Exam 15: Drug Metabolomics and Proteomics Analysis in Drug Delivery and Discovery

Hydroxylation reaction is used to increase H-bonding & glycosylation sites which is primarily occurs on Pro,Lys.

What is the full form for LC-MS/MS?

Samples (M),multiply charged molecular-related ions such as ___ in positive ionisation mode and ___ in negative ionisation mode.

Match the ABC transporter with the respective number of TMDs. BCRP

What is the name of reaction which takes place in primary amide groups and secondary and tertiary amine groups?

What type of tandem mass spectrometry ionization techniques have been used for proteomics analysis?

What types of mass analyzers used in protein and peptide analysis?

What is residue of protein?

What different non-radioactive isotopic labeling techniques are used in protein purification and isolation for proteomic?

In positive ionization mode tandem (MS-MS),a trace of ___ is usually added to induce ___ of the sample molecules

Match the routes of drug administration with their respective areas of action. Brain

Where electrospray Ionization (ESI) is occurs in the tandem mass spectrometry?

Acetylation chemical process used for charge weaken interactions with DNA and which is primarily takes place in unique amino acid residue. What is that?

MALDI method predominantly generate a singly charged molecular-related ions regardless of the molecular mass.

What are the most common available isotopic molecular weights for nitrogen (N)?