Aspirin Has the Structure on the Left with a PK_a

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The Answer is a. The conjugate base of aspirin is formed by losing the acidic proton. The pK_a tells us that this is the carboxylic acid is the acidic group. The conjugate acid is the following anion:
$a. The conjugate base of aspirin is formed by losing the acidic proton. The pKa tells us that this is the carboxylic acid is the acidic group. The conjugate acid is the following anion: b. Calculate the fraction dissociated from the Henderson-Hasselbalch equation or, more easily, from Eq. 3.67a, with Δ = pH − pKa = 2 − 3.4 = −1.4. Therefore, aspirin is 3.8% ionized under these conditions. (If there is any doubt whether to use the equation with the Δ or −Δ in the denominator, we know that the fraction ionization is small because the pH is much lower than the pKa. Therefore, the second term in the denominator must be large.)$ b. Calculate the fraction dissociated from the Henderson-Hasselbalch equation or, more easily, from Eq. 3.67a, with Δ = pH − pK_a = 2 − 3.4 = −1.4.
$a. The conjugate base of aspirin is formed by losing the acidic proton. The pKa tells us that this is the carboxylic acid is the acidic group. The conjugate acid is the following anion: b. Calculate the fraction dissociated from the Henderson-Hasselbalch equation or, more easily, from Eq. 3.67a, with Δ = pH − pKa = 2 − 3.4 = −1.4. Therefore, aspirin is 3.8% ionized under these conditions. (If there is any doubt whether to use the equation with the Δ or −Δ in the denominator, we know that the fraction ionization is small because the pH is much lower than the pKa. Therefore, the second term in the denominator must be large.)$ Therefore, aspirin is 3.8% ionized under these conditions. (If there is any doubt whether to use the equation with the Δ or −Δ in the denominator, we know that the fraction ionization is small because the pH is much lower than the pK_a. Therefore, the second term in the denominator must be large.)

Aspirin Has the Structure on the Left with a PK_a

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Aspirin Has the Structure on the Left with a PKa

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Aspirin Has the Structure on the Left with a PK_a

Correct Answer:
Verified