Question 1

In the primary response to an antigen, the first class of antibody to be secreted is

Accepted Answer

A)  IgD. 
B)  IgE. 
C)  IgG. 
D)  IgM. 
E)  IgA. 
A)  IgD. 
B)  IgE. 
C)  IgG. 
D)  IgM. 
E)  IgA.

Question 2

Which of the immunizations would carry the greatest risk for immunocompromised patients?

Accepted Answer

A)  killed, inactivated vaccines 
B)  attenuated vaccines 
C)  toxoids 
D)  immune serums 
E)  subunit vaccines 
A)  killed, inactivated vaccines 
B)  attenuated vaccines 
C)  toxoids 
D)  immune serums 
E)  subunit vaccines

Question 3

Human B lymphocytes mature in an intestinal region called the bursa.

Accepted Answer

A) True 
 B)False

Question 4

Post-exposure prophylaxis for rabies includes shots of HRIG human rabies immune globulin) and rabies vaccine. The HRIG provides ________________ whereas the vaccine promotes the development of _______________.

Accepted Answer

A)  artificial passive immunity; natural active immunity 
B)  artificial passive immunity; artificial active immunity 
C)  natural passive immunity; artificial passive immunity 
D)  artificial active immunity; artificial passive immunity 
E)  artificial active immunity; natural active immunity 
A)  artificial passive immunity; natural active immunity 
B)  artificial passive immunity; artificial active immunity 
C)  natural passive immunity; artificial passive immunity 
D)  artificial active immunity; artificial passive immunity 
E)  artificial active immunity; natural active immunity

Question 5

A disadvantage of using an attenuated live microbe in a vaccine is that it can conceivably mutate back to a virulent strain.

Accepted Answer

A) True 
 B)False

Question 6

The immunoglobulin class that is the only one capable of crossing the placenta is

Accepted Answer

A)  IgA. 
B)  IgD. 
C)  IgE. 
D)  IgG. 
E)  IgM. 
A)  IgA. 
B)  IgD. 
C)  IgE. 
D)  IgG. 
E)  IgM.

Question 7

Which antibody confers the most important specific local immunity to enteric, respiratory, and genitourinary pathogens?

Accepted Answer

A)  IgD 
B)  IgE 
C)  IgG 
D)  IgM 
E)  IgA 
A)  IgD 
B)  IgE 
C)  IgG 
D)  IgM 
E)  IgA

Question 8

Herceptin is an example of a monoclonal antibody-based drug for

Accepted Answer

A)  asthma. 
B)  crohn's disease. 
C)  breast cancer. 
D)  respiratory syncytial virus. 
E)  All of these choices are correct. 
A)  asthma. 
B)  crohn's disease. 
C)  breast cancer. 
D)  respiratory syncytial virus. 
E)  All of these choices are correct.

Question 9

Discuss, in detail, all the genetic and cellular events encompassed in the clonal selection theory of lymphocyte development.

Accepted Answer

The clonal selection theory of lymphocyt

Question 10

An example of natural passive immunity would be

Accepted Answer

A)  chickenpox infection is followed by lifelong immunity. 
B)  chickenpox vaccine triggers extended immunity to chickenpox. 
C)  giving a person immune serum globulins to chickenpox virus after exposure to the disease. 
D)  a fetus acquiring maternal IgG to the chickenpox virus across the placenta. 
A)  chickenpox infection is followed by lifelong immunity. 
B)  chickenpox vaccine triggers extended immunity to chickenpox. 
C)  giving a person immune serum globulins to chickenpox virus after exposure to the disease. 
D)  a fetus acquiring maternal IgG to the chickenpox virus across the placenta.

Question 11

Describe the characteristics that distinguish the following: a) antigen, b) hapten, c) antigenic determinant, d) alloantigen, e) heterophilic antigen, and f) autoantigen.

Accepted Answer

a) Antigen: An antigen is a substance th

Question 12

Natural killer NK) cells recognize and identify their targets in an immunologically nonspecific way, but then kill their targets in a manner very similar to that of TC cells.

Accepted Answer

A) True 
 B)False

Question 13

Reliable vaccines exist for all of the following diseases except

Accepted Answer

A)  malaria. 
B)  botulism. 
C)  cholera. 
D)  yellow fever. 
E)  rabies. 
A)  malaria. 
B)  botulism. 
C)  cholera. 
D)  yellow fever. 
E)  rabies.

Question 14

The process of clonal deletion is designed to

Accepted Answer

A)  destroy clones of lymphocytes able to react to self molecules. 
B)  slow down the primary immune response to an antigen. 
C)  slow down the secondary immune response to an antigen. 
D)  limit the number of lymphocyte clones an individual has in order to make the system more efficient. 
E)  slow down the immune system in the elderly. 
A)  destroy clones of lymphocytes able to react to self molecules. 
B)  slow down the primary immune response to an antigen. 
C)  slow down the secondary immune response to an antigen. 
D)  limit the number of lymphocyte clones an individual has in order to make the system more efficient. 
E)  slow down the immune system in the elderly.

Question 15

All of the following may be targeted by TC cells, except

Accepted Answer

A)  viral-infected host cells. 
B)  cancer cells. 
C)  invading bacterial cells. 
D)  cells in transplanted tissue from an imperfectly matched donor. 
E)  All of these cells could be targeted by Tc cells. 
A)  viral-infected host cells. 
B)  cancer cells. 
C)  invading bacterial cells. 
D)  cells in transplanted tissue from an imperfectly matched donor. 
E)  All of these cells could be targeted by Tc cells.

Question 16

Discuss the various ways by which antibodies interact with antigen and facilitate antigen inhibition or destruction.

Accepted Answer

Antibodies interact with antigens in var

Question 17

Helper T-cells

Accepted Answer

A)  secrete antibodies. 
B)  function in allergic reactions. 
C)  directly destroy target cells. 
D)  suppress immune reactions. 
E)  activate B-cells and other T-cells. 
A)  secrete antibodies. 
B)  function in allergic reactions. 
C)  directly destroy target cells. 
D)  suppress immune reactions. 
E)  activate B-cells and other T-cells.

Question 18

Which kind of T-cell synthesizes perforins and granzymes to destroy viral infected cells, and cancer cells?

Accepted Answer

A)  TC 
B)  TH 
C)  CD4 
D)  MHC 
A)  TC 
B)  TH 
C)  CD4 
D)  MHC

Question 19

Alloantigens are the basis for an individual's blood group and MHC profile.

Accepted Answer

A) True 
 B)False

Question 20

All of the following characterize the secondary response to an antigen except

Accepted Answer

A)  a higher titer of antibody is produced than the primary response. 
B)  a longer persistence of antibody than with the primary response. 
C)  a quicker rate of antibody synthesis than the primary response. 
D)  it is mostly IgM antibodies that are produced. 
E)  it is also known as the anamnestic response. 
A)  a higher titer of antibody is produced than the primary response. 
B)  a longer persistence of antibody than with the primary response. 
C)  a quicker rate of antibody synthesis than the primary response. 
D)  it is mostly IgM antibodies that are produced. 
E)  it is also known as the anamnestic response.

Exam 15: Adaptive, Specific Immunity and Immunization

In the primary response to an antigen, the first class of antibody to be secreted is

Which of the immunizations would carry the greatest risk for immunocompromised patients?

Human B lymphocytes mature in an intestinal region called the bursa.

Post-exposure prophylaxis for rabies includes shots of HRIG human rabies immune globulin) and rabies vaccine. The HRIG provides ________________ whereas the vaccine promotes the development of _______________.

A disadvantage of using an attenuated live microbe in a vaccine is that it can conceivably mutate back to a virulent strain.

The immunoglobulin class that is the only one capable of crossing the placenta is

Which antibody confers the most important specific local immunity to enteric, respiratory, and genitourinary pathogens?

Herceptin is an example of a monoclonal antibody-based drug for

Discuss, in detail, all the genetic and cellular events encompassed in the clonal selection theory of lymphocyte development.

An example of natural passive immunity would be

Describe the characteristics that distinguish the following: a) antigen, b) hapten, c) antigenic determinant, d) alloantigen, e) heterophilic antigen, and f) autoantigen.

Natural killer NK) cells recognize and identify their targets in an immunologically nonspecific way, but then kill their targets in a manner very similar to that of TC cells.

Reliable vaccines exist for all of the following diseases except

The process of clonal deletion is designed to

All of the following may be targeted by TC cells, except

Discuss the various ways by which antibodies interact with antigen and facilitate antigen inhibition or destruction.

Helper T-cells

Which kind of T-cell synthesizes perforins and granzymes to destroy viral infected cells, and cancer cells?

Alloantigens are the basis for an individual's blood group and MHC profile.

All of the following characterize the secondary response to an antigen except

The Main Themes of Microbiology

The Chemistry of Biology

Tools of the Laboratory: Methods of Studying Microorganisms

A Survey of Prokaryotic Cells and Microorganisms

A Survey of Eukaryotic Cells and Microorganisms

An Introduction to Viruses

Microbial Nutrition, Ecology, and Growth

An Introduction to Microbial Metabolism: the Chemical Crossroads of Life

Microbial Genetics

Genetic Engineering: a Revolution in Molecular Biology

Physical and Chemical Agents for Microbial Control

Drugs, Microbes, Host--The Elements of Chemotherapy

Microbe-Human Interactions: Infection and Disease

An Introduction to Host Defenses and Innate Immunities

Disorders in Immunity

Procedures for Identifying Pathogens and Diagnosing Infections

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The Fungi of Medical Importance

The Parasites of Medical Importance

Introduction to Viruses That Infect Humans: the Dna Viruses

The Rna Viruses That Infect Humans

Environmental Microbiology

Applied and Industrial Microbiology

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Post-exposure prophylaxis for rabies includes shots of HRIG human rabies immune globulin) and rabies vaccine. The HRIG provides __ whereas the vaccine promotes the development of _.

Natural killer NK) cells recognize and identify their targets in an immunologically nonspecific way, but then kill their targets in a manner very similar to that of T_C cells.

All of the following may be targeted by T_C cells, except