Question 1

Primitive erythropoiesis in the yolk sac is important to what process?

Accepted Answer

A)  Transportation of oxygen to developing tissue 
B)  Development of immunity 
C)  Liver development 
D)  Cellular differentiation 
A)  Transportation of oxygen to developing tissue 
B)  Development of immunity 
C)  Liver development 
D)  Cellular differentiation

Question 2

Explain how the bone marrow receives nutrients to survive.

Accepted Answer

The bone marrow receives nutrients prima

Question 3

Where in the body does maturation of T lymphocytes take place?

Accepted Answer

A)  Lymph node 
B)  Bone marrow 
C)  Spleen 
D)  Thymus 
A)  Lymph node 
B)  Bone marrow 
C)  Spleen 
D)  Thymus

Question 4

A characteristic that defines a tissue as primary vs. secondary lymphoid tissue is:

Accepted Answer

A)  Activated cells reside in primary and resting cells reside in secondary lymphoid tissue 
B)  The quantity of cells in each 
C)  Primary tissue is composed of only T cells and secondary tissue is composed of only B cells 
D)  Immunocompetent T and B cells further divide into memory and effector cells in secondary tissue 
A)  Activated cells reside in primary and resting cells reside in secondary lymphoid tissue 
B)  The quantity of cells in each 
C)  Primary tissue is composed of only T cells and secondary tissue is composed of only B cells 
D)  Immunocompetent T and B cells further divide into memory and effector cells in secondary tissue

Question 5

Which of the following characterizes definitive erythropoiesis?

Accepted Answer

A)  A self-renewing HSC in the AGM 
B)  The production of erythroid cells in the liver 
C)  The presence of hemoglobin F in erythroid cells 
D)  Megakaryocyte proliferation in the bone marrow 
A)  A self-renewing HSC in the AGM 
B)  The production of erythroid cells in the liver 
C)  The presence of hemoglobin F in erythroid cells 
D)  Megakaryocyte proliferation in the bone marrow

Question 6

The hematopoietic compartment of the bone marrow contains what components?

Accepted Answer

A)  Connective tissue and stroma 
B)  Hematopoietic cells and stroma 
C)  Tissues and vasculature 
D)  Tissues and stroma 
A)  Connective tissue and stroma 
B)  Hematopoietic cells and stroma 
C)  Tissues and vasculature 
D)  Tissues and stroma

Question 7

The primary site of hematopoiesis in a 4-month-old maturing fetus is:

Accepted Answer

A)  The liver 
B)  The spleen 
C)  The bone marrow 
D)  A lymph node 
A)  The liver 
B)  The spleen 
C)  The bone marrow 
D)  A lymph node

Question 8

Which of the following sets of organs has the capability of extramedullary hematopoiesis?

Accepted Answer

A)  Thymus and lymph nodes 
B)  Thymus and bone marrow 
C)  Liver and spleen 
D)  Liver and bone marrow 
A)  Thymus and lymph nodes 
B)  Thymus and bone marrow 
C)  Liver and spleen 
D)  Liver and bone marrow

Question 9

Splenomegaly as a result of bone marrow failure is indicative of:

Accepted Answer

A)  Liver disease 
B)  Accelerated immune response 
C)  Extramedullary hematopoiesis 
D)  Nuclear asynchrony 
A)  Liver disease 
B)  Accelerated immune response 
C)  Extramedullary hematopoiesis 
D)  Nuclear asynchrony

Question 10

Hypersplenism associated with compensatory hypertrophy of the spleen is associated with:

Accepted Answer

A)  Neoplasms when malignant cells occupy much of the splenic space 
B)  Congestive heart failure 
C)  Liver cirrhosis with portal hypertension 
D)  Infection and inflammatory diseases 
A)  Neoplasms when malignant cells occupy much of the splenic space 
B)  Congestive heart failure 
C)  Liver cirrhosis with portal hypertension 
D)  Infection and inflammatory diseases

Question 11

A hyperplastic marrow can occur with which of the following?

Accepted Answer

A)  Leukemia 
B)  Postchemotherapy 
C)  Anemia 
D)  Oxygen therapy 
A)  Leukemia 
B)  Postchemotherapy 
C)  Anemia 
D)  Oxygen therapy

Question 12

The primary hematopoietic function of the spleen is:

Accepted Answer

A)  Extramedullary hematopoiesis 
B)  Lymphatic drainage 
C)  Culling and pitting 
D)  T cell maturation 
A)  Extramedullary hematopoiesis 
B)  Lymphatic drainage 
C)  Culling and pitting 
D)  T cell maturation

Question 13

Peyer's patches are an example of:

Accepted Answer

A)  Primary lymphoid tissue 
B)  Secondary lymphoid tissue 
C)  Splenic tissue 
D)  Medullary tissue 
A)  Primary lymphoid tissue 
B)  Secondary lymphoid tissue 
C)  Splenic tissue 
D)  Medullary tissue

Question 14

List four causes of a hyperplastic marrow.

Accepted Answer

a. Acute blood loss causes transient ery

Question 15

Acute blood loss can cause bone marrow hyperplasia. What factor determines the ultimate effect of this pathologic state?

Accepted Answer

A)  Ineffective hematopoiesis 
B)  Cause of the blood loss 
C)  Severity and duration of the blood loss 
D)  Bone marrow activity 
A)  Ineffective hematopoiesis 
B)  Cause of the blood loss 
C)  Severity and duration of the blood loss 
D)  Bone marrow activity

Exam 3: Structure and Function of Hematopoietic Organs

Primitive erythropoiesis in the yolk sac is important to what process?

Explain how the bone marrow receives nutrients to survive.

Where in the body does maturation of T lymphocytes take place?

A characteristic that defines a tissue as primary vs. secondary lymphoid tissue is:

Which of the following characterizes definitive erythropoiesis?

The hematopoietic compartment of the bone marrow contains what components?

The primary site of hematopoiesis in a 4-month-old maturing fetus is:

Which of the following sets of organs has the capability of extramedullary hematopoiesis?

Splenomegaly as a result of bone marrow failure is indicative of:

Hypersplenism associated with compensatory hypertrophy of the spleen is associated with:

A hyperplastic marrow can occur with which of the following?

The primary hematopoietic function of the spleen is:

Peyer's patches are an example of:

List four causes of a hyperplastic marrow.

Acute blood loss can cause bone marrow hyperplasia. What factor determines the ultimate effect of this pathologic state?

Introduction

Cellular Homeostasis

Hematopoiesis

The Erythrocyte

Hemoglobin

Granulocytes and Monocytes

Lymphocytes

The Platelet

The Complete Blood Count and Peripheral Blood Smear Evaluation

Introduction to Anemia

Anemias of Disordered Iron Metabolism and Heme Synthesis

Hemoglobinopathies: Qualitative Defects

Thalassemia

Megaloblastic and Nonmegaloblastic Macrocytic Anemias

Hypoproliferative Anemias

Hemolytic Anemia: Membrane Defects

Hemolytic Anemia: Enzyme Deficiencies

Hemolytic Anemia: Immune Anemias

Hemolytic Anemia: Nonimmune Defects

Nonmalignant Disorders of Leukocytes: Granulocytes and Monocytes

Nonmalignant Lymphocyte Disorders

Introduction to Hematopoietic Neoplasms

Myeloproliferative Neoplasms

Myelodysplastic Syndromes

Acute Myeloid Leukemias

Precursor Lymphoid Neoplasms

Mature Lymphoid Neoplasms

Hematopoietic Stem Cell Transplantation

Morphologic Analysis of Body Fluids in the Hematology

Primary Hemostasis

Secondary Hemostasis and Fibrinolysis

Disorders of Primary Hemostasis

Disorders of Secondary Hemostasis

Thrombophilia

Hemostasis: Laboratory Testing and Instrumentation

Hematology Procedures

Bone Marrow Examination

Automation in Hematology

Flow Cytometry

Chromosome Analysis of Hematopoietic and Lymphoid Disorders

Molecular Analysis of Hematologic Diseases

Quality Assessment in the Hematology Laboratory

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