Question 1

During an infection with Listeria,an intracellular bacterium,APCs will present antigen on MHC II molecules.

Accepted Answer

A) True 
 B)False

Question 2

The perforin-granzyme pathway involves

Accepted Answer

A)  the production of fever, which kills the pathogen. 
B)  the production of antibodies toward the invading pathogen. 
C)  the synthesis of special cell-killing proteins that act on infected or abnormal cells. 
D)  presenting the foreign antigen to B cells. 
E)  binding CD95L to infected cells, which eventually leads to cell apoptosis. 
A)  the production of fever, which kills the pathogen. 
B)  the production of antibodies toward the invading pathogen. 
C)  the synthesis of special cell-killing proteins that act on infected or abnormal cells. 
D)  presenting the foreign antigen to B cells. 
E)  binding CD95L to infected cells, which eventually leads to cell apoptosis.

Question 3

Which of the following statements concerning B cell receptors (BCRs)is FALSE?

Accepted Answer

A)  They are formed in response to an encounter with an antigen. 
B)  They are complementary in shape to a specific antigenic determinant that they may or may not encounter. 
C)  They are bound to the surface of B lymphocytes and have two antigen-binding sites. 
D)  Each B lymphocyte is randomly generated with antibody variable regions that determine its BCR. 
E)  Scientists estimate that each person forms at least 1011 different types of B lymphocytes with distinct BCRs. 
A)  They are formed in response to an encounter with an antigen. 
B)  They are complementary in shape to a specific antigenic determinant that they may or may not encounter. 
C)  They are bound to the surface of B lymphocytes and have two antigen-binding sites. 
D)  Each B lymphocyte is randomly generated with antibody variable regions that determine its BCR. 
E)  Scientists estimate that each person forms at least 1011 different types of B lymphocytes with distinct BCRs.

Question 4

Compare and contrast clonal deletion and clonal selection of B lymphocytes.

Accepted Answer

Both clonal deletion and clonal selectio

Question 5

What is the role of interleukins?

Accepted Answer

A)  chemotaxis of leukocytes 
B)  production of virally infected cells 
C)  ensuring production of enough leukocytes 
D)  signaling between leukocytes 
E)  complement activation 
A)  chemotaxis of leukocytes 
B)  production of virally infected cells 
C)  ensuring production of enough leukocytes 
D)  signaling between leukocytes 
E)  complement activation

Question 6

The (constant/end/variable)regions from the light and heavy chains of an antibody combine to form antigen-binding sites.

Accepted Answer

The answer of The (constant/end/variable)regions from the light and heavy...

Question 7

The immunological synapse refers to the

Accepted Answer

A)  interaction between a T cell and an antigen-presenting cell to produce a specialized contact area for communication between these cells. 
B)  activation of a B cell to become a plasma cell. 
C)  interaction between lymphocytes and foreign antigens to produce memory cells. 
D)  binding of a monocyte or macrophage to antigen so that it can act as an antigen-presenting cell. 
E)  interaction of the many cytokines produced by different immunological cells. 
A)  interaction between a T cell and an antigen-presenting cell to produce a specialized contact area for communication between these cells. 
B)  activation of a B cell to become a plasma cell. 
C)  interaction between lymphocytes and foreign antigens to produce memory cells. 
D)  binding of a monocyte or macrophage to antigen so that it can act as an antigen-presenting cell. 
E)  interaction of the many cytokines produced by different immunological cells.

Question 8

Which of the following best describes IgM antibodies?

Accepted Answer

A)  They cause basophils and eosinophils to degranulate. 
B)  They are the most common type of antibody in the blood during the initial phases of an immune response. 
C)  They are the antibody class found in body secretions. 
D)  They interact with phagocytes and NK cells. 
E)  They can cross the placenta to provide passive immunity. 
A)  They cause basophils and eosinophils to degranulate. 
B)  They are the most common type of antibody in the blood during the initial phases of an immune response. 
C)  They are the antibody class found in body secretions. 
D)  They interact with phagocytes and NK cells. 
E)  They can cross the placenta to provide passive immunity.

Question 9

The majority of mature,self-tolerant lymphocytes are found in

Accepted Answer

A)  the MALT. 
B)  lymph nodes. 
C)  the thymus. 
D)  the spleen. 
E)  the tonsils. 
A)  the MALT. 
B)  lymph nodes. 
C)  the thymus. 
D)  the spleen. 
E)  the tonsils.

Question 10

Describe the mechanisms of action of antibodies.

Accepted Answer

Antibodies act against foreign antigens

Question 11

When a T cell's CD95L binds to the CD95 on a target cell,antibodies are formed.

Accepted Answer

A) True 
 B)False

Question 12

Large molecules such as polymers make good antigens.

Accepted Answer

A) True 
 B)False

Question 13

Class I MHC molecules are essential for

Accepted Answer

A)  presentation of endogenous antigens. 
B)  recognition of chemokines. 
C)  detection of IL-2. 
D)  recognition of class II MHC. 
E)  presentation of exogenous antigens. 
A)  presentation of endogenous antigens. 
B)  recognition of chemokines. 
C)  detection of IL-2. 
D)  recognition of class II MHC. 
E)  presentation of exogenous antigens.

Question 14

The antibody-binding site of an antibody is made up of

Accepted Answer

A)  portions of both of the heavy chains only. 
B)  the variable regions of the heavy chains. 
C)  the light chains only. 
D)  the variable regions of both light and heavy chains. 
E)  one heavy chain. 
A)  portions of both of the heavy chains only. 
B)  the variable regions of the heavy chains. 
C)  the light chains only. 
D)  the variable regions of both light and heavy chains. 
E)  one heavy chain.

Question 15

B cells are activated when they interact with (antigen-presenting/Th1/Th2)cells.

Accepted Answer

The answer of B cells are activated when they interact...

Question 16

Which of the following is NOT included in the MALT?

Accepted Answer

A)  the appendix 
B)  the spleen 
C)  Peyer's patches 
D)  lymphoid tissue in the respiratory tract 
E)  lymphoid tissue in the small intestine 
A)  the appendix 
B)  the spleen 
C)  Peyer's patches 
D)  lymphoid tissue in the respiratory tract 
E)  lymphoid tissue in the small intestine

Question 17

A single B lymphocyte can recognize multiple antigenic determinants.

Accepted Answer

A) True 
 B)False

Question 18

Exogenous antigens are processed for immune recognition by ________ cells.

Accepted Answer

A)  dendritic 
B)  all nucleated 
C)  macrophage 
D)  helper T 
E)  dendritic and macrophage 
A)  dendritic 
B)  all nucleated 
C)  macrophage 
D)  helper T 
E)  dendritic and macrophage

Question 19

You step on something in the yard resulting in a puncture wound that does not bleed freely.Antigens from any microbes that entered the wound will most likely end up in the

Accepted Answer

A)  appendix. 
B)  lymph nodes of the groin. 
C)  lymph nodes of the neck (cervical). 
D)  lymph nodes of the armpit (axilla). 
E)  spleen. 
A)  appendix. 
B)  lymph nodes of the groin. 
C)  lymph nodes of the neck (cervical). 
D)  lymph nodes of the armpit (axilla). 
E)  spleen.

Question 20

Which of the following statements regarding antibody function is FALSE?

Accepted Answer

A)  They can prevent virus attachment to host cells. 
B)  They can facilitate phagocyte attack on bacteria with a capsule (glycocalyx). 
C)  They can penetrate host cells to bind intracellular antigens. 
D)  They can facilitate cytotoxic attack by natural killer lymphocytes. 
E)  They can bind more than one pathogen at a time, forming complexes. 
A)  They can prevent virus attachment to host cells. 
B)  They can facilitate phagocyte attack on bacteria with a capsule (glycocalyx). 
C)  They can penetrate host cells to bind intracellular antigens. 
D)  They can facilitate cytotoxic attack by natural killer lymphocytes. 
E)  They can bind more than one pathogen at a time, forming complexes.

Exam 16: Adaptive Immunity

During an infection with Listeria,an intracellular bacterium,APCs will present antigen on MHC II molecules.

The perforin-granzyme pathway involves

Which of the following statements concerning B cell receptors (BCRs)is FALSE?

Compare and contrast clonal deletion and clonal selection of B lymphocytes.

What is the role of interleukins?

The (constant/end/variable)regions from the light and heavy chains of an antibody combine to form antigen-binding sites.

The immunological synapse refers to the

Which of the following best describes IgM antibodies?

The majority of mature,self-tolerant lymphocytes are found in

Describe the mechanisms of action of antibodies.

When a T cell's CD95L binds to the CD95 on a target cell,antibodies are formed.

Large molecules such as polymers make good antigens.

Class I MHC molecules are essential for

The antibody-binding site of an antibody is made up of

B cells are activated when they interact with (antigen-presenting/Th1/Th2)cells.

Which of the following is NOT included in the MALT?

A single B lymphocyte can recognize multiple antigenic determinants.

Exogenous antigens are processed for immune recognition by ________ cells.

You step on something in the yard resulting in a puncture wound that does not bleed freely.Antigens from any microbes that entered the wound will most likely end up in the

Which of the following statements regarding antibody function is FALSE?

A Brief History of Microbiology

The Chemistry of Microbiology

Cell Structure and Function

Microscopy, Staining, and Classification

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Infection, Infectious Diseases, and Epidemiology

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