Exam 15: Drug Metabolomics and Proteomics Analysis in Drug Delivery and Discovery

Phosphorylation is a metabolic & signaling processes particularly take place in which amino acid residues____________,____________,and __________ .

What type of detectors used in mass spectrometry?

Peptides are linear short polymers of amino acids with less than fifty residues?

Carboxylation reaction takes place in a posttranslational modification of glutamate residues to anionic γ-carboxyglutamate which can bind cationic molecules

Match the routes of drug administration with their respective areas of action. Joints

Glycosylation is used to study multiple functions in the cell for molecular targeting and cell-cell recognition particularly with ________,__________,and ___________.

What is proteomics?

Protonated molecular ions [M+H]⁺ are formed in

What are the most common available isotopic molecular weights for oxygen (O)?

Ions are extracted into the analyser region of the mass spectrometer according to their mass (m)-to-charge (z) ratios (m/z)

What are the most common available isotopic molecular weights for hydrogen (H)?

Phosphorylation is a chemical process in which a phosphate group is added to an organic molecules.

What is the use of stable isotope labeling by amino acid in cell culture (SILAC)?

Metabonomics is defined as

What is the description of bottom-up proteomics?

What are the most common available isotopic molecular weights for sulfur (S)?

What type of chemical groups are introduced by acetylation reaction in the cell?

Where proteomics approaches are used?

Transamidation reaction is primarily occurs in----

What are the most common available isotopic molecular weights for carbon (C)?