Question 1

What are platelets obtained from apheresis donations called?

Accepted Answer

A)  Random-donor platelets (RDPs) 
B)  Single-donor platelets (SDPs) 
C)  Targeted-donor platelets (TDPs) 
D)  None of these 
A)  Random-donor platelets (RDPs) 
B)  Single-donor platelets (SDPs) 
C)  Targeted-donor platelets (TDPs) 
D)  None of these B

Question 2

What is the shelf-life of frozen RBCs?

Accepted Answer

A)  1 year 
B)  5 years 
C)  10 years 
D)  Indefinite 
A)  1 year 
B)  5 years 
C)  10 years 
D)  Indefinite C

Question 3

Liquid plasma is prepared from a unit of whole blood collected in CPDA-1 on July 28th. What is the expiration date of this plasma?

Accepted Answer

A)  August 18th 
B)  August 23rd 
C)  September 2nd 
D)  September 7th 
A)  August 18th 
B)  August 23rd 
C)  September 2nd 
D)  September 7th D

Question 4

Normally what percentage of 35-day-old red blood cells should be circulating 24 hours after transfusion?

Accepted Answer

A)  100% 
B)  50% 
C)  65% 
D)  70% 
A)  100% 
B)  50% 
C)  65% 
D)  70%

Question 5

What is the shelf-life for plasma protein fraction?

Accepted Answer

A)  3 years 
B)  5 years 
C)  10 years 
D)  15 years 
A)  3 years 
B)  5 years 
C)  10 years 
D)  15 years

Question 6

What is the expiration time for platelet concentrates that have been pooled?

Accepted Answer

A)  24 hours 
B)  6 hours 
C)  4 hours 
D)  48 hours 
A)  24 hours 
B)  6 hours 
C)  4 hours 
D)  48 hours

Question 7

All of the following statements are characteristic of a penetrating cryoprotective agent except:

Accepted Answer

A)  it consists of generally small molecules. 
B)  osmotic force prevents migration of water outside of the cell, preventing dehydration. 
C)  large molecules form a shell around the cell, preventing loss of water and dehydration. 
D)  none of the above. 
A)  it consists of generally small molecules. 
B)  osmotic force prevents migration of water outside of the cell, preventing dehydration. 
C)  large molecules form a shell around the cell, preventing loss of water and dehydration. 
D)  none of the above.

Question 8

Manufacturing RDPs is accomplished by using all of the following methods EXCEPT:

Accepted Answer

A)  apheresis collection. 
B)  buffy coat aspiration. 
C)  centrifuge on high 
D)  centrifuge on low. 
A)  apheresis collection. 
B)  buffy coat aspiration. 
C)  centrifuge on high 
D)  centrifuge on low.

Question 9

Which of the follow does NOT describe the preparation of NSA?

Accepted Answer

A)  Plasma is salvaged and pooled. 
B)  Plasma is fractionated using a warm alcohol process. 
C)  HIV and hepatitis are inactivated with heat inactivation. 
D)  NSA composition includes of 96% albumin and 4% globulin. 
A)  Plasma is salvaged and pooled. 
B)  Plasma is fractionated using a warm alcohol process. 
C)  HIV and hepatitis are inactivated with heat inactivation. 
D)  NSA composition includes of 96% albumin and 4% globulin.

Question 10

Which statement about liquid plasma is correct?

Accepted Answer

A)  Liquid plasma is a product from whole blood donations. 
B)  The expiration of liquid plasma is 5 days after its whole blood shelf-life. 
C)  Liquid plasma is stored at 1° to 6°C. 
D)  All of these are correct. 
A)  Liquid plasma is a product from whole blood donations. 
B)  The expiration of liquid plasma is 5 days after its whole blood shelf-life. 
C)  Liquid plasma is stored at 1° to 6°C. 
D)  All of these are correct.

Question 11

Which of the following are approved preservative solutions for blood storage at 1°C to 6°C for 21 days?

Accepted Answer

A)  ACD 
B)  CPD 
C)  CP2D 
D)  All of the above 
A)  ACD 
B)  CPD 
C)  CP2D 
D)  All of the above

Question 12

What is the half-life of immune serum globulin?

Accepted Answer

A)  3 to 7 days 
B)  10 to 15 days 
C)  18 to 32 days 
D)  40 to 45 days 
A)  3 to 7 days 
B)  10 to 15 days 
C)  18 to 32 days 
D)  40 to 45 days

Question 13

Methods of preparation of platelet concentrates from single units of whole blood must produce a product that yields a minimum of:

Accepted Answer

A)  5.5 $\times$ 1011 platelets per unit in 50% of units tested. 
B)  5.5 $\times$ 1011 platelets per unit in 75% of units tested. 
C)  5.5 $\times$ 1010 platelets per unit in 75% of units tested. 
D)  none of the above. 
A)  5.5 $\times$ 1011 platelets per unit in 50% of units tested. 
B)  5.5 $\times$ 1011 platelets per unit in 75% of units tested. 
C)  5.5 $\times$ 1010 platelets per unit in 75% of units tested. 
D)  none of the above.

Question 14

Which of the following is/are an example of a penetrating cryoprotective agent?

Accepted Answer

A)  Dimethylsulfoxide 
B)  Glycerol 
C)  Hydroxyethyl starch 
D)  All of these 
A)  Dimethylsulfoxide 
B)  Glycerol 
C)  Hydroxyethyl starch 
D)  All of these

Question 15

Plasma factor concentrates are separated into various proteins by manipulating which variable?

Accepted Answer

A)  pH 
B)  Alcohol content 
C)  Temperature 
D)  All of these 
A)  pH 
B)  Alcohol content 
C)  Temperature 
D)  All of these

Question 16

Units of platelets are stored under which of these conditions?

Accepted Answer

A)  Constant agitation 
B)  Darkened chamber 
C)  Hanging from a hook 
D)  None of these 
A)  Constant agitation 
B)  Darkened chamber 
C)  Hanging from a hook 
D)  None of these

Question 17

A unit of cryopreserved RBCs must be stored below what temperature?

Accepted Answer

A)  -80°C 
B)  -65°C 
C)  -20°C 
D)  0°C 
A)  -80°C 
B)  -65°C 
C)  -20°C 
D)  0°C

Question 18

What is the minimal pH required for platelets?

Accepted Answer

A)  6.0 
B)  6.2 
C)  7.0 
D)  7.2 
A)  6.0 
B)  6.2 
C)  7.0 
D)  7.2

Question 19

A whole blood donation contains a volume of 350 mL. Which of the following is true regarding this unit?

Accepted Answer

A)  Packed red blood cells cannot be made from this unit. 
B)  FFP cannot be made from this unit. 
C)  Cryoprecipitate can be made from this unit. 
D)  Platelets cannot be made from this unit. 
A)  Packed red blood cells cannot be made from this unit. 
B)  FFP cannot be made from this unit. 
C)  Cryoprecipitate can be made from this unit. 
D)  Platelets cannot be made from this unit.

Question 20

What is the shelf life of whole blood collected in acid-citrate-dextrose?

Accepted Answer

A)  10 days 
B)  21 days 
C)  35 days 
D)  50 days 
A)  10 days 
B)  21 days 
C)  35 days 
D)  50 days

Exam 15: Component Preparation

What are platelets obtained from apheresis donations called?

What is the shelf-life of frozen RBCs?

Liquid plasma is prepared from a unit of whole blood collected in CPDA-1 on July 28th. What is the expiration date of this plasma?

Normally what percentage of 35-day-old red blood cells should be circulating 24 hours after transfusion?

What is the shelf-life for plasma protein fraction?

What is the expiration time for platelet concentrates that have been pooled?

All of the following statements are characteristic of a penetrating cryoprotective agent except:

Manufacturing RDPs is accomplished by using all of the following methods EXCEPT:

Which of the follow does NOT describe the preparation of NSA?

Which statement about liquid plasma is correct?

Which of the following are approved preservative solutions for blood storage at 1°C to 6°C for 21 days?

What is the half-life of immune serum globulin?

Methods of preparation of platelet concentrates from single units of whole blood must produce a product that yields a minimum of:

Which of the following is/are an example of a penetrating cryoprotective agent?

Plasma factor concentrates are separated into various proteins by manipulating which variable?

Units of platelets are stored under which of these conditions?

A unit of cryopreserved RBCs must be stored below what temperature?

What is the minimal pH required for platelets?

A whole blood donation contains a volume of 350 mL. Which of the following is true regarding this unit?

What is the shelf life of whole blood collected in acid-citrate-dextrose?

Red Blood Cells and Platelet Preservation: Historical Perspectives and Current Trends

Basic Genetics

Fundamentals of Immunology

Concepts in Molecular Biology

The Antiglobulin Test

The Abo Blood Group System

The Rh Blood Group System

Blood Group Terminology and Common Blood Groups

Uncommon Blood Groups

Detection and Identification of Antibodies

Pre-Transfusion Testing

Blood Bank Technologies and Automation

Donor Selection

Transfusion-Transmitted Diseases

Transfusion Therapy

Adverse Effects of Blood Transfusion

Apheresis

Cellular Therapy in the Transplant Setting

Hemolytic Disease of the Fetus and Newborn

Autoimmune Hemolytic Anemias

Tissue Banking As Part of the Transfusion Service

The Hla System

Relationship Testing

Quality Management

Patient Blood Management

Transfusion Safety and Federal Regulatory Requirements

Laboratory Information Systems in the Blood Bank

Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services

Filters

Liquid plasma is prepared from a unit of whole blood collected in CPDA-1 on July 28^th. What is the expiration date of this plasma?