Dideoxy Nucleotides That Are Used in DNA Sequencing Experiments Terminate

Multiple Choice

Dideoxy nucleotides that are used in DNA sequencing experiments terminate DNA synthesis because they:

A) cannot be recognized by DNA polymerases and therefore not incorporated during synthesis.
B) have methyl groups attached to the 5'position of the sugar and can't be incorporated during synthesis.
C) are only recognized by reverse transcriptases.
D) have no 3'-OH group and so no additional nucleotides can be added to them after they are incorporated.
E) have no phosphate groups.