Question 1

A patient with 8% factor VIII activity has which form of hemophilia?

Accepted Answer

A) Severe 
B) Moderate 
C) Mild 
D) Asymptomatic 
A) Severe 
B) Moderate 
C) Mild 
D) Asymptomatic C

Question 2

Which of the following is not a vitamin K-dependent factor?

Accepted Answer

A) Factor VIII 
B) Factor II 
C) Factor VII 
D) Factor IX 
A) Factor VIII 
B) Factor II 
C) Factor VII 
D) Factor IX A

Question 3

Treatment of patients with factor II, VII, or X deficiency consists of:

Accepted Answer

A) Administration of prothrombin complex concentrate 
B) Administration of cryoprecipitate 
C) Administration of FFP 
D) Administration of whole blood 
A) Administration of prothrombin complex concentrate 
B) Administration of cryoprecipitate 
C) Administration of FFP 
D) Administration of whole blood A

Question 4

Patients with hemophilia A or B have abnormal results in which coagulation assay?

Accepted Answer

A) APTT 
B) PT 
C) Fibrinogen assay 
D) Platelet count 
A) APTT 
B) PT 
C) Fibrinogen assay 
D) Platelet count

Question 5

What is a new treatment alternative for hemophilia patients?

Accepted Answer

A) Recombinant factor VIII 
B) Fresh frozen plasma 
C) Gene therapy 
D) Cryoprecipitate 
A) Recombinant factor VIII 
B) Fresh frozen plasma 
C) Gene therapy 
D) Cryoprecipitate

Question 6

Which of the following is the most prevalent inherited bleeding disorder?

Accepted Answer

A) Hemophilia A 
B) Hemophilia B 
C) Factor VII deficiency 
D) von Willebrand Disease 
A) Hemophilia A 
B) Hemophilia B 
C) Factor VII deficiency 
D) von Willebrand Disease

Question 7

Christmas disease is another name for:

Accepted Answer

A) Hemophilia A 
B) Hemophilia B 
C) von Willebrand's disease 
D) Factor VII deficiency 
A) Hemophilia A 
B) Hemophilia B 
C) von Willebrand's disease 
D) Factor VII deficiency

Question 8

Clotting factors must be present at a minimum of which percentage for hemostasis to be achieved?

Accepted Answer

A) 20% 
B) 30% 
C) 50% 
D) 75% 
A) 20% 
B) 30% 
C) 50% 
D) 75%

Question 9

Keloid scar formation is most commonly associated with:

Accepted Answer

A) Factor VIII deficiency 
B) Factor IX deficiency 
C) Factor XII deficiency 
D) Factor XIII deficiency 
A) Factor VIII deficiency 
B) Factor IX deficiency 
C) Factor XII deficiency 
D) Factor XIII deficiency

Question 10

The following laboratory results have been obtained for a 40-year-old woman with infrequent bleeding: PT = 20 seconds (reference range is 11 to 15 seconds), APTT = 50 seconds (reference range is 22 to 40 seconds).What factor deficiency is most likely?

Accepted Answer

A) VII 
B) VIII 
C) X 
D) XIII 
A) VII 
B) VIII 
C) X 
D) XIII

Question 11

Which of the following assays will be abnormal with hemophilia A?

Accepted Answer

A) Platelet count 
B) Bleeding time 
C) PT 
D) aPTT 
A) Platelet count 
B) Bleeding time 
C) PT 
D) aPTT

Question 12

The treatment of choice for hemophilia A individuals is:

Accepted Answer

A) Cryoprecipitate 
B) Recombinant factor VIII 
C) Prothrombin complex 
D) DDAVP 
A) Cryoprecipitate 
B) Recombinant factor VIII 
C) Prothrombin complex 
D) DDAVP

Question 13

Factor VIII is also known as which?

Accepted Answer

A) X factor 
B) Plasminogen 
C) Christmas factor 
D) Antihemophilic globulin 
A) X factor 
B) Plasminogen 
C) Christmas factor 
D) Antihemophilic globulin

Question 14

A man with hemophilia A and an unaffected female can produce a:

Accepted Answer

A) Female carrier 
B) Male carrier 
C) Male with hemophilia A 
D) Normal female 
A) Female carrier 
B) Male carrier 
C) Male with hemophilia A 
D) Normal female

Question 15

The only clotting factor not synthesized exclusively by the liver is factor:

Accepted Answer

A) V 
B) VII 
C) VIII 
D) IX 
A) V 
B) VII 
C) VIII 
D) IX

Question 16

Long-term antibiotic therapy is a cause of bleeding because it disrupts:

Accepted Answer

A) Vitamin K synthesis 
B) Contact activation 
C) Platelet aggregation 
D) Fibrinolytic activity 
A) Vitamin K synthesis 
B) Contact activation 
C) Platelet aggregation 
D) Fibrinolytic activity

Question 17

All of the following may lead to deficiencies of clotting factors except:

Accepted Answer

A) Renal disease 
B) Liver disease 
C) Autoimmune disease 
D) Cardiovascular disease 
A) Renal disease 
B) Liver disease 
C) Autoimmune disease 
D) Cardiovascular disease

Question 18

Factor assays measure the percentage of activity of a given factor by mixing the patient's plasma with:

Accepted Answer

A) Normal plasma 
B) Adsorbed plasma 
C) Factor-deficient plasma 
D) Factor-specific plasma 
A) Normal plasma 
B) Adsorbed plasma 
C) Factor-deficient plasma 
D) Factor-specific plasma

Question 19

Which of the following is the most useful in differentiating hemophilia A from hemophilia B?

Accepted Answer

A) A familial pattern of inheritance 
B) Patient's history 
C) Activated partial thromboplastin time 
D) Factor assays 
A) A familial pattern of inheritance 
B) Patient's history 
C) Activated partial thromboplastin time 
D) Factor assays

A patient with 8% factor VIII activity has which form of hemophilia?

Which of the following is not a vitamin K-dependent factor?

Treatment of patients with factor II, VII, or X deficiency consists of:

Patients with hemophilia A or B have abnormal results in which coagulation assay?

What is a new treatment alternative for hemophilia patients?

Which of the following is the most prevalent inherited bleeding disorder?

Christmas disease is another name for:

Clotting factors must be present at a minimum of which percentage for hemostasis to be achieved?

Keloid scar formation is most commonly associated with:

The following laboratory results have been obtained for a 40-year-old woman with infrequent bleeding: PT = 20 seconds (reference range is 11 to 15 seconds), APTT = 50 seconds (reference range is 22 to 40 seconds).What factor deficiency is most likely?

Which of the following assays will be abnormal with hemophilia A?

The treatment of choice for hemophilia A individuals is:

Factor VIII is also known as which?

A man with hemophilia A and an unaffected female can produce a:

The only clotting factor not synthesized exclusively by the liver is factor:

Long-term antibiotic therapy is a cause of bleeding because it disrupts:

All of the following may lead to deficiencies of clotting factors except:

Factor assays measure the percentage of activity of a given factor by mixing the patient's plasma with:

Which of the following is the most useful in differentiating hemophilia A from hemophilia B?

Introduction to Hematology and Basic Laboratory Practice

From Hematopoiesis to the Complete Blood Count

Blood Cell Production and Function and Relevant Red Cell Morphology

Hemoglobin Function and Principles of Hemolysis

The Microcytic Anemias

The Macrocytic Anemias

Normochromic Anemias: Biochemical and Membrane Disorders and Miscellaneous Red Cell Disorders

The Normochromic Anemias Due to Hemoglobinopathies

Leukopoiesis and Leukopoietic Function

Abnormalities of White Cells: Quantitative, Qualitative, and the Lipid Storage Diseases

Acute Leukemias

Myeloproliferative Neoplasms

Lymphoproliferative Disorders and Related Plasma Cell Disorders

The Myelodysplastic Syndromes

Overview of Hemostasis and Platelet Physiology

Quantitative and Qualitative Platelet Disorders

Fibrinogen, Thrombin, and the Fibrinolytic System

Introduction to Thrombosis and Anticoagulant Therapy

Hematology Automation and Flow Cell Cytometry

Filters

Exam 17: Defects of Plasma Clotting Factors

A patient with 8% factor VIII activity has which form of hemophilia?

Which of the following is not a vitamin K-dependent factor?

Treatment of patients with factor II, VII, or X deficiency consists of:

Patients with hemophilia A or B have abnormal results in which coagulation assay?

What is a new treatment alternative for hemophilia patients?

Which of the following is the most prevalent inherited bleeding disorder?

Christmas disease is another name for:

Clotting factors must be present at a minimum of which percentage for hemostasis to be achieved?

Keloid scar formation is most commonly associated with:

The following laboratory results have been obtained for a 40-year-old woman with infrequent bleeding: PT = 20 seconds (reference range is 11 to 15 seconds), APTT = 50 seconds (reference range is 22 to 40 seconds).What factor deficiency is most likely?

Which of the following assays will be abnormal with hemophilia A?

The treatment of choice for hemophilia A individuals is:

Factor VIII is also known as which?

A man with hemophilia A and an unaffected female can produce a:

The only clotting factor not synthesized exclusively by the liver is factor:

Long-term antibiotic therapy is a cause of bleeding because it disrupts:

All of the following may lead to deficiencies of clotting factors except:

Factor assays measure the percentage of activity of a given factor by mixing the patient's plasma with:

Which of the following is the most useful in differentiating hemophilia A from hemophilia B?

Introduction to Hematology and Basic Laboratory Practice

From Hematopoiesis to the Complete Blood Count

Blood Cell Production and Function and Relevant Red Cell Morphology

Hemoglobin Function and Principles of Hemolysis

The Microcytic Anemias

The Macrocytic Anemias

Normochromic Anemias: Biochemical and Membrane Disorders and Miscellaneous Red Cell Disorders

The Normochromic Anemias Due to Hemoglobinopathies

Leukopoiesis and Leukopoietic Function

Abnormalities of White Cells: Quantitative, Qualitative, and the Lipid Storage Diseases

Acute Leukemias

Myeloproliferative Neoplasms

Lymphoproliferative Disorders and Related Plasma Cell Disorders

The Myelodysplastic Syndromes

Overview of Hemostasis and Platelet Physiology

Quantitative and Qualitative Platelet Disorders

Fibrinogen, Thrombin, and the Fibrinolytic System

Introduction to Thrombosis and Anticoagulant Therapy

Hematology Automation and Flow Cell Cytometry

Filters