Exam 9: Nucleophilic Substitution and Beta-Elimination

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Which of the following represents the transition state of the rate-determining step in the reaction between 2-chloropropane and sodium amide leading to elimination? Which of the following represents the transition state of the rate-determining step in the reaction between 2-chloropropane and sodium amide leading to elimination?

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C

What is the best choice of reagent to perform the following transformation? What is the best choice of reagent to perform the following transformation?

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A

What is the major organic product obtained from the following reaction? What is the major organic product obtained from the following reaction?

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Which of the following statements related to SN1 reactions is not true?

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Which of the following is most likely to undergo rearrangement during reaction with methanol? Which of the following is most likely to undergo rearrangement during reaction with methanol?

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Which of the following statements is not true regarding SN2 reactions?

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Which of the following compounds undergoes the most rapid hydrolysis reaction? Which of the following compounds undergoes the most rapid hydrolysis reaction?

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The rate law for the following reaction would be of the form Rate = k[A][B]. The rate law for the following reaction would be of the form Rate = k[A][B].

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What is the major organic product obtained from the following reaction? What is the major organic product obtained from the following reaction?

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What is the equation for the rate of formation of 2-methoxypropane, CH3CH(OCH3)CH3, from the reaction of 2-bromopropane (i-PrBr) with methanol?

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What is the equation for the rate of formation of 1-iodobutane from the reaction of 1-chlorobutane (BuCl) with NaI by an SN2 mechanism?

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What is the major organic product obtained from the following reaction? What is the major organic product obtained from the following reaction?

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What is the major product formed upon treatment of (R) 2-bromohexane with sodium cyanide?

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What is the major organic product(s) obtained from the following reaction? What is the major organic product(s) obtained from the following reaction?

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What is the equation for the rate of formation of 2-methoxypropane, (CH3CH(OCH3)CH3, from the reaction of 2-bromopropane (i-PrBr) with sodium methoxide (NaOCH3)?

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Draw all of the chloroalkanes that undergo base-promoted dehydrochlorination to form the following alkene? Draw all of the chloroalkanes that undergo base-promoted dehydrochlorination to form the following alkene?

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Which of the following represents the transition state of the reaction between methyl iodide and ammonia? Which of the following represents the transition state of the reaction between methyl iodide and ammonia?

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Draw all of the chloroalkanes that undergo base-promoted dehydrochlorination to form the following alkene? Draw all of the chloroalkanes that undergo base-promoted dehydrochlorination to form the following alkene?

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Which of the following anions is the most nucleophilic in polar protic solvents?

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What is the major organic product obtained from the following reaction? What is the major organic product obtained from the following reaction?

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