Question 1

At a minimum, all but which of the following must be included on the tissue receipt records?

Accepted Answer

A)  Tissue Identification Number (TIN) 
B)  Expiration date (if applicable) 
C)  Condition of the tissue and who received it/inspected it upon arrival 
D)  Donor's birth date 
A)  Tissue Identification Number (TIN) 
B)  Expiration date (if applicable) 
C)  Condition of the tissue and who received it/inspected it upon arrival 
D)  Donor's birth date D

Question 2

According to the AABB, what is the function of the medical director with regard to tissue banks?

Accepted Answer

A)  Must obtain special education and approves standard operating procedures 
B)  Investigates adverse outcomes and participates in look-back investigations 
C)  Communicates with the physicians using the procured tissue or end product 
D)  All of these 
A)  Must obtain special education and approves standard operating procedures 
B)  Investigates adverse outcomes and participates in look-back investigations 
C)  Communicates with the physicians using the procured tissue or end product 
D)  All of these D

Question 3

From which organization would a newly established tissue bank seek accreditation?

Accepted Answer

A)  American Association of Tissue Banks 
B)  The Food and Drug Administration 
C)  The Joint Commission 
D)  Any of these 
A)  American Association of Tissue Banks 
B)  The Food and Drug Administration 
C)  The Joint Commission 
D)  Any of these A

Question 4

What steps can be taken to minimize adverse events due to transplantation?

Accepted Answer

A)  Ensuring contaminated tissues are not used for transplantation 
B)  Preventing improper handling that may contaminate or damage tissue 
C)  Demonstration of safety and effectiveness of tissue products 
D)  All of these 
A)  Ensuring contaminated tissues are not used for transplantation 
B)  Preventing improper handling that may contaminate or damage tissue 
C)  Demonstration of safety and effectiveness of tissue products 
D)  All of these

Question 5

The Joint Commission's standard states that

Accepted Answer

A)  hospitals are required to establish a specific tissue bank. 
B)  hospital tissue banks must be located within the blood bank. 
C)  oversight of the tissue bank must be assigned. 
D)  all of these must be followed. 
A)  hospitals are required to establish a specific tissue bank. 
B)  hospital tissue banks must be located within the blood bank. 
C)  oversight of the tissue bank must be assigned. 
D)  all of these must be followed.

Question 6

Which of these organizations is NOT involved with tissue bank regulating?

Accepted Answer

A)  American Association of Tissue Banks 
B)  American Society of Clinical Pathology 
C)  The Food and Drug Administration 
D)  The Joint Commission 
A)  American Association of Tissue Banks 
B)  American Society of Clinical Pathology 
C)  The Food and Drug Administration 
D)  The Joint Commission

Question 7

Which Joint Commission standard has to do with storage of tissues?

Accepted Answer

A)  PC.17.10 
B)  PC.17.20 
C)  PC.17.30 
D)  All of the above 
A)  PC.17.10 
B)  PC.17.20 
C)  PC.17.30 
D)  All of the above

Question 8

Which of these occurrences might initiate a recall?

Accepted Answer

A)  An error in tissue processing is discovered 
B)  FDA inspection uncovers an irregularity in tissue processing. 
C)  A doctor discovers a tissue handling problem. 
D) All of these 
A)  An error in tissue processing is discovered 
B)  FDA inspection uncovers an irregularity in tissue processing. 
C)  A doctor discovers a tissue handling problem. 
D) All of these

Question 9

The following are of concern when selecting a qualified tissue vendor EXCEPT:

Accepted Answer

A)  the transparency and willingness of the vendor to provide information. 
B)  the method of processing and disinfecting the tissue. 
C)  the supplier's medical director staying out of the communication loop. 
D)  the ability of the supplier to meet special needs. 
A)  the transparency and willingness of the vendor to provide information. 
B)  the method of processing and disinfecting the tissue. 
C)  the supplier's medical director staying out of the communication loop. 
D)  the ability of the supplier to meet special needs.

Question 10

Which of these events are classified as adverse?

Accepted Answer

A)  Infectious disease transmission. 
B)  Failure of the allograft to function as expected 
C)  Transmission of malignancy 
D)  All of these 
A)  Infectious disease transmission. 
B)  Failure of the allograft to function as expected 
C)  Transmission of malignancy 
D)  All of these

Question 11

Tissue receipt records do not require which of the following data?

Accepted Answer

A)  Date of tissue collection of tissue 
B)  Name and address of tissue supplier 
C)  Description of tissue and quantity 
D)  Date of tissue received at the facility 
A)  Date of tissue collection of tissue 
B)  Name and address of tissue supplier 
C)  Description of tissue and quantity 
D)  Date of tissue received at the facility

Question 12

A bone flap is harvested by a physician for a patient at hospital X. The patient has an issue with hospital X and requests to go to hospital Y. The patient is transferred, but the physician wants to continue with the treatment. Which of the following scenarios is possible?

Accepted Answer

A)  Hospital X would need to be registered with the FDA as a tissue vendor in order to transfer the bone flap to hospital Y. 
B)  The patient is allowed to take the bone flap with him to hospital Y because it is autologous. 
C)  The physician is licensed to practice at both hospitals, so he is allowed to transfer the bone flap. 
D)  There is no tissue with transfer from one hospital to the next, because the material being transferred is bone. 
A)  Hospital X would need to be registered with the FDA as a tissue vendor in order to transfer the bone flap to hospital Y. 
B)  The patient is allowed to take the bone flap with him to hospital Y because it is autologous. 
C)  The physician is licensed to practice at both hospitals, so he is allowed to transfer the bone flap. 
D)  There is no tissue with transfer from one hospital to the next, because the material being transferred is bone.

Question 13

Which of the following statements is false?

Accepted Answer

A)  Bone can be sterilized and all living tissue removed prior to its use. 
B)  Bone must be HLA typed to the recipient prior to implantation. 
C)  ABO/RH is not relative to be bone transplantation. 
D)  Bone can be made into screws, chips, spacers, and wedges for patient use. 
A)  Bone can be sterilized and all living tissue removed prior to its use. 
B)  Bone must be HLA typed to the recipient prior to implantation. 
C)  ABO/RH is not relative to be bone transplantation. 
D)  Bone can be made into screws, chips, spacers, and wedges for patient use.

Question 14

Which statement about autologous is true?

Accepted Answer

A)  Autologous tissue has a different outdate than allogeneic tissue. 
B)  Autologous tissue is not regulated by the AATB. 
C)  The medical director can have autologous tissue reassigned to an allogeneic donor if it is not used by the autologous donor. 
D)  Autologous tissue should have the same shelf-life as allogeneic tissue under the same storage. 
A)  Autologous tissue has a different outdate than allogeneic tissue. 
B)  Autologous tissue is not regulated by the AATB. 
C)  The medical director can have autologous tissue reassigned to an allogeneic donor if it is not used by the autologous donor. 
D)  Autologous tissue should have the same shelf-life as allogeneic tissue under the same storage.

Question 15

Which of the following does NOT describe an adverse event.

Accepted Answer

A)  A patient contracts Creutzfeldt-Jakob disease a year after tissue transplantation. 
B)  An allograft is failing to function as expected and appears to be rejected. 
C)  An irregularity with the handling of a particular tissue is discovered in an FDA inspection 3 months after the tissue was processed. 
D)  An infection may have been caused by an improperly handled tissue for transplantation. 
A)  A patient contracts Creutzfeldt-Jakob disease a year after tissue transplantation. 
B)  An allograft is failing to function as expected and appears to be rejected. 
C)  An irregularity with the handling of a particular tissue is discovered in an FDA inspection 3 months after the tissue was processed. 
D)  An infection may have been caused by an improperly handled tissue for transplantation.

Question 16

What must be considered when selecting a qualified tissue vendor?

Accepted Answer

A)  Tissues supplied must be high in quality, safe and effective for the intended use. 
B)  The tissue must be readily available in a useful time frame 
C)  Cost of tissue must fall within budgetary guidelines and customary price range. 
D)  All of these 
A)  Tissues supplied must be high in quality, safe and effective for the intended use. 
B)  The tissue must be readily available in a useful time frame 
C)  Cost of tissue must fall within budgetary guidelines and customary price range. 
D)  All of these

Question 17

The AABB Tissue Committee's recommended model for a centralized tissue bank includes:

Accepted Answer

A)  allowing surgeons to maintain their own inventories. 
B)  validating vendor qualifications being handled by the purchasing department. 
C)  the infectious diseases department investigation of adverse events. 
D)  none of these. 
A)  allowing surgeons to maintain their own inventories. 
B)  validating vendor qualifications being handled by the purchasing department. 
C)  the infectious diseases department investigation of adverse events. 
D)  none of these.

Question 18

Upon periodic inspection of tissue products, a violation of an FDA labeling regulation is discovered. What class of recall would this initiate?

Accepted Answer

A)  Class I 
B)  Class II 
C)  Class III 
D)  None 
A)  Class I 
B)  Class II 
C)  Class III 
D)  None

Question 19

Which of the following is generally excluded from the tissue bank?

Accepted Answer

A)  Corneas 
B)  Liver 
C)  Heart valves 
D)  Skin 
A)  Corneas 
B)  Liver 
C)  Heart valves 
D)  Skin

Question 20

The 21 in 21 CFR 1271 refers to:

Accepted Answer

A)  the region from which the tissue was collected, thus falling under the general provisions of that area. 
B)  the title established for food and drugs in the Code of Federal Regulations. 
C)  the category of FDA laws that govern all blood bank regulation. 
D)  none of the above. 
A)  the region from which the tissue was collected, thus falling under the general provisions of that area. 
B)  the title established for food and drugs in the Code of Federal Regulations. 
C)  the category of FDA laws that govern all blood bank regulation. 
D)  none of the above.

Exam 22: Tissue Banking As Part of the Transfusion Service

At a minimum, all but which of the following must be included on the tissue receipt records?

According to the AABB, what is the function of the medical director with regard to tissue banks?

From which organization would a newly established tissue bank seek accreditation?

What steps can be taken to minimize adverse events due to transplantation?

The Joint Commission's standard states that

Which of these organizations is NOT involved with tissue bank regulating?

Which Joint Commission standard has to do with storage of tissues?

Which of these occurrences might initiate a recall?

The following are of concern when selecting a qualified tissue vendor EXCEPT:

Which of these events are classified as adverse?

Tissue receipt records do not require which of the following data?

A bone flap is harvested by a physician for a patient at hospital X. The patient has an issue with hospital X and requests to go to hospital Y. The patient is transferred, but the physician wants to continue with the treatment. Which of the following scenarios is possible?

Which of the following statements is false?

Which statement about autologous is true?

Which of the following does NOT describe an adverse event.

What must be considered when selecting a qualified tissue vendor?

The AABB Tissue Committee's recommended model for a centralized tissue bank includes:

Upon periodic inspection of tissue products, a violation of an FDA labeling regulation is discovered. What class of recall would this initiate?

Which of the following is generally excluded from the tissue bank?

The 21 in 21 CFR 1271 refers to:

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The Rh Blood Group System

Blood Group Terminology and Common Blood Groups

Uncommon Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Blood Bank Technologies and Automation

Donor Selection

Transfusion-Transmitted Diseases

Component Preparation

Transfusion Therapy

Adverse Effects of Blood Transfusion

Apheresis

Cellular Therapy in the Transplant Setting

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

The Hla System

Relationship Testing

Quality Management

Patient Blood Management

Transfusion Safety and Federal Regulatory Requirements

Laboratory Information Systems in the Blood Bank

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

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