Exam 4: Properties of Drugs

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A drug's pKa indicates a drug's pH.

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Feeling physically sick after time passes since taking a chronically used drug would likely be an example of:

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List and describe two approaches for reducing neurotransmission for a receptor.

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Mechanisms for __________________ through the blood-brain barrier consist of channels or other types proteins that transport chemicals through endothelial cell membranes.

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Which of the following approaches might a pharmacologist take in order to increase concentrations of a neurotransmitter in the synaptic cleft?

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A(n)__________________ is a sustained level of drug in the body.

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____________ tolerance can prevent a drug from reaching its site of action.

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A drug metabolite that is unable to cross the blood-brain barrier to its size likely underwent:

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A(n)__________________is a drug that fully activates a neurotransmitter receptor.

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When an agonist binds to a G-protein coupled receptor:

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An increased responsiveness to a drug's effects is called sensitization.

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An active metabolite means that the parent drug is physiological inert.

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