Question 1

If Drug Y passively diffused more effectively than Drug Z in a local environment with a pH of 3,what should be concluded?

Accepted Answer

A)  Drug Y produced more ionized molecules than Drug Z 
B)  The administration route for Drug Y was more effective than Drug Z. 
C)  The pKa value of Drug Y was closer to 3 than the pKa of Drug Z. 
D)  The local environment had a large surface area 
A)  Drug Y produced more ionized molecules than Drug Z 
B)  The administration route for Drug Y was more effective than Drug Z. 
C)  The pKa value of Drug Y was closer to 3 than the pKa of Drug Z. 
D)  The local environment had a large surface area

Question 2

What effect will the monoamine oxidase inhibitor moclobemide have a norepinephrine?

Accepted Answer

A)  Increase norepinephrine concentrations by increasing synthesis. 
B)  Reduce the amount of amount of norepinephrine released into the synaptic cleft. 
C)  Increase norepinephrine concentrations by preventing catabolism of norepinephrine. 
D)  Reduce norepinephrine release by affecting exocytosis. 
A)  Increase norepinephrine concentrations by increasing synthesis. 
B)  Reduce the amount of amount of norepinephrine released into the synaptic cleft. 
C)  Increase norepinephrine concentrations by preventing catabolism of norepinephrine. 
D)  Reduce norepinephrine release by affecting exocytosis.

Question 3

Preventing a neuron's nerve impulses to stop neurotransmitter synthesis.

Accepted Answer

A) True 
 B)False

Question 4

What effect would a drug that blocks a membrane transporter for a neurotransmitter likely have?

Accepted Answer

A)  Increased synthesis of the neurotransmitter 
B)  Increased storage of neurotransmitters in vesicles 
C)  Increased levels of the neurotransmitter in the synaptic cleft 
D)  Increased release of the neurotransmitter 
A)  Increased synthesis of the neurotransmitter 
B)  Increased storage of neurotransmitters in vesicles 
C)  Increased levels of the neurotransmitter in the synaptic cleft 
D)  Increased release of the neurotransmitter

Question 5

The process of _____________ consists of the attachment of a molecule onto a metabolite.

Accepted Answer

A)  conjugation 
B)  biotransformation 
C)  first-pass metabolism 
D)  active transport 
A)  conjugation 
B)  biotransformation 
C)  first-pass metabolism 
D)  active transport

Question 6

A noncompetitive antagonist will do all of the following except:

Accepted Answer

A)  prevent a neurotransmitter from activating a receptor. 
B)  prevent a neurotransmitter from binding to receptor. 
C)  bind to a site different from the neurotransmitter binding site. 
D)  fail to cause a conformation change in the receptor. 
A)  prevent a neurotransmitter from activating a receptor. 
B)  prevent a neurotransmitter from binding to receptor. 
C)  bind to a site different from the neurotransmitter binding site. 
D)  fail to cause a conformation change in the receptor.

Question 7

Most active metabolites are produced from Phase II biotransformation.

Accepted Answer

A) True 
 B)False

Question 8

Which of the following approaches might a pharmacologist take in order to decrease neurotransmission for a particular neurotransmitter?

Accepted Answer

A)  Develop a drug to block membrane transporters. 
B)  Develop a drug to increase neurotransmitter synthesis. 
C)  Develop a drug to block postsynaptic receptors. 
D)  Develop a drug to block autoreceptors. 
A)  Develop a drug to block membrane transporters. 
B)  Develop a drug to increase neurotransmitter synthesis. 
C)  Develop a drug to block postsynaptic receptors. 
D)  Develop a drug to block autoreceptors.

Question 9

________________ is the process by which a drug leaves the body.

Accepted Answer

A)  Elimination 
B)  Biotransformation 
C)  Distribution 
D)  Absorption 
A)  Elimination 
B)  Biotransformation 
C)  Distribution 
D)  Absorption

Question 10

The term "partial agonist" suggests that:

Accepted Answer

A)  the study compound is a mixture of agonists and antagonists. 
B)  behavioral or physiological responses will appear weaker than those produced by a full agonist. 
C)  the drug bound to some receptors but not others. 
D)  a G-protein will only be partly activated. 
A)  the study compound is a mixture of agonists and antagonists. 
B)  behavioral or physiological responses will appear weaker than those produced by a full agonist. 
C)  the drug bound to some receptors but not others. 
D)  a G-protein will only be partly activated.

Question 11

__________________ refers to a drug's strength of binding to a receptor.

Accepted Answer

A)  Binding affinity 
B)  Receptor efficacy 
C)  Agonism 
D)  Antagonism 
A)  Binding affinity 
B)  Receptor efficacy 
C)  Agonism 
D)  Antagonism

Question 12

A disease that caused astrocytes to degenerate would likely:

Accepted Answer

A)  allow pathogens normally blocked by the blood-brain barrier to enter the brain. 
B)  increase the activity of active transport mechanisms. 
C)  cause blood vessels to dilate, increasing cerebral blood flow. 
D)  cause endothelial cells to fit more tightly together. 
A)  allow pathogens normally blocked by the blood-brain barrier to enter the brain. 
B)  increase the activity of active transport mechanisms. 
C)  cause blood vessels to dilate, increasing cerebral blood flow. 
D)  cause endothelial cells to fit more tightly together.

Question 13

Both a competitive and noncompetitive antagonist:

Accepted Answer

A)  allow partial activation of a receptor by an agonist. 
B)  prevent a neurotransmitter from binding to a receptor. 
C)  prevent the activation of a receptor. 
D)  have weak affinities for a receptor. 
A)  allow partial activation of a receptor by an agonist. 
B)  prevent a neurotransmitter from binding to a receptor. 
C)  prevent the activation of a receptor. 
D)  have weak affinities for a receptor.

Question 14

A(n)_____________ has a weaker efficacy for activating receptors than a full agonist.

Accepted Answer

A)  partial agonist 
B)  antagonist 
C)  positive modulator 
D)  competitive antagonist 
A)  partial agonist 
B)  antagonist 
C)  positive modulator 
D)  competitive antagonist

Question 15

_______________ are substances that damage or destroy parts of the nervous system.

Accepted Answer

A)  Protein kinases 
B)  Negative modulators 
C)  Antagonists 
D)  Neurotoxins 
A)  Protein kinases 
B)  Negative modulators 
C)  Antagonists 
D)  Neurotoxins

Question 16

If a study participant were administered 12 μEq/L of a drug in blood.One hour later you found the concentration reduced to 11μEq/L and another hour later you found the concentration reduced to 10μEq/L.Based on these observations,you should conclude:

Accepted Answer

A)  the participant had taken an additional dose of the drug. 
B)  the drug's elimination rate follows first-order kinetics. 
C)  the drug's elimination rate follows zero-order kinetics. 
D)  the participant is a poor metabolizer. 
A)  the participant had taken an additional dose of the drug. 
B)  the drug's elimination rate follows first-order kinetics. 
C)  the drug's elimination rate follows zero-order kinetics. 
D)  the participant is a poor metabolizer.

Question 17

Feeling depressed after time passes since taking a drug that producing rewarding effects would likely be an example of:

Accepted Answer

A)  behavior tolerance. 
B)  sensitization. 
C)  a psychological withdrawal symptom. 
D)  a physical withdrawal symptom. 
A)  behavior tolerance. 
B)  sensitization. 
C)  a psychological withdrawal symptom. 
D)  a physical withdrawal symptom.

Question 18

Withdrawal effects from a drug are an indication of tolerance.

Accepted Answer

A) True 
 B)False

Question 19

List and describe the four primary phases in pharmacokinetics.

Accepted Answer

Absorption refers to the passage of a dr

Question 20

A drug that functions as an agonist is similar to a(n):

Accepted Answer

A)  neurotransmitter. 
B)  receptor. 
C)  positive modulator. 
D)  positively charged ion. 
A)  neurotransmitter. 
B)  receptor. 
C)  positive modulator. 
D)  positively charged ion.

If Drug Y passively diffused more effectively than Drug Z in a local environment with a pH of 3,what should be concluded?

What effect will the monoamine oxidase inhibitor moclobemide have a norepinephrine?

Preventing a neuron's nerve impulses to stop neurotransmitter synthesis.

What effect would a drug that blocks a membrane transporter for a neurotransmitter likely have?

The process of _____________ consists of the attachment of a molecule onto a metabolite.

A noncompetitive antagonist will do all of the following except:

Most active metabolites are produced from Phase II biotransformation.

Which of the following approaches might a pharmacologist take in order to decrease neurotransmission for a particular neurotransmitter?

________________ is the process by which a drug leaves the body.

The term "partial agonist" suggests that:

__________________ refers to a drug's strength of binding to a receptor.

A disease that caused astrocytes to degenerate would likely:

Both a competitive and noncompetitive antagonist:

A(n)_____________ has a weaker efficacy for activating receptors than a full agonist.

_______________ are substances that damage or destroy parts of the nervous system.

If a study participant were administered 12 μEq/L of a drug in blood.One hour later you found the concentration reduced to 11μEq/L and another hour later you found the concentration reduced to 10μEq/L.Based on these observations,you should conclude:

Feeling depressed after time passes since taking a drug that producing rewarding effects would likely be an example of:

Withdrawal effects from a drug are an indication of tolerance.

List and describe the four primary phases in pharmacokinetics.

A drug that functions as an agonist is similar to a(n):

Introduction to Psychopharmacology

The Nervous System

Neurotransmission

Drugs of Abuse

Psychostimulants

Nicotine and Caffeine

Alcohol

GHP and Inhalants

Opioids

Cannabinoids

Psychedelic Drugs

Treatments for Depression and Bipolar Disorder

Treatments for Anxiety Disorders

Antipsychotic Drugs

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Exam 4: Properties of Drugs

If Drug Y passively diffused more effectively than Drug Z in a local environment with a pH of 3,what should be concluded?

What effect will the monoamine oxidase inhibitor moclobemide have a norepinephrine?

Preventing a neuron's nerve impulses to stop neurotransmitter synthesis.

What effect would a drug that blocks a membrane transporter for a neurotransmitter likely have?

The process of _____________ consists of the attachment of a molecule onto a metabolite.

A noncompetitive antagonist will do all of the following except:

Most active metabolites are produced from Phase II biotransformation.

Which of the following approaches might a pharmacologist take in order to decrease neurotransmission for a particular neurotransmitter?

________________ is the process by which a drug leaves the body.

The term "partial agonist" suggests that:

__________________ refers to a drug's strength of binding to a receptor.

A disease that caused astrocytes to degenerate would likely:

Both a competitive and noncompetitive antagonist:

A(n)_____________ has a weaker efficacy for activating receptors than a full agonist.

_______________ are substances that damage or destroy parts of the nervous system.

If a study participant were administered 12 μEq/L of a drug in blood.One hour later you found the concentration reduced to 11μEq/L and another hour later you found the concentration reduced to 10μEq/L.Based on these observations,you should conclude:

Feeling depressed after time passes since taking a drug that producing rewarding effects would likely be an example of:

Withdrawal effects from a drug are an indication of tolerance.

List and describe the four primary phases in pharmacokinetics.

A drug that functions as an agonist is similar to a(n):

Introduction to Psychopharmacology

The Nervous System

Neurotransmission

Drugs of Abuse

Psychostimulants

Nicotine and Caffeine

Alcohol

GHP and Inhalants

Opioids

Cannabinoids

Psychedelic Drugs

Treatments for Depression and Bipolar Disorder

Treatments for Anxiety Disorders

Antipsychotic Drugs

Filters