Question 1

Matching

-A metabolic reaction resulting in the formation of FADH2 is an example of a(n)___ reaction.

Accepted Answer

A)  anabolic 
B)  adenylate kinase 
C)    
D)  catabolic 
E)  phosphorylase kinase
F) obligate aerobes
G) acyl phosphate
H) proteomics
I) reduction
J) pyrophosphatase
K) autotrophs
L) oxidation
M) ΔG°’ 
A)  anabolic 
B)  adenylate kinase 
C)    
D)  catabolic 
E)  phosphorylase kinase
F) obligate aerobes
G) acyl phosphate
H) proteomics
I) reduction
J) pyrophosphatase
K) autotrophs
L) oxidation
M) ΔG°’ I

Question 2

Matching

-The standard reduction potential under biochemical standard state conditions is symbolized as ______.

Accepted Answer

A)  anabolic 
B)  adenylate kinase 
C)    
D)  catabolic 
E)  phosphorylase kinase
F) obligate aerobes
G) acyl phosphate
H) proteomics
I) reduction
J) pyrophosphatase
K) autotrophs
L) oxidation
M) ΔG°’ 
A)  anabolic 
B)  adenylate kinase 
C)    
D)  catabolic 
E)  phosphorylase kinase
F) obligate aerobes
G) acyl phosphate
H) proteomics
I) reduction
J) pyrophosphatase
K) autotrophs
L) oxidation
M) ΔG°’ C

Question 3

Consider the following metabolic reaction:
Succinyl-CoA + Acetoacetate $\to$Acetoacetyl-CoA + Succinate $\Delta$G°' = -1.25 kJ/mol
The $\Delta$G°' for the hydrolysis of Succinyl-CoA is -33.9 kJ/mol.What is the $\Delta$G°' for the hydrolysis of Acetoacetyl-CoA: Acetoacetyl-CoA $\to$ Acetoacetate + CoA

Accepted Answer

A) -35.2 kJ/mol 
B) -32.7 kJ/mol 
C) +32.7 kJ/mol 
D) +35.2 kJ/mol 
E) none of the above 
A) -35.2 kJ/mol 
B) -32.7 kJ/mol 
C) +32.7 kJ/mol 
D) +35.2 kJ/mol 
E) none of the above B

Question 4

Cells control or regulate the flux through metabolic pathways by means of
(I)allosteric control of enzymes.
(II)covalent modification of enzymes.
(III)genetic control of the concentrations of enzymes.
(IV)genetic expression of allosteric effectors.

Accepted Answer

A) I,II,III,IV 
B) II,III 
C) I,II,IV 
D) I,II,III 
E) I,IV 
A) I,II,III,IV 
B) II,III 
C) I,II,IV 
D) I,II,III 
E) I,IV

Question 5

Which of the following are factors that contribute to the large negative standard free energy change for the reaction shown below?
ATP $\to$ ADP + Pi

Accepted Answer

A) the increase in resonance stabilization in the reactants compare to the products 
B) the precipitation of the insoluble Pi 
C) the addition of a water molecule to the hydrophilic ATP molecule 
D) the decrease in negative charge repulsion in the products compared to reactants 
E) all of the above 
A) the increase in resonance stabilization in the reactants compare to the products 
B) the precipitation of the insoluble Pi 
C) the addition of a water molecule to the hydrophilic ATP molecule 
D) the decrease in negative charge repulsion in the products compared to reactants 
E) all of the above

Question 6

If Z = ATP formed via substrate level phosphorylation in the diagram below,which of the following compounds (represented by an uppercase letter)contains a high-energy bond?

Accepted Answer

A) Compound A 
B) Compound B 
C) Compound C 
D) All have equally high energy. 
E) All have equally low energy. 
A) Compound A 
B) Compound B 
C) Compound C 
D) All have equally high energy. 
E) All have equally low energy.

Question 7

Acyl phosphates such as 1,3-bisphosphoglycerate have a ______ phosphoryl group transfer potential compared to ATP,which can be recognized by the _______ $\Delta$G°' values for hydrolysis.

Accepted Answer

A) greater;more positive 
B) greater;more negative 
C) lower;more positive 
D) lower;more negative 
E) none of the above 
A) greater;more positive 
B) greater;more negative 
C) lower;more positive 
D) lower;more negative 
E) none of the above

Question 8

Use the table below to rank the redox centers in order of increasing ability to produce a favorable electron flow.

Accepted Answer

A) D,Q,F,C,Z 
B) Q,F,C,D,Z 
C) Z,Q,F,C,D 
D) Z,F,C,D,Q 
E) Z,Q,C,Q,D 
A) D,Q,F,C,Z 
B) Q,F,C,D,Z 
C) Z,Q,F,C,D 
D) Z,F,C,D,Q 
E) Z,Q,C,Q,D

Question 9

Organisms that can grow in either the presence or absence of oxygen are classified as

Accepted Answer

A) obligate aerobes 
B) facultative anaerobes 
C) autotrophs 
D) heterotrophs 
E) obligate anaerobes 
A) obligate aerobes 
B) facultative anaerobes 
C) autotrophs 
D) heterotrophs 
E) obligate anaerobes

Question 10

Consider the following metabolic reaction:
3-Phosphoglycerate $\to$2-Phosphoglycerate $\Delta$G°' = +4.40 kJ/mol
What is the $\Delta$G for this reaction when the concentration of 2-phosphoglycerate is 0.290 mM and the concentration of 3-phosphoglycerate is 2.90 mM at 37°C?

Accepted Answer

A) +10.3 kJ/mol 
B) -1.53 kJ/mol 
C) -1.30 kJ/mol 
D) -5.93 kJ/mol 
E) -4.40 kJ/mol 
A) +10.3 kJ/mol 
B) -1.53 kJ/mol 
C) -1.30 kJ/mol 
D) -5.93 kJ/mol 
E) -4.40 kJ/mol

Question 11

NADH is a derivative of

Accepted Answer

A) niacin. 
B) riboflavin. 
C) lipoic acid. 
D) thiamine. 
E) vitamin A. 
A) niacin. 
B) riboflavin. 
C) lipoic acid. 
D) thiamine. 
E) vitamin A.

Question 12

If the diagram below represents a catabolic pathway,and enzyme 1 requires NAD+,what type of reaction does enzyme 1 catalyze?

Accepted Answer

A) reduction 
B) oxidation 
C) isomerization 
D) any of the above
E) none of the above 
A) reduction 
B) oxidation 
C) isomerization 
D) any of the above
E) none of the above

Question 13

Matching

-The reaction NADH $\to$ NAD+ is an example of _____.3

Accepted Answer

A)  anabolic 
B)  adenylate kinase 
C)    
D)  catabolic 
E)  phosphorylase kinase
F) obligate aerobes
G) acyl phosphate
H) proteomics
I) reduction
J) pyrophosphatase
K) autotrophs
L) oxidation
M) ΔG°’ 
A)  anabolic 
B)  adenylate kinase 
C)    
D)  catabolic 
E)  phosphorylase kinase
F) obligate aerobes
G) acyl phosphate
H) proteomics
I) reduction
J) pyrophosphatase
K) autotrophs
L) oxidation
M) ΔG°’

Question 14

Consider the following metabolic reaction:
Succinyl-CoA + Acetoacetate $\to$ Acetoacetyl-CoA + Succinate $\Delta$G°' = -1.25 kJ/mol
What is the Keq for this reaction at 25°C?

Accepted Answer

A) 1)66 
B) 0)602 
C) 1)00 
D) 4)22 x 102 
E) 3)21 
A) 1)66 
B) 0)602 
C) 1)00 
D) 4)22 x 102 
E) 3)21

Question 15

Negative feedback inhibition is one type of _______ metabolic control.

Accepted Answer

A) allosteric 
B) hormonal 
C) covalent modification 
D) genetic 
E) signal transduction 
A) allosteric 
B) hormonal 
C) covalent modification 
D) genetic 
E) signal transduction

Question 16

The vitamin ______ is one of the components of coenzyme A,which is involved in _____.

Accepted Answer

A) pantothenic acid;carboxylation 
B) pantothenic acid;acyl transfer 
C) cobalamin;acyl transfer 
D) riboflavin;carboxylation 
E) niacin;electron transfer 
A) pantothenic acid;carboxylation 
B) pantothenic acid;acyl transfer 
C) cobalamin;acyl transfer 
D) riboflavin;carboxylation 
E) niacin;electron transfer

Question 17

Matching

-The study of the complete set of proteins synthesized in the cell in response to changing conditions is called ______.

Accepted Answer

A)  anabolic 
B)  adenylate kinase 
C)    
D)  catabolic 
E)  phosphorylase kinase
F) obligate aerobes
G) acyl phosphate
H) proteomics
I) reduction
J) pyrophosphatase
K) autotrophs
L) oxidation
M) ΔG°’ 
A)  anabolic 
B)  adenylate kinase 
C)    
D)  catabolic 
E)  phosphorylase kinase
F) obligate aerobes
G) acyl phosphate
H) proteomics
I) reduction
J) pyrophosphatase
K) autotrophs
L) oxidation
M) ΔG°’

Question 18

What type of metabolic control is described in the figure below?

Accepted Answer

A) feed forward activation 
B) product Inhibition 
C) feedback Inhibition 
D) hormonal control 
E) signal transduction control 
A) feed forward activation 
B) product Inhibition 
C) feedback Inhibition 
D) hormonal control 
E) signal transduction control

Question 19

What are the correct coenzyme forms that correspond to X and Y in the following reaction as catalyzed by lactate dehydrogenase?
Pyruvate + X → Lactate + Y

Accepted Answer

A) X = NADH Y = NAD+ 
B) X = NADPH Y = NADP+ 
C) X = NAD+ Y = NADH 
D) X = FAD Y = FADH2 
E) X = NADH Y = NADP+ 
A) X = NADH Y = NAD+ 
B) X = NADPH Y = NADP+ 
C) X = NAD+ Y = NADH 
D) X = FAD Y = FADH2 
E) X = NADH Y = NADP+

Question 20

Consider the following metabolic reaction:
Succinyl-CoA + Acetoacetate $\to$Acetoacetyl-CoA + Succinate $\Delta$G°' = -1.25 kJ/mol
This reaction is

Accepted Answer

A) favorable under standard conditions. 
B) not favorable under standard conditions. 
C) nonspontaneous as written regardless of reactant concentrations 
D) spontaneous as written only when [succinate] and [acetoacetyl-CoA] are high. 
E) favorability of this reaction as written depends on temperature and reactant concentrations 
A) favorable under standard conditions. 
B) not favorable under standard conditions. 
C) nonspontaneous as written regardless of reactant concentrations 
D) spontaneous as written only when [succinate] and [acetoacetyl-CoA] are high. 
E) favorability of this reaction as written depends on temperature and reactant concentrations

Exam 14: Introduction to Metabolism

Matching -A metabolic reaction resulting in the formation of FADH2 is an example of a(n)___ reaction.

Matching -The standard reduction potential under biochemical standard state conditions is symbolized as ______.

Cells control or regulate the flux through metabolic pathways by means of (I)allosteric control of enzymes. (II)covalent modification of enzymes. (III)genetic control of the concentrations of enzymes. (IV)genetic expression of allosteric effectors.

Which of the following are factors that contribute to the large negative standard free energy change for the reaction shown below? ATP →\to→ ADP + Pi

If Z = ATP formed via substrate level phosphorylation in the diagram below,which of the following compounds (represented by an uppercase letter)contains a high-energy bond?

Acyl phosphates such as 1,3-bisphosphoglycerate have a ______ phosphoryl group transfer potential compared to ATP,which can be recognized by the _______ Δ\DeltaΔ G°' values for hydrolysis.

Use the table below to rank the redox centers in order of increasing ability to produce a favorable electron flow.

Organisms that can grow in either the presence or absence of oxygen are classified as

Consider the following metabolic reaction: 3-Phosphoglycerate →\to→ 2-Phosphoglycerate Δ\DeltaΔ G°' = +4.40 kJ/mol What is the Δ\DeltaΔ G for this reaction when the concentration of 2-phosphoglycerate is 0.290 mM and the concentration of 3-phosphoglycerate is 2.90 mM at 37°C?

NADH is a derivative of

If the diagram below represents a catabolic pathway,and enzyme 1 requires NAD+,what type of reaction does enzyme 1 catalyze?

Matching -The reaction NADH →\to→ NAD+ is an example of _____.3

Consider the following metabolic reaction: Succinyl-CoA + Acetoacetate →\to→ Acetoacetyl-CoA + Succinate Δ\DeltaΔ G°' = -1.25 kJ/mol What is the Keq for this reaction at 25°C?

Negative feedback inhibition is one type of _______ metabolic control.

The vitamin ______ is one of the components of coenzyme A,which is involved in _____.

Matching -The study of the complete set of proteins synthesized in the cell in response to changing conditions is called ______.

What type of metabolic control is described in the figure below?

What are the correct coenzyme forms that correspond to X and Y in the following reaction as catalyzed by lactate dehydrogenase? Pyruvate + X → Lactate + Y

Consider the following metabolic reaction: Succinyl-CoA + Acetoacetate →\to→ Acetoacetyl-CoA + Succinate Δ\DeltaΔ G°' = -1.25 kJ/mol This reaction is

Introduction to the Chemistry of Life

Water

Nucleotides, nucleic Acids, and Genetic Information

Amino Acids

Proteins: Primary Structure

Proteins: Three-Dimensional Structure

Protein Function Part I: Myoglobin and Hemoglobin

Carbohydrates

Lipids and Biological Membranes

Membrane Transport

Enzyme Catalysis

Enzyme Kinetics, inhibition and Control

Biochemical Signaling

Glucose Catabolism

Glycogen Metabolism and Gluconeogenesis

Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Photosynthesis

Lipid Metabolism

Amino Acid Metabolism

Mammalian Fuel Metabolism: Integration and Regulation

Nucleotide Metabolism

Nucleic Acid Structure

DNA Replication, repair and Recombination

Transcription and Rna Processing

Protein Synthesis

Regulation of Gene Expression

Filters

Matching -A metabolic reaction resulting in the formation of FADH₂ is an example of a(n)___ reaction.

Which of the following are factors that contribute to the large negative standard free energy change for the reaction shown below? ATP $\to$ ADP + P_i

Acyl phosphates such as 1,3-bisphosphoglycerate have a phosphoryl group transfer potential compared to ATP,which can be recognized by the _ $\Delta$ G°' values for hydrolysis.

Consider the following metabolic reaction: 3-Phosphoglycerate $\to$ 2-Phosphoglycerate $\Delta$ G°' = +4.40 kJ/mol What is the $\Delta$ G for this reaction when the concentration of 2-phosphoglycerate is 0.290 mM and the concentration of 3-phosphoglycerate is 2.90 mM at 37°C?

If the diagram below represents a catabolic pathway,and enzyme 1 requires NAD⁺,what type of reaction does enzyme 1 catalyze?

Matching -The reaction NADH $\to$ NAD⁺ is an example of _____.3

Consider the following metabolic reaction: Succinyl-CoA + Acetoacetate $\to$ Acetoacetyl-CoA + Succinate $\Delta$ G°' = -1.25 kJ/mol What is the K_eq for this reaction at 25°C?

The vitamin __ is one of the components of coenzyme A,which is involved in _.

Consider the following metabolic reaction: Succinyl-CoA + Acetoacetate $\to$ Acetoacetyl-CoA + Succinate $\Delta$ G°' = -1.25 kJ/mol This reaction is