Question 1

The immunoglobulin class that has an Fc region that binds to receptors on basophils and mast cells is

Accepted Answer

A)  IgA. 
B)  IgD. 
C)  IgE. 
D)  IgG 
E)  IgM. 
A)  IgA. 
B)  IgD. 
C)  IgE. 
D)  IgG 
E)  IgM.

Question 2

In _____________ immunity, an individual makes their own antibodies in response to antigen exposure, whereas in _____________ immunity, an individual receives antibodies made by another individuals).

Accepted Answer

A)  artificial; active 
B)  active; passive 
C)  passive; active 
D)  natural; artificial 
E)  natural; active 
A)  artificial; active 
B)  active; passive 
C)  passive; active 
D)  natural; artificial 
E)  natural; active

Question 3

The albumin fraction of serum separated by electrophoresis will contain most of the antibodies.

Accepted Answer

A) True 
 B)False

Question 4

Describe the major histocompatability complex with regard to its: a) location, b) composition, c) relationship to specific cell markers, and d) role in regulation of immune reactions.

Accepted Answer

The major histocompatibility complex (MH

Question 5

Activation of B-cells occurs when antigen bonds to B-cell surface immunoglobulin receptors.

Accepted Answer

A) True 
 B)False

Question 6

The immunoglobulin/s found on the surface of B-cells is/are

Accepted Answer

A)  IgM only. 
B)  IgG only. 
C)  IgD only. 
D)  IgM and IgG. 
E)  IgE and IgA. 
A)  IgM only. 
B)  IgG only. 
C)  IgD only. 
D)  IgM and IgG. 
E)  IgE and IgA.

Question 7

Cytotoxic T-cells

Accepted Answer

A)  stimulate B-cell proliferation. 
B)  lack specificity for a target cell. 
C)  secrete granzymes and perforins that damage target cells. 
D)  secrete interleukin-2 to stimulate B and T-cells. 
E)  All of these choices are correct. 
A)  stimulate B-cell proliferation. 
B)  lack specificity for a target cell. 
C)  secrete granzymes and perforins that damage target cells. 
D)  secrete interleukin-2 to stimulate B and T-cells. 
E)  All of these choices are correct.

Question 8

Antigens that elicit allergic reactions are called _____.

Accepted Answer

The answer of Antigens that elicit allergic reactions are called...

Question 9

When antiserum is subjected to electrophoresis, the gamma globulin band contains mostly

Accepted Answer

A)  IgM. 
B)  IgA. 
C)  IgD. 
D)  IgE. 
E)  IgG. 
A)  IgM. 
B)  IgA. 
C)  IgD. 
D)  IgE. 
E)  IgG.

Question 10

An example of artificial active immunity would be

Accepted Answer

A)  chickenpox infection is followed by lifelong immunity. 
B)  chickenpox vaccine triggers extended immunity to chickenpox. 
C)  giving a person immune serum globulins to chickenpox virus after exposure to the disease. 
D)  a fetus acquiring maternal IgG to the chickenpox virus across the placenta. 
A)  chickenpox infection is followed by lifelong immunity. 
B)  chickenpox vaccine triggers extended immunity to chickenpox. 
C)  giving a person immune serum globulins to chickenpox virus after exposure to the disease. 
D)  a fetus acquiring maternal IgG to the chickenpox virus across the placenta.

Question 11

Scientists are currently developing bananas that synthesize proteins from pathogens, as a delivery system to vaccinate populations that otherwise would not have access to them.

Accepted Answer

A) True 
 B)False

Question 12

Which of the following conditions have been conclusively proven to be linked to childhood vaccinations?

Accepted Answer

A)  autism 
B)  diabetes 
C)  asthma 
D)  All of these choices are correct. 
A)  autism 
B)  diabetes 
C)  asthma 
D)  All of these choices are correct.

Question 13

The bone marrow is where

Accepted Answer

A)  immune responses to antigen occur. 
B)  blood stem cells give rise to immature lymphocytes. 
C)  antigen is filtered from the blood. 
D)  antigen is filtered from tissue fluid. 
E)  T-lymphocytes complete maturation. 
A)  immune responses to antigen occur. 
B)  blood stem cells give rise to immature lymphocytes. 
C)  antigen is filtered from the blood. 
D)  antigen is filtered from tissue fluid. 
E)  T-lymphocytes complete maturation.

Question 14

During presentation of APC-bound antigen, macrophages secrete a cytokine that activates T helper cells. What is the name of this cytokine?

Accepted Answer

A)  the major histocompatibility complex 
B)  interleukin-2 
C)  IgM 
D)  interleukin-1 
A)  the major histocompatibility complex 
B)  interleukin-2 
C)  IgM 
D)  interleukin-1

Question 15

Acellular vaccines and subunit vaccines

Accepted Answer

A)  contain modified bacterial exotoxin molecules. 
B)  are always genetically engineered. 
C)  contain select antigenic components of a pathogen rather than whole cells or viruses. 
D)  confer passive immunity. 
E)  All of these choices are correct. 
A)  contain modified bacterial exotoxin molecules. 
B)  are always genetically engineered. 
C)  contain select antigenic components of a pathogen rather than whole cells or viruses. 
D)  confer passive immunity. 
E)  All of these choices are correct.

Question 16

Which part of an antibody molecule contains the variable regions of a heavy and light chain that fold into a groove that will interact directly with and bind to a specific antigen?

Accepted Answer

A)  Fc end 
B)  Fab ends 
C)  heavy chains 
D)  light chains 
E)  disulfide bonds 
A)  Fc end 
B)  Fab ends 
C)  heavy chains 
D)  light chains 
E)  disulfide bonds

Question 17

T-cell response to T-cell-dependent antigens requires

Accepted Answer

A)  typically a protein antigen. 
B)  binding of T-cell to a Class II MHC receptor on an antigen-presenting cell. 
C)  binding of T-cell to a site on the antigen. 
D)  interleukin-1 activating the T helper cell. 
E)  All of these choices are correct. 
A)  typically a protein antigen. 
B)  binding of T-cell to a Class II MHC receptor on an antigen-presenting cell. 
C)  binding of T-cell to a site on the antigen. 
D)  interleukin-1 activating the T helper cell. 
E)  All of these choices are correct.

Question 18

High titers of specific antibodies are components of

Accepted Answer

A)  specific immune globulin SIG). 
B)  gamma globulin. 
C)  immune serum globulin ISG). 
D)  attenuated vaccines. 
E)  toxoids. 
A)  specific immune globulin SIG). 
B)  gamma globulin. 
C)  immune serum globulin ISG). 
D)  attenuated vaccines. 
E)  toxoids.

Question 19

Which of the following is a special binding substance that enhances immugenicity and prolongs antigen retention at the injection site?

Accepted Answer

A)  adjuvant 
B)  booster 
C)  antibodies to toxin 
D)  gamma globulin 
E)  "Trojan horse" recombinant vaccine 
A)  adjuvant 
B)  booster 
C)  antibodies to toxin 
D)  gamma globulin 
E)  "Trojan horse" recombinant vaccine

Question 20

The major histocompatability complex is

Accepted Answer

A)  a group of blood vessels that protects the nervous system. 
B)  a set of genes that code for MHC cell receptors. 
C)  also known as the complement system. 
D)  located in the thymus gland. 
E)  All of these choices are correct. 
A)  a group of blood vessels that protects the nervous system. 
B)  a set of genes that code for MHC cell receptors. 
C)  also known as the complement system. 
D)  located in the thymus gland. 
E)  All of these choices are correct.

Exam 15: Adaptive, Specific Immunity and Immunization

The immunoglobulin class that has an Fc region that binds to receptors on basophils and mast cells is

In _____________ immunity, an individual makes their own antibodies in response to antigen exposure, whereas in _____________ immunity, an individual receives antibodies made by another individuals).

The albumin fraction of serum separated by electrophoresis will contain most of the antibodies.

Describe the major histocompatability complex with regard to its: a) location, b) composition, c) relationship to specific cell markers, and d) role in regulation of immune reactions.

Activation of B-cells occurs when antigen bonds to B-cell surface immunoglobulin receptors.

The immunoglobulin/s found on the surface of B-cells is/are

Cytotoxic T-cells

Antigens that elicit allergic reactions are called _____.

When antiserum is subjected to electrophoresis, the gamma globulin band contains mostly

An example of artificial active immunity would be

Scientists are currently developing bananas that synthesize proteins from pathogens, as a delivery system to vaccinate populations that otherwise would not have access to them.

Which of the following conditions have been conclusively proven to be linked to childhood vaccinations?

The bone marrow is where

During presentation of APC-bound antigen, macrophages secrete a cytokine that activates T helper cells. What is the name of this cytokine?

Acellular vaccines and subunit vaccines

Which part of an antibody molecule contains the variable regions of a heavy and light chain that fold into a groove that will interact directly with and bind to a specific antigen?

T-cell response to T-cell-dependent antigens requires

High titers of specific antibodies are components of

Which of the following is a special binding substance that enhances immugenicity and prolongs antigen retention at the injection site?

The major histocompatability complex is

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Filters

In _ immunity, an individual makes their own antibodies in response to antigen exposure, whereas in _ immunity, an individual receives antibodies made by another individuals).