Small GTPases, Such as Ras, Rho, and Cdc42, Are Activated

Multiple Choice

Small GTPases, such as Ras, Rho, and cdc42, are activated when they exchange their bound GDP for GTP. In the GTP-bound state, these proteins contribute to signaling by:

A) Hydrolyzing the bound GTP back to GDP
B) Interacting with GTPase-activating proteins (GAPs)
C) Interacting with target proteins and altering their activity
D) Diffusing from the membrane and entering the nucleus
E) Inducing calcium release from the endoplasmic reticulum