There Are Six Possible Reading Frames for Any Double-Stranded DNA

Short Answer

There are six possible reading frames for any double-stranded DNA. In the following schematic drawing of a genomic region in Escherichia coli, stop codons in each of these frames are indicated by black bars. In which reading frame do you think the open reading frame (ORF) is translated in this region? Write down the frame number as your answer, e.g. 2.