Question 1

Immunotherapy is the

Accepted Answer

A) use of antitoxins. 
B) use of immune serum globulin. 
C) conferring of passive immunity. 
D) administering of preformed antibodies. 
E) All of the choices are correct. 
A) use of antitoxins. 
B) use of immune serum globulin. 
C) conferring of passive immunity. 
D) administering of preformed antibodies. 
E) All of the choices are correct.

Question 2

Gamma globulin can be given as immunotherapy to confer artificial passive immunity.

Accepted Answer

A) True 
 B)False

Question 3

Class II MHC genes code for

Accepted Answer

A) certain secreted complement components. 
B) self receptors recognized by T lymphocytes. 
C) all HLA antigens. 
D) receptors located primarily on macrophages and B cells. 
E) All of the choices are correct. 
A) certain secreted complement components. 
B) self receptors recognized by T lymphocytes. 
C) all HLA antigens. 
D) receptors located primarily on macrophages and B cells. 
E) All of the choices are correct.

Question 4

Acellular vaccines and subunit vaccines

Accepted Answer

A) contain modified bacterial exotoxin molecules. 
B) are always genetically engineered. 
C) contain select antigenic components of a pathogen rather than whole cells or viruses. 
D) confer passive immunity. 
E) utilize DNA strands that will produce the antigen. 
A) contain modified bacterial exotoxin molecules. 
B) are always genetically engineered. 
C) contain select antigenic components of a pathogen rather than whole cells or viruses. 
D) confer passive immunity. 
E) utilize DNA strands that will produce the antigen.

Question 5

Which of the following is not a target for TC cells?

Accepted Answer

A) bacteria 
B) virus-infected cells 
C) cancer cells 
D) human transplanted liver 
E) pig transplanted heart 
A) bacteria 
B) virus-infected cells 
C) cancer cells 
D) human transplanted liver 
E) pig transplanted heart

Question 6

The immunoglobulin class that has a dimer form found in mucus,saliva,colostrum,and other body secretions is

Accepted Answer

A) IgA. 
B) IgD. 
C) IgE. 
D) IgG. 
E) IgM. 
A) IgA. 
B) IgD. 
C) IgE. 
D) IgG. 
E) IgM.

Question 7

Plasma cells

Accepted Answer

A) secrete antibodies. 
B) function in allergic reactions. 
C) directly destroy target cells. 
D) suppress immune reactions. 
E) activate B cells and other T cells. 
A) secrete antibodies. 
B) function in allergic reactions. 
C) directly destroy target cells. 
D) suppress immune reactions. 
E) activate B cells and other T cells.

Question 8

All nucleated cells contain___.

Accepted Answer

A) class I MHC 
B) class II MHC 
C) secretory antibodies 
D) IgE receptors 
E) IgM molecules 
A) class I MHC 
B) class II MHC 
C) secretory antibodies 
D) IgE receptors 
E) IgM molecules

Question 9

Class I MHC genes code for

Accepted Answer

A) certain secreted complement components. 
B) self receptors recognized by T lymphocytes. 
C) all HLA antigens. 
D) receptors located primarily on macrophages and B cells. 
E) All of the choices are correct. 
A) certain secreted complement components. 
B) self receptors recognized by T lymphocytes. 
C) all HLA antigens. 
D) receptors located primarily on macrophages and B cells. 
E) All of the choices are correct.

Question 10

Cell surface markers involved in immune reactions

Accepted Answer

A) are the result of genetic expression. 
B) function in recognition of self molecules. 
C) receive and transmit chemical messages among other cells of the system. 
D) aid in cellular development. 
E) All of the choices are correct. 
A) are the result of genetic expression. 
B) function in recognition of self molecules. 
C) receive and transmit chemical messages among other cells of the system. 
D) aid in cellular development. 
E) All of the choices are correct.

Question 11

Superantigens are

Accepted Answer

A) body tissues that the immune system mistakes as foreign. 
B) cell markers found in some member of a species but not in other members. 
C) bacterial toxins that activate T cells at a 100 times greater rate than other antigens. 
D) those that evoke allergic reactions. 
E) None of the choices is correct. 
A) body tissues that the immune system mistakes as foreign. 
B) cell markers found in some member of a species but not in other members. 
C) bacterial toxins that activate T cells at a 100 times greater rate than other antigens. 
D) those that evoke allergic reactions. 
E) None of the choices is correct.

Question 12

Which of the following is a special binding substance that enhances immunogenicity and prolongs antigen retention at the injection site?

Accepted Answer

A) adjuvant 
B) booster 
C) antibodies to toxin 
D) gamma globulin 
E) "trojan horse" recombinant vaccine 
A) adjuvant 
B) booster 
C) antibodies to toxin 
D) gamma globulin 
E) "trojan horse" recombinant vaccine

Question 13

Antigen-presenting cells

Accepted Answer

A) include dendritic cells. 
B) include macrophages. 
C) engulf and modify antigen to be more immunogenic. 
D) hold and present processed antigen on their cell membrane surface. 
E) All of the choices are correct. 
A) include dendritic cells. 
B) include macrophages. 
C) engulf and modify antigen to be more immunogenic. 
D) hold and present processed antigen on their cell membrane surface. 
E) All of the choices are correct.

Question 14

Which is incorrect about the Fc region of an immunoglobulin?

Accepted Answer

A) is called the crystallizable fragment 
B) forms the antigen binding sites 
C) contains an effector molecule that can bind to cells such as macrophages and mast cells 
D) contains an effector molecule that can fix complement 
E) determines the class to which the immunoglobulin belongs 
A) is called the crystallizable fragment 
B) forms the antigen binding sites 
C) contains an effector molecule that can bind to cells such as macrophages and mast cells 
D) contains an effector molecule that can fix complement 
E) determines the class to which the immunoglobulin belongs

Question 15

Properties of effective antigens include all the following except

Accepted Answer

A) are foreign to the immune system. 
B) have molecular complexity. 
C) are large molecules with a minimum molecular weight of 1,000. 
D) have large polymers made up of repeating subunits. 
E) are cells or large,complex molecules. 
A) are foreign to the immune system. 
B) have molecular complexity. 
C) are large molecules with a minimum molecular weight of 1,000. 
D) have large polymers made up of repeating subunits. 
E) are cells or large,complex molecules.

Question 16

The monomer subunit of immunoglobulin molecules has all the following except

Accepted Answer

A) two identical heavy polypeptide chains. 
B) two identical light polypeptide chains. 
C) disulfide bonds between polypeptide chains. 
D) four antigen binding sites. 
E) a variable and constant region on each polypeptide chain. 
A) two identical heavy polypeptide chains. 
B) two identical light polypeptide chains. 
C) disulfide bonds between polypeptide chains. 
D) four antigen binding sites. 
E) a variable and constant region on each polypeptide chain.

Question 17

Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format.
  The Smith family has brought their 2-week-old son into your family practice office for his 2-week checkup. He is their first son, and they are very anxious. They have already expressed multiple concerns to you concerning sleep, feeding, and crying, but their concerns have been about things that are typical for a newborn. You try your best to calm their fears, and they are receptive for the most part. However, when it comes time to discuss vaccination with them, they refuse to vaccinate their son because they report they have heard vaccines can cause autism in children. 
-The Smiths are concerned when they hear that vaccines consist of microbes,even if they have been inactivated.They say that they do not want whole bacteria being put into their son,even if it is inactive.What is a proper response?

Accepted Answer

A) "The bacteria is inactive,so there's no risk of it harming your son." 
B) "The chances of the bacteria infecting your son are very slim." 
C) "Vaccines haven't actually contained whole bacteria since 2008." 
D) "We keep our vaccines in the refrigerator here,and the cold inhibits mutations." 
A) "The bacteria is inactive,so there's no risk of it harming your son." 
B) "The chances of the bacteria infecting your son are very slim." 
C) "Vaccines haven't actually contained whole bacteria since 2008." 
D) "We keep our vaccines in the refrigerator here,and the cold inhibits mutations."

Question 18

Which process involves a more rapid synthesis and greatly increased titer of antibody when the immune system is subsequently exposed to the same antigen?

Accepted Answer

A) neutralization 
B) opsonization 
C) complement fixation 
D) agglutination 
E) memory response 
A) neutralization 
B) opsonization 
C) complement fixation 
D) agglutination 
E) memory response

Question 19

When an antibody is covering the foreign microorganism then complement may be activated via this___ pathway.

Accepted Answer

A) classical 
B) lectin 
C) alternative 
D) interleukin 
A) classical 
B) lectin 
C) alternative 
D) interleukin

Question 20

The histocompatibility complex proteins function in

Accepted Answer

A) recognition of self. 
B) antibody proliferation. 
C) B-cell maturation. 
D) T-cell maturation. 
E) None of the choices is correct. 
A) recognition of self. 
B) antibody proliferation. 
C) B-cell maturation. 
D) T-cell maturation. 
E) None of the choices is correct.

Exam 13: Host Defenses II: Specific Immunity and Immunization

Immunotherapy is the

Gamma globulin can be given as immunotherapy to confer artificial passive immunity.

Class II MHC genes code for

Acellular vaccines and subunit vaccines

Which of the following is not a target for TC cells?

The immunoglobulin class that has a dimer form found in mucus,saliva,colostrum,and other body secretions is

Plasma cells

All nucleated cells contain___.

Class I MHC genes code for

Cell surface markers involved in immune reactions

Superantigens are

Which of the following is a special binding substance that enhances immunogenicity and prolongs antigen retention at the injection site?

Antigen-presenting cells

Which is incorrect about the Fc region of an immunoglobulin?

Properties of effective antigens include all the following except

The monomer subunit of immunoglobulin molecules has all the following except

Which process involves a more rapid synthesis and greatly increased titer of antibody when the immune system is subsequently exposed to the same antigen?

When an antibody is covering the foreign microorganism then complement may be activated via this___ pathway.

The histocompatibility complex proteins function in

Introduction to Microbes and Their Building Blocks

Tools of the Laboratory: Methods for the Culturing and Microscopic Analysis

Bacteria and Archaea

Eukaryotic Cells and Microorganisms

Viral Structure and Life Cycles

Microbial Nutrition and Growth

Microbial Metabolism

Microbial Genetics and Genetic Engineering

Physical and Chemical Control of Microbes

Antimicrobial Treatment

Interactions Between Microbes and Humans

Host Defenses I: Overview and Nonspecific Defenses

Disorders in Immunity

Diagnosing Infections

Infectious Diseases Affecting the Skin and Eyes

Infectious Diseases Affecting the Nervous System

Infectious Diseases Affecting the Cardiovascular and Lymphatic Systems

Infectious Diseases Affecting the Respiratory Systems

Infectious Diseases Affecting the Gastrointestinal Tract

Infectious Diseases Affecting the Genitourinary System

One Health: The Interconnected Health of the Environment, humans, and Other Animals

Filters

Which of the following is not a target for T_C cells?