response differ in all the following ways, except

Class II MHC genes code for

Properties of effective antigens include all the following, except

Which cells'direct involvement are required for cell-mediated immunity?

Class I MHC genes code for

Which process involves antibodies covering surface receptors on a virus or toxin molecule thereby disrupting their activity?

Which type of cell is severely depressed in AIDS patients?

All of the following are characteristics of an effective vaccine except

Which process involves antibodies cross-linking cells or particles into large aggregates?

Antitoxins

The Main Themes of Microbiology

The Chemistry of Biology

Tools of the Laboratory: Methods of Studying Microorganisms

A Survey of Prokaryotic Cells and Microorganisms

A Survey of Eukaryotic Cells and Microorganisms

An Introduction to Viruses

Microbial Nutrition, Ecology, and Growth

An Introduction to Microbial Metabolism: the Chemical Crossroads of Life

Microbial Genetics

Genetic Engineering: a Revolution in Molecular Biology

Physical and Chemical Agents for Microbial Control

Drugs, Microbes, Host--The Elements of Chemotherapy

Microbe-Human Interactions: Infection and Disease

An Introduction to Host Defenses and Innate Immunities

Disorders in Immunity

Procedures for Identifying Pathogens and Diagnosing Infections

The Gram-Positive and Gram-Negative Cocci of Medical Importance

The Gram-Positive Bacilli of Medical Importance

The Gram-Negative Bacilli of Medical Importance

Miscellaneous Bacterial Agents of Disease

The Fungi of Medical Importance

The Parasites of Medical Importance

Introduction to Viruses That Infect Humans: the Dna Viruses

The Rna Viruses That Infect Humans

Environmental Microbiology

Applied and Industrial Microbiology

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