Exam 17: Genes and The Immune System

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B and T cells become activated and divide to produce identical cells when _____.

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The best animal models for xenotransplantation of organs into humans are the nonhuman primates,such as chimpanzees and baboons.

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In an inflammatory response,the direct effect of histamine is to ____.

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Suppose an Rh- mother gives birth to an Rh- baby. Is there a danger of hemolytic disease of the newborn developing during a subsequent pregnancy? Why or why not?

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____________________ T cells secrete interleukins that activate other cells in both the cell-mediated and antibody-mediated immune responses.

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The huge diversity of antibody molecules is generated by the shuffling of gene segments in T cells.

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The technology of transplanting nonhuman organs into humans is known as _____.

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Suppose that an infectious agent,such as a virus or bacterium,had surface antigens identical to those displayed on the surface of human cells.Would the immune system be able to detect and destroy these agents? Why or why not?

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The process by which an antigen binds to a specific antibody on a naïve B cell,thereby triggering mitosis and the build-up of a large population of antibody-secreting plasma cells (also known as effector B cells),is called ____________________.

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When the immune systems no longer distinguishes between self and nonself,_____ can result.

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Which immune system(s)are absent in individuals with severe combined immunodeficiency?

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Do you agree with the strategy of xenotransplantation to alleviate the shortage of donated human organs?  Why or why not?

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The membrane-attack complex is a group of proteins that supplements the inflammatory response.

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What is the underlying molecular cause of Crohn's disease?

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What is most closely associated with membrane-attack complexes (MACs)?

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What occurs during the antigen detection stage of the antibody-mediated immune response initiated by T cell activation?

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The _____ of an antibody molecule functions to recognize and bind to a specific antigen.

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The major obstacle to the use of xenotransplants can possibly be overcome by ____.

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John and all his brothers have no antibodies caused by non-functional B cells.Therefore,they are highly susceptible to bacterial infections.John and his brothers most likely have a condition called ____________________.

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When species-specific MHC proteins on xenotransplants trigger a complement-mediated rejection in the recipient,a(n)____________________ results.

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