Exam 15: The Chromosomal Basis of Inheritance

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What is the chromosomal system of sex determination in most species of ants and bees?

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Correns described that the inheritance of variegated color on the leaves of certain plants was determined by the maternal parent only. What phenomenon does this describe?

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A man with hemophilia (a recessive, sex-linked condition)has a daughter of normal phenotype. She marries a man who is normal for the trait. What is the probability that a daughter of this mating will be a hemophiliac? That a son will be a hemophiliac? If the couple has four sons, what is the probability that all four will be born with hemophilia?

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0; 1⁄2, 1/16

In humans, male-pattern baldness is controlled by an autosomal gene that occurs in two allelic forms. Allele Hn determines nonbaldness, and allele Hb determines pattern baldness. In males, because of the presence of testosterone, allele Hb is dominant over Hn. If a man and woman both with genotype HnHb have a son, what is the chance that he will eventually be bald?

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Morgan and his colleagues worked out a set of symbols to represent fly genotypes. Which of the following are representative?

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Cinnabar eyes is a sex-linked recessive characteristic in fruit flies. If a female having cinnabar eyes is crossed with a wild-type male, what percentage of the F1 males will have cinnabar eyes?

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SRY is best described in which of the following ways?

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Map units on a linkage map cannot be relied upon to calculate physical distances on a chromosome for which of the following reasons?

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You design Drosophila crosses to provide recombination data for gene a, which is located on the chromosome shown in Figure 15.12 in the textbook. Gene a has recombination frequencies of 14% with the vestigial-wing locus and 26% with the brown-eye locus. Where is a located on the chromosome?

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What is the mechanism for the production of genetic recombinants?

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The frequency of Down syndrome in the human population is most closely correlated with which of the following?

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Bananas plants, which are triploid, are seedless and therefore sterile. Propose a possible explanation.

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Why did the improvement of microscopy techniques in the late 1800s set the stage for the emergence of modern genetics?

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What pattern of inheritance would lead a geneticist to suspect that an inherited disorder of cell metabolism is due to a defective mitochondrial gene?

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The frequency of crossing over between any two linked genes will be which of the following?

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In another cross, a wild-type fruit fly (heterozygous for gray body color and red eyes)is mated with a black fruit fly with purple eyes. The offspring are as follows: wild type, 721; black-purple, 751; gray-purple, 49; black-red, 45. What is the recombination frequency between these genes for body color and eye color? Using information from problem 4, what fruit flies (genotypes and phenotypes)would you mate to determine the sequence of the body-color, wing-size, and eye-color genes on the chromosome?

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What is the chromosomal system for determining sex in mammals?

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In cats, black fur color is caused by an X-linked allele; the other allele at this locus causes orange color. The heterozygote is tortoiseshell. What kinds of offspring would you expect from the cross of a black female and an orange male?

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What is the source of the extra chromosome 21 in an individual with Down syndrome?

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Which of the following statements describes genomic imprinting?

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