Exam 14: Introduction to Metabolism

Which of the following increase the phosphate transfer potential of compound? (I)electrostatic repulsion between charged groups on the reactant (II)resonance stabilization of the hydrolysis products (III)greater energy of solvation of the hydrolysis products (IV)the presence of a enol group in the reactants

Consider the following metabolic reaction: 2-Phosphoglycerate $\to$ 3-Phosphoglycerate $\Delta$ G°' = −4.40 kJ/mol What can be said about this reaction when the concentration of 2-phosphoglycerate is 0.490 mM and the concentration of 3-phosphoglycerate is 2.90 mM at 25°C? (I)This reaction is endergonic under these conditions. (II)This reaction is exergonic under these conditions. (III)This reaction is at equilibrium under these conditions. (IV)This reaction is not favorable under standard conditions.

Matching -Prokaryotes that are able to synthesize all of their cellular components from simple molecules such as CO₂,H₂O,NH₃,and H₂S are called ______.

Acetyl-CoA contains a ____ bond which often provides the energy required for substrate-level phosphorylation.

Matching -1,3-Bisphosphoglycerate is an example of a(n)______.

In eukaryotes,glycolysis typically occurs in the

The K_eq is 0.503 at 25°C for the following reaction.What is the $\Delta$ G°' for this reaction? D-Glucose-6-phosphate $\to$ D-Fructose-6-phosphate $\Delta$ G°'= ?

Consider the following metabolic reaction important in muscle and nerve cells: ATP + creatine $\leftrightarrows$ phosphocreatine + ADP $\Delta$ G°' = +12.6 kJ/mol Under intracellular conditions,the $\Delta$ G for the reaction,which is catalyzed by the enzyme creatine kinase,is ~0 kJ/mol.From this information we can conclude that

______ is the most reliable systems biology approach to assess gene expression.

Which of the following is (are)true regarding vitamins? (I)They are essential organic molecules an organism is unable to synthesize. (II)Some water soluble vitamins mediate electron-transfer reactions. (III)In humans,the water soluble vitamins converted into organic coenzymes. IV)In humans,the fat soluble vitamins mediate group transfer reactions.

Compound "K" is the ultimate product of a linear metabolic pathway consisting of ten enzymatically catalyzed reactions as shown below. 1 2 3 4 5 6 7 8 9 10 A $\to$ B $\to$ C $\to$ D $\to$ E $\to$ F $\to$ G $\to$ H $\to$ I $\to$ J $\to$ K Complete the following description. If "K" inhibits activity of enzyme "5",then enzyme "5" is under ___ control.If enzyme "3" becomes activated in response to activity of protein kinase A only when compound "A" is present,then enzyme "3" is under ___ control.If enzyme "2" is only expressed in the presence of high concentrations of "A," then enzyme "2" is under ___ control.If all of these are true,high concentrations of "__" will decrease the flux through the pathway.

The enzyme inorganic pyrophosphatase catalyzes the hydrolysis of bonds in ___.