Exam 12: Exercise and the Prevention of Chronic Diseases: the Role of Cytokines and the Anti-Inflammatory Effects of Exercise

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Which cytokine produced by Treg cells has several inhibitory effects on immune cell functions?

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E

Monocyte TLR4 expression is generally lower in young unfit individuals compared with older fit individuals.

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False

Catecholamines upregulate the lipopolysaccharide-induced production of TNF-α, IL-6 and IL-1β by immune cells.

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Which of the following tissues is responsible for the chronic low-grade inflammation that is associated with increased chronic disease risk in later life?

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The main trigger for increased infiltration of macrophages into adipose tissue is thought to be...

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Increased insulin resistance in type 2 diabetes is not caused by any known immune mechanisms.

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Exercise suppresses the secretion of Th2 cytokines more than Th1 cytokines.

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The inflammatory (CD14+CD16+) monocytes normally constitute about what percentage of the total blood monocyte population?

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M1 macrophages produce TNF-a and IL-6 while the M2 macrophages produce anti-inflammatory cytokines and arginase.

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The major source of IL-6 in the circulation during exercise comes from...

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