Exam 17: Transcription, Rna Processing, and Translation

a- amanitin is a toxin produced by the death cap mushroom. It blocks the synthesis of mRNA. What effect would it have on health of the organism that ate death cap mushrooms?

David Pribnow studied the base sequences of promoters in bacteria and bacterial viruses. He found two conserved regions in these promoters the - 10 box and the - 35 box). What is the function of these two regions of the promoter?

There should be a strong positive correlation between the rate of protein synthesis and

Figure 17.1 -The enzyme complex associated with DNA in the figure is

Post- translational modifications include all of the following EXCEPT

Which of the following is NOT one of the steps in initiation of translation?

Eukaryotes have three nuclear RNA polymerases. The primary function of RNA polymerase II is

Put the following events of transcription in chronological order. 1) Sigma binds to the promoter region. 2) The double helix of DNA is unwound, breaking hydrogen bonds between complementary strands. 3) Sigma binds to RNA polymerase. 4) Sigma is released. 5) Transcription begins.

During elongation, RNA polymerase has three prominent channels, or grooves. These channels provide sites for all of the following, EXCEPT

Which of the following occurs in prokaryotes, but not eukaryotes?

The start codon is the same for prokaryotes and eukaryotes. What is the start codon?

Which molecule or reaction supplies the energy for polymerization of nucleotides in the process of transcription?

$\text {Genes and RNA transcripts differ in length.}$ Figure 17.2 -Refer to Figure 17.2. The mRNA is smaller than the length of the DNA that codes for it because

A mutant bacterial cell has a defective aminoacyl- tRNA synthetase that attaches a lysine to tRNAs with the anticodon AAA instead of the normal phenylalanine. What would the consequence of this be for the cell?

RNA polymerase needs a subunit to initiate transcription that is not needed for transcript elongation. What is the subunit?

What molecule is responsible for the catalytic activity in the spliceosomes that are involved in removal of introns?

Figure 17.4 -Refer to Figure 17.4. During elongation, which site in the ribosome represents the location where a codon is being read?

Which of the following does not play a role in the process of translation?

A primary transcript in the nucleus of a eukaryotic cell is the functional mRNA, while a primary transcript in a prokaryotic cell is _ the functional mRNA.

Death cap mushrooms produce a substance called - amanitin. a- amanitin efficiently blocks synthesis of mRNA, but not of tRNA or rRNA in eukaryotic organisms. How is that possible?