Exam 14: Evolution and Human Health
Analysis of the phylogeny of flu viruses reveals that the two 1968 strains (see the accompanying figures)both carry neuraminidase N2,but their hemagglutinins are distantly related (H2 and H3).Moreover,before the global pandemic of 1968,human flu viruses had never carried H3.This observation suggests that ________.



D
The idea that fundamental aspects of human behavior are "hardwired" or "programmed" by human genes is sometimes called ________.[two words]
genetic determinism
The 2011 medical thriller film Contagion revolves around a fictional virus called MEV-1,which causes flu-like symptoms followed by seizures and encephalitis; about 25% of infected patients die.MEV-1 appeared as a result of accidental genetic exchange between a bat virus and a pig virus.Discuss the plausibility of this scenario in the light of recent work on viruses and their evolution.
The scenario presented in the film Contagion, where a fictional virus called MEV-1 is created through accidental genetic exchange between a bat virus and a pig virus, is not entirely implausible in the context of recent work on viruses and their evolution.
In reality, viruses are known to undergo genetic mutations and recombination events, which can lead to the emergence of new strains or even entirely new viruses. This process is particularly common in RNA viruses, such as influenza and coronaviruses, due to their high mutation rates and ability to exchange genetic material with other viruses.
Furthermore, zoonotic transmission, where a virus jumps from animals to humans, is a well-documented phenomenon. Many infectious diseases, including Ebola, HIV, and SARS, are believed to have originated in animals before spilling over into human populations.
While the specific details of MEV-1's creation in the film may be exaggerated for dramatic effect, the general concept of a novel virus emerging through genetic exchange between different animal viruses is not outside the realm of possibility. However, it's important to note that the likelihood of such an event occurring and causing a widespread outbreak like in the film is still relatively low, and the film's portrayal should not be taken as a prediction of real-world events.
The immune system recognizes and reacts to ________,[two words] specific parts of a foreign protein.
Analysis of the 1918 and 2009 flu epidemics reveals that the most likely scenario was that ________.
Despite some evidence that antibiotic resistance can confer a fitness disadvantage to bacteria in nonantibiotic environments as compared to susceptible strains,research has also documented that ________.
Your text discusses one of the most well-known examples in which human populations have evolved in response to selection imposed by changes in lifestyle.Specifically,this example has to do with a change toward the life-long production of an enzyme that allows humans to digest something our ancestors normally would have ingested only as infants.What is the name of this enzyme?
The ________ [two words] hypothesis for the evolution of virulence states that pathogens may evolve traits that enhance their chances of survival within a host,but that decrease their chances of being spread to a new host.
Evidence for the evolution of antibiotic resistance in bacteria has been evaluated ________.
The frequency of antibiotic-resistant bacteria tends to go down when the bacterial population is no longer being exposed to the antibiotic.This implies that bacterial antibiotic resistance mechanisms have a significant ________ to the bacterial population.
Research on conditions that are relatively new to human populations such as myopia,breast cancer,and obesity support the conclusion that ________.
Determining the effects of natural selection on human behavior is much more robust if ________.
Given that humans shifted from hunter-gathers to an agriculturally based society within the last 10,000 years does NOT mean that ________.
Two evolutionary hypotheses on the function of fever have been suggested: A fever may reflect manipulation of the host by the pathogen,to the pathogen's benefit,or a fever may be an adaptive response by the host to help to control the pathogen itself.Studies on whether the use of fever-reducing drugs were helpful or interfered with the body's ability to fight the pathogen ________.
The relation between the variation in a phenotypic trait and the variation in an environmental variable―in other words,the pattern of phenotypic plasticity in a trait―is called a ________.[two words]
The statement "Natural selection should favor pathogens that strike an optimal balance between the costs and benefits of harming their hosts" describes ________.
An insect or other organism that transmits disease from one host to another is called a ________.
The statement "The virulence of many pathogens in humans may not be a target of selection itself,but rather an accidental by-product of selection on other traits" describes ________.
In the late 1980s and early 1990s,the percentage of Icelandic children whose bacterial infections were caused by bacteria resistant to penicillin rose at an alarming rate.After public health officials initiated a campaign to reduce the use of penicillin,resistance dropped off.(See the accompanying figure.)
This observation is consistent with the hypothesis that ________.

The specific parts of foreign proteins that the immune system recognizes and "remembers" are called ________.
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