Question 1

Which of the following describes the function of the large delta antigen,produced by hepatitis delta virus?

Accepted Answer

A) It stimulates the binding of the host cell RNA polymerase for genome replication. 
B) It carries out the cleavage of the genome multimers into monomers. 
C) It is required to package the genome into the hepatitis B virions. 
D) It forms capsids to package the hepatitis delta virus genome. 
E) It ligates the ends of the RNA genomes together. 
A) It stimulates the binding of the host cell RNA polymerase for genome replication. 
B) It carries out the cleavage of the genome multimers into monomers. 
C) It is required to package the genome into the hepatitis B virions. 
D) It forms capsids to package the hepatitis delta virus genome. 
E) It ligates the ends of the RNA genomes together.

Question 2

The formation of the antigenome template of hepatitis delta virus requires which of the following cellular enzymes?

Accepted Answer

A) DNA polymerase 
B) RNA-dependent RNA polymerase 
C) RNA polymerase I 
D) RNA polymerase II 
E) RNA polymerase III 
A) DNA polymerase 
B) RNA-dependent RNA polymerase 
C) RNA polymerase I 
D) RNA polymerase II 
E) RNA polymerase III

Question 3

There is some controversy about whether the replication of the hepatitis delta virus (HDV)genome is performed by the cellular RNA polymerase I or RNA polymerase II.Describe the evidence that supports each model.

Accepted Answer

There are two observations that support

Question 4

Which of the following mechanisms is used to produce the two different forms of the delta antigen from the hepatitis delta virus?

Accepted Answer

A) RNA editing by the insertion of an extra base into the mRNA. 
B) RNA editing by deamination of a specific base in the genome. 
C) Alternative mRNA splicing. 
D) Translational readthrough of a stop codon. 
E) Ribosomal frameshifting. 
A) RNA editing by the insertion of an extra base into the mRNA. 
B) RNA editing by deamination of a specific base in the genome. 
C) Alternative mRNA splicing. 
D) Translational readthrough of a stop codon. 
E) Ribosomal frameshifting.

Question 5

The RNA polymerase that copies the genome of the avocado sunblotch viroid is highly sensitive to the toxin $\alpha$-amanitin.

Accepted Answer

A) True 
 B)False

Exam 31: Viroids and Hepatitis Delta Virus

Which of the following describes the function of the large delta antigen,produced by hepatitis delta virus?

The formation of the antigenome template of hepatitis delta virus requires which of the following cellular enzymes?

There is some controversy about whether the replication of the hepatitis delta virus (HDV)genome is performed by the cellular RNA polymerase I or RNA polymerase II.Describe the evidence that supports each model.

Which of the following mechanisms is used to produce the two different forms of the delta antigen from the hepatitis delta virus?

The RNA polymerase that copies the genome of the avocado sunblotch viroid is highly sensitive to the toxin α\alphaα -amanitin.

Introduction to Virology 2

Virus Structure and Assembly

Virus Classification: the World of Viruses

Virus Entry

Single-Stranded Rna Bacteriophages

Microviruses

Bacteriophage

Bacteriophage Lambda

Viruses of Archaea

Cucumber Mosaic Virus

Picornaviruses

Flaviviruses

Togaviruses

Coronaviruses

Paramyxoviruses and Rhabdoviruses

Filovirouses

Bunyaviruses

Influenza Viruses

Reoviruses

Parvoviruses

Polyomaviruses

Papillomaviruses

Adenoviruses

Herpesviruses

Baculoviruses

Poxviruses

Viruses of Algae and Mimivirus

Retroviruses

Human Immunodeficiency Virus

Hepadnaviruses

Prions

Intrinsic Cellular Defenses Against Virus Infection

Innate and Adaptive Immune Responses to Virus Infection

Antiviral Vaccines

Antiviral Chemotherapy

Eukaryotic Virus Vectors

Filters

The RNA polymerase that copies the genome of the avocado sunblotch viroid is highly sensitive to the toxin $\alpha$ -amanitin.