Humans with Defective Expression of the Integrin LFA-1 Have an Immunodeficiency

Multiple Choice

Humans with defective expression of the integrin LFA-1 have an immunodeficiency disease characterized by the failure of lymphocytes and granulocytes to migrate to tissues at sites of infection or inflammation. A similar immunodeficiency would be expected if individuals had mutations disrupting the gene for:

A) CD3 $\zeta$
B) The complement receptor, CD21
C) WASp
D) Rap1
E) SLP-76