Exam 16: Comparing Two Means

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A study randomly assigned 60 adults diagnosed with metabolic syndrome to two groups, each containing 30 patients. One group was given daily tablets containing the Chinese herbal supplement Yiqi Huaju Qingli, while the other group was given daily placebo tablets. All 60 patients maintained their standard medical treatment throughout the 12 weeks of the study. Urinary microalbumin is a key factor in metabolic syndrome and an early sign of diabetic nephropathy. Urinary microalbumin (in mg/l) was assessed for all participants at the beginning and at the end of the study. Here are the published findings, expressed as "mean (standard deviation)": Herbal Supplement Placebo Start of study 101.58(75.39) 98.50(66.92) End of study 47.11(27.85) 78.87(60.65) Is there evidence that urinary microalbumin differed significantly between the two groups at the start of the study? Based on the data, what is the absolute numerical value of the t statistic for the appropriate test?

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Researchers measured the amount of plasma carotenoids (in micrograms per milliliter) of male and female zebra finches. Here are the summary statistics from the study: Sex Mean Standard Error Males 50 31.77 1.85 Females 52 29.74 2.02 Do male and female zebra finches differ in their plasma carotenoid levels? To answer this question, the researchers tested the following hypotheses: ? H0: ?M=?F versus ?M??F What can we conclude at significance level 5%?

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A new diet has been developed for raising beef cows. Two random samples of size 9 are independently selected, and one is given the standard diet while the other is given the new diet. After 18 weeks, the weight gain was measured for each cow. It was found that x̄1= 30 with S1= 8 and x̄2= 26 with S2= 6. Let μ1 and μ2 represent the mean weight gains we would observe for the entire population of beef cows when on, respectively, a new diet and a standard diet. Assume that two-sample t procedures are safe to use. Suppose the researcher had wished to test the following hypotheses: H0: μ1 = μ2 versus Ha: μ1 > μ2 What is the P-value for the test of these hypotheses?

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Researchers examined the bill color (in hue degree) of male and female zebra finches. Here are some summary statistics from the study: Sex Mean Standard Error Males 59 2.91 0.19 Females 60 7.42 0.32 We wish to address the question, How different are male and female zebra finches in bill color? What is a 95% confidence interval for the difference in mean bill color ?F-?M (in hue degree)?

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The circumference of a species of tree was thought to be different depending on certain geographical factors. An SRS of 60 trees of this species is selected in Sequoyah National Forest, where it is found that x̄1= 6 meters with a standard deviation S1= 3 meters. A second SRS of size 40 trees of the same species is independently selected in Yellowstone National Forest, and it is found that x̄2= 4 meters with a standard deviation S2= 2 meters. Let μ1 and μ2 represent, respectively, the true mean circumferences of this species of tree. Assume the two-sample t procedures are safe to use. What is a 95% confidence interval for μ1 - μ2 based on these data?

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A study randomly assigned 60 adults diagnosed with metabolic syndrome to two groups, each containing 30 patients. One group was given daily tablets containing the Chinese herbal supplement Yiqi Huaju Qingli, while the other group was given daily placebo tablets. All 60 patients maintained their standard medical treatment throughout the 12 weeks of the study. Urinary microalbumin is a key factor in metabolic syndrome and an early sign of diabetic nephropathy. Urinary microalbumin (in mg/l) was assessed for all participants at the beginning and at the end of the study. Here are the published findings, expressed as "mean (standard deviation)": ? Herbal Supplement Placebo Start of study 101.58(75.39) 98.50(66.92) End of study 47.11(27.85) 78.87(60.65) Using significance level ?= 0.05, do the data provide evidence that urinary microalbumin is significantly lower in the herbal group than in the placebo group at the end of the study? [Note that the degrees of freedom is roughly 40 for this test.]

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A study randomly assigned 60 adults diagnosed with metabolic syndrome to two groups. One group was given daily tablets containing the Chinese herbal supplement Yiqi Huaju Qingli, while the other group was given daily placebo tablets. All 60 patients maintained their standard medical treatment throughout the 12 weeks of the study. Urinary microalbumin (in mg/l) was assessed for all participants at the beginning and at the end of the study. Urinary microalbumin is a key factor in metabolic syndrome and an early sign of diabetic nephropathy. The researchers also wanted to see if urinary microalbumin was significantly lower after 12 weeks in the herbal supplement group. To answer this question, which hypothesis test should the researchers use?

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Some chronic conditions produce episodes of severe flare-ups ("active" stage) between healthy periods ("inactive" stage). The active stage often necessitates immediate medical treatment. Researchers looked for biomarkers that might help identify these active stages. Here are data on the relative abundance of the protein BPG0199 in two independent random samples of men with the same chronic condition, 7 men in the active phase and 9 men in the inactive phase: Active Inactive 2.6 1.2 2.7 2.1 2.0 1.8 2.4 1.5 1.9 1.9 1.4 3.2 1.8 1.3 1.9 1.6 We want to know if there is a significant difference in the relative abundance of the protein BPG0199 between men in the active stage and men in the inactive phase. Therefore, we test the following hypotheses: ? H0: ?A= ?1 versus Ha: ?A? ?1 Which assumption must be TRUE for this test result to be correct?

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A study examined the effect of protein consumption on weight gain in rats. Investigators obtained 14 female rats and randomly assigned 7 of them to a low-protein diet and the other 7 in a high-protein diet. After 60 days, the weight gained by each rat was recorded (in grams). Here are the summary findings, displayed as "mean (standard deviation)": Low-Protein Diet High-Protein Diet 101.3(20.6) 127.5(21.1) Researchers want to know if the amount of protein in the rats' diet significantly affects their weight gain. Based on the data, what is the absolute numerical value of t statistic for the appropriate test?

(Multiple Choice)
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A new diet has been developed for raising beef cows. Two random samples of size 9 are independently selected, and one is given the standard diet while the other is given the new diet. After 18 weeks, the weight gain was measured for each cow. It was found that x̄1= 30 with S1= 8 and x̄2= 26 with S2= 6. Let μ1 and μ2 represent the mean weight gains we would observe for the entire population of beef cows when on, respectively, a new diet and a standard diet. Assume that two-sample t procedures are safe to use. About which of the following characteristics would it have been most important that the researchers be blind during the experiment?

(Multiple Choice)
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Some chronic conditions produce episodes of severe flare-ups ("active" stage) between healthy periods ("inactive" stage). The active stage often necessitates immediate medical treatment. Researchers looked for biomarkers that might help identify these active stages. Here are data on the relative abundance of the protein BPG0235 in two independent random samples of men with the same chronic condition, 7 men in the active phase and 9 men in the inactive phase: Active Inactive 1.0 1.1 1.0 0.9 1.0 0.5 1.2 0.9 1.2 1.0 1.3 1.0 1.0 0.8 0.7 1.1 We want to know if there is a significant difference in the relative abundance of the protein BPG0235 between men in the active stage and men in the inactive phase. Therefore, we test the following hypotheses: ? H0: ?A= ?1 versus Ha: ?A? ?1 What is the absolute numerical value of the two-sample t statistic?

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A large P-value implies that H0 is necessarily true,

(True/False)
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Which of the following procedures is NOT robust to non-Normality?

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Researchers measured the amount of plasma carotenoids (in micrograms per milliliter) of male and female zebra finches. Here are the summary statistics from the study: Sex Mean Standard Error Males 50 31.77 1.85 Females 52 29.74 2.02 Do male and female zebra finches differ in their plasma carotenoid levels? To answer this question, the researchers tested the following hypotheses: ? H0: ?M=?F versus ?M??F What is the numerical value of the two-sample t statistic?

(Multiple Choice)
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Researchers measured the amount of plasma carotenoids (in micrograms per milliliter) of male and female zebra finches. Here are the summary statistics from the study: Sex Mean Standard Error Males 50 31.77 1.85 Females 52 29.74 2.02 Do male and female zebra finches differ in their plasma carotenoid levels? To answer this question, the researchers tested the following hypotheses: ? H0: ?M=?F versus ?M??F What is the P-value for the test?

(Multiple Choice)
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Some chronic conditions produce episodes of severe flare-ups ("active" stage) between healthy periods ("inactive" stage). The active stage often necessitates immediate medical treatment. Researchers looked for biomarkers that might help identify these active stages. Here are data on the relative abundance of the protein BPG0199 in two independent random samples of men with the same chronic condition, 7 men in the active phase and 9 men in the inactive phase: Active Inactive 2.6 1.2 2.7 2.1 2.0 1.8 2.4 1.5 1.9 1.9 1.4 3.2 1.8 1.3 1.9 1.6 We want to know if there is a significant difference in the relative abundance of the protein BPG0199 between men in the active stage and men in the inactive phase. Therefore, we test the following hypotheses: ? H0: ?A= ?1 versus Ha: ?A? ?1 The test degrees of freedom is roughly 13. Which value is the P-value for the test closest to?

(Multiple Choice)
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Researchers are interested in whether the effects of DDT poisoning in rats are less extreme in males. An SRS of 100 male rats and an independent SRS of 100 female rats are obtained. The male rats had a sample mean of 39 and a sample standard deviation of 8. The female rats had a sample mean of 40 and a standard deviation of 10. Let μ1 represent the true mean response for the males and μ2 represent the true mean response of the females. A 95% confidence interval for the difference in true mean response μ1 - μ2 is found to be ( _ 3.53, 1.53). What can we conclude?

(Multiple Choice)
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A study examined the effect of protein consumption on weight gain in rats. Investigators obtained 14 female rats and randomly assigned 7 of them to a low-protein diet and the other 7 in a high-protein diet. After 60 days, the weight gained by each rat was recorded (in grams). Here are the summary findings, displayed as "mean (standard deviation)": Low-Protein Diet High-Protein Diet 101.3(20.6) 127.5(21.1) Given that the degrees of freedom for the appropriate t procedure is approximately 12, what is a 95% confidence interval for ?High - ?Low?

(Multiple Choice)
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Researchers are interested in whether the effects of DDT poisoning in rats are less extreme in males. An SRS of 100 male rats and an independent SRS of 100 female rats are obtained. The male rats had a sample mean of 39 and a sample standard deviation of 8. The female rats had a sample mean of 40 and a standard deviation of 10. Let μ1 represent the true mean response for the males and μ2 represent the true mean response of the females. Which hypothesis should be tested?

(Multiple Choice)
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The circumference of a species of tree was thought to be different depending on certain geographical factors. An SRS of 60 trees of this species is selected in Sequoyah National Forest, where it is found that x̄1= 6 meters with a standard deviation S1= 3 meters. A second SRS of size 40 trees of the same species is independently selected in Yellowstone National Forest, and it is found that x̄2= 4 meters with a standard deviation S2= 2 meters. Let μ1 and μ2 represent, respectively, the true mean circumferences of this species of tree. Assume the two-sample t procedures are safe to use. The researcher tests the following hypotheses: H0: μ1 = μ2 versus Ha: μ1 ≠ μ2 What is the P-value for the test of these hypotheses?

(Multiple Choice)
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