Which One of the Following Statements Regarding Positive and Negative

Multiple Choice

Which one of the following statements regarding positive and negative selection of T cells is NOT true?

A) Thymic epithelial cells present self-peptide-MHC to developing T cells undergoing the selection process.
B) T cells that do not recognize self-peptide-MHC die by neglect.
C) T cells that bind too strongly to self-peptide-MHC die by Fas ligand-mediated apoptosis.
D) During positive selection,developing T cells express higher levels of anti-apoptotic proteins such as bcl-2.
E) A breakdown in negative selection may result in the development of some autoimmune diseases.