Exam 12: Genes and Cancer

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Many specialized cells,such as white blood cells,____.

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A

Epigenetics is the study of heritable alterations in gene expression caused by ____.

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Formation of ____________________ is an intermediate stage in the development of colon cancer.

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polyps

A characteristic of all cancers is that ____.

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Cancer-causing mutations of the cell cycle ____.

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Abnormal epigenetic patterns of DNA ____________________ are associated with many types of cancer,and the removal of ____________________ groups can activate genes involved with cell growth and can increase genomic instability.

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One of the steps in converting normal cells into cancerous cells may be the ____________________ and silencing of both copies of the NOEY2 gene.

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All the cells in a cancerous tumor are ____________________ directly descended from one cell.

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The five-year survival rate of ____________________ cancer is only 13%.

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Radiation and chemotherapy are the best treatments for cancer because they are very specific and destroy only cancerous cells.

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The mutant BRCA1 gene imparts a dominantly inherited predisposition to breast cancer.

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A(n)____________________ between chromosome 9 and chromosome 22 in chronic myelogenous leukemia results in a Philadelphia chromosome.

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An autosomal dominant trait called familial adenomatous polyposis (FAP)results in the development of polyps and benign growths in the colon and is coupled with ____________________ instability.

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A cellular molecular pathway by which an external signal is converted into a functional response is called ____________________.

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About ____ of all cancer cases have a hereditary component.

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There are no direct-to-consumer genetic tests available that screen for breast cancer susceptibility.

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One of the properties of cancer is its ability to spread,or ____________________,to other sites in the body.

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Cancer causing mutations are always the result of chromosomal rearrangements.

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Drug therapies that target only cancer cells rather than all dividing cells in the body stop the growth of cancer by blocking the action of ____________________ proteins on the growth and division on malignant cells.

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During metabolism,cancer-causing ____ are generated.

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