Exam 15: Adaptive, Specific Immunity and Immunization

Describe the major histocompatability complex with regard to its: a) location, b) composition, c) relationship to specific cell markers, and d) role in regulation of immune reactions.

In the secondary response to an antigen, the predominant antibody is

Autoantigens are types of self-antigens that initiate an autoimmune response that can cause damage to host tissue.

A hybridoma results from the fusion of a myeloma cell with a normal _____ cell.

In the primary response to an antigen, the first class of antibody to be secreted is

Cell surface markers involved in immune reactions

Alloantigens are the basis for an individual's blood group and MHC profile.

After secreting antibodies during an immune response, plasma cells then differentiate into memory cells.

Activation of B-cells occurs when antigen bonds to B-cell surface immunoglobulin receptors.

The differences in the classes of immunoglobulins are due primarily to variations in the Fc fragment.

Which kind of T-cell synthesizes perforins and granzymes to destroy viral infected cells, and cancer cells?

The immunoglobulin class that is the only one capable of crossing the placenta is

Immune sera is produced in horses for all the following except

Which part of an antibody molecule contains the variable regions of a heavy and light chain that fold into a groove that will interact directly with and bind to a specific antigen?

Sam works in construction and stepped on a sharp nail.He can't remember the last time he had a tetanus shot.What type of immunity is the most important for him to receive?

Antitoxins

All of the following may be targeted by T_C cells, except

The most significant cells in graft rejection are

Natural killer (NK) cells recognize and identify their targets in an immunologically nonspecific way, but then kill their targets in a manner very similar to that of T_C cells.

Certain body sites contain sequestered molecules, called _____ that escaped assessment during development of immune tolerance and are mistaken as foreign.