Question 1

What is the major organic product of the following sequence of reactions?

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  4 
A)  1 
B)  2 
C)  3 
D)  4

Question 2

The reaction of a(n) _____ with an alcohol cannot be used to prepare an ester.

Accepted Answer

A)  acid halide 
B)  carboxylic acid 
C)  acid anhydride 
D)  amide 
A)  acid halide 
B)  carboxylic acid 
C)  acid anhydride 
D)  amide

Question 3

What is the major organic product obtained from the following reaction?

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  4 
A)  1 
B)  2 
C)  3 
D)  4

Question 4

What is "X" in the following reaction? ​

Accepted Answer

A) 
  
B) 
  
C) 
  
D) 
  
A) 
  
B) 
  
C) 
  
D)

Question 5

Which of the following is the correct order of decreasing reactivity in hydrolysis reactions (more reactive > less reactive)?

Accepted Answer

A)  anhydrides > amides > acid chlorides 
B)  amides > acid chlorides > anhydrides 
C)  anhydrides > acid chlorides > amides 
D)  acid chlorides > anhydrides > amides 
A)  anhydrides > amides > acid chlorides 
B)  amides > acid chlorides > anhydrides 
C)  anhydrides > acid chlorides > amides 
D)  acid chlorides > anhydrides > amides

Question 6

What is the major organic product obtained from the following reaction?

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  4 
A)  1 
B)  2 
C)  3 
D)  4

Question 7

Esters react with alcohols in an acid-catalyzed reaction called _____. ​

Accepted Answer

A)  combustion 
B)  esterification 
C)  transesterification 
D)  rearrangement 
A)  combustion 
B)  esterification 
C)  transesterification 
D)  rearrangement

Question 8

Which of the following is the correct order of decreasing leaving group ability in nucleophilic acyl substitutions (better leaving group > worse leaving group)?

Accepted Answer

A)  Cl− > CH3COO− > CH3O− 
B)  CH3COO− > CH3O− > Cl− 
C)  Cl−> CH3O− > CH3COO− 
D)  CH3O− > Cl− > CH3COO− 
A)  Cl− > CH3COO− > CH3O− 
B)  CH3COO− > CH3O− > Cl− 
C)  Cl−> CH3O− > CH3COO− 
D)  CH3O− > Cl− > CH3COO−

Question 9

Which of the following statements is not true in relation to the hydrolysis of esters?

Accepted Answer

A)  Hydrolysis of esters under acid conditions requires only a catalytic amount of a strong acid 
B)  Hydrolysis of esters under basic conditions requires a stoichiometric amount of hydroxide 
C)  Under acidic conditions for hydrolysis of esters protonation of the ester increases its electrophilicity 
D)  Under basic conditions for hydrolysis of esters deprotonation of the ester increases its nucleophilicity 
A)  Hydrolysis of esters under acid conditions requires only a catalytic amount of a strong acid 
B)  Hydrolysis of esters under basic conditions requires a stoichiometric amount of hydroxide 
C)  Under acidic conditions for hydrolysis of esters protonation of the ester increases its electrophilicity 
D)  Under basic conditions for hydrolysis of esters deprotonation of the ester increases its nucleophilicity

Question 10

What is the major organic product obtained from the following reaction?

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  4 
A)  1 
B)  2 
C)  3 
D)  4

Question 11

_____ do not react with ammonia, primary amines, and secondary amines.

Accepted Answer

A)  Acid halides 
B)  Esters 
C)  Acid anhydrides 
D)  Amides 
A)  Acid halides 
B)  Esters 
C)  Acid anhydrides 
D)  Amides

Question 12

Which of the following is the correct order of decreasing acid strength of the following compounds (more acidic > less acidic)?

Accepted Answer

A)  1 > 2 > 3 
B)  2 > 3 > 1 
C)  1 > 3 > 2 
D)  3 > 2 > 1 
A)  1 > 2 > 3 
B)  2 > 3 > 1 
C)  1 > 3 > 2 
D)  3 > 2 > 1

Question 13

What is the IUPAC name of the following compound?

Accepted Answer

(Z)-ethyl

Question 14

What is the major organic product obtained from the following reaction?

Accepted Answer

The answer of What is the major organic product obtained...

Question 15

What two organic compounds are obtained from the following reaction?

Accepted Answer

The answer of What two organic compounds are obtained from...

Question 16

What is the major organic product obtained from the following reaction?

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  4 
A)  1 
B)  2 
C)  3 
D)  4

Question 17

Consider the isotopically tagged substance below.   Saponification of this substance will produce the following products.  $+ \quad\mathrm{CH}_{3} \mathrm{CH}_{2} \mathrm{CH}_{2} \mathrm{OH}$

Accepted Answer

A) True 
 B)False

Question 18

Consider the following 1H NMR spectrum.   The line indicated with the number _____ would indicate the presence of a C=O group.

Accepted Answer

Question 19

What is the major organic product obtained from the following reaction?

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  4 
A)  1 
B)  2 
C)  3 
D)  4

Question 20

What is the major organic product obtained from the following reaction?

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  4 
A)  1 
B)  2 
C)  3 
D)  4

Exam 18: Functional Derivatives of Carboxylic Acids

What is the major organic product of the following sequence of reactions?

The reaction of a(n) _____ with an alcohol cannot be used to prepare an ester.

What is the major organic product obtained from the following reaction?

What is "X" in the following reaction? ​

Which of the following is the correct order of decreasing reactivity in hydrolysis reactions (more reactive > less reactive)?

What is the major organic product obtained from the following reaction?

Esters react with alcohols in an acid-catalyzed reaction called _____. ​

Which of the following is the correct order of decreasing leaving group ability in nucleophilic acyl substitutions (better leaving group > worse leaving group)?

Which of the following statements is not true in relation to the hydrolysis of esters?

What is the major organic product obtained from the following reaction?

_____ do not react with ammonia, primary amines, and secondary amines.

Which of the following is the correct order of decreasing acid strength of the following compounds (more acidic > less acidic)?

What is the IUPAC name of the following compound?

What is the major organic product obtained from the following reaction?

What two organic compounds are obtained from the following reaction?

What is the major organic product obtained from the following reaction?

Consider the isotopically tagged substance below. Saponification of this substance will produce the following products. +CH3CH2CH2OH+ \quad\mathrm{CH}_{3} \mathrm{CH}_{2} \mathrm{CH}_{2} \mathrm{OH}+CH3​CH2​CH2​OH

Consider the following 1H NMR spectrum. The line indicated with the number _____ would indicate the presence of a C=O group.

What is the major organic product obtained from the following reaction?

What is the major organic product obtained from the following reaction?

Covalent Bonding and Shapes of Molecules

Alkanes and Cycloalkanes

Stereoisomerism and Chirality

Acids and Bases

Alkenes: Bonding, Nomenclature, and Properties

Reactions of Alkenes

Alkynes

Haloalkanes, Halogenation, and Radical Reactions

Nucleophilic Substitution and Beta-Elimination

Alcohols

Ethers, Epoxides, and Sulfides

Infrared Spectroscopy

Nuclear Magnetic Resonance Spectroscopy

Mass Spectrometry

An Introduction to Organometallic Compounds

Aldehydes and Ketones

Carboxylic Acids

Enolate Anions and Enamines

Dienes, Conjugated Systems, and Pericyclic Reactions

Benzene and the Concept of Aromaticity

Reactions of Benzene and Its Derivatives

Amines

Catalytic Carbon-Carbon Bond Formation

Carbohydrates

Lipids

Amino Acids and Proteins

Nucleic Acids

Organic Polymer Chemistry

Filters

What is "X" in the following reaction?

Esters react with alcohols in an acid-catalyzed reaction called _____.

Consider the following ¹H NMR spectrum. The line indicated with the number _____ would indicate the presence of a C=O group.