Question 1

Which atoms,or groups attached to them,face into the minor groove of B-DNA?

Accepted Answer

A) purine 1 & 2;pyrimidine 2 & 3 
B) purine 2 & 3;pyrimidine 2 
C) purine 8 & 9;pyrimidine 1 & 6 
D) purine 6 & 7;pyrimidine 4 & 5 
E) purine 6 & 7;pyrimidine 2 
A) purine 1 & 2;pyrimidine 2 & 3 
B) purine 2 & 3;pyrimidine 2 
C) purine 8 & 9;pyrimidine 1 & 6 
D) purine 6 & 7;pyrimidine 4 & 5 
E) purine 6 & 7;pyrimidine 2

Question 2

Which of the following prokaryotic enzymes can introduce negative supercoils?

Accepted Answer

A) topoismerase IA 
B) topoismerase III 
C) DNA gyrase 
D) all of the above 
E) none of the above 
A) topoismerase IA 
B) topoismerase III 
C) DNA gyrase 
D) all of the above 
E) none of the above

Question 3

Indirect readout refers to
(I)a protein's ability to form hydrogen bonds through a network of water molecules.
(II)the 5' to 3' sequence on the opposite strand of a DNA helix.
(III)a protein's ability to recognize a specific DNA sequence by its backbone conformation and flexibility.
(IV)the protein's ability to make hydrogen bonds with nonesterified phosphate oxygens

Accepted Answer

A) I,III,IV 
B) II,IV 
C) III,IV 
D) I,III 
E) I,IV 
A) I,III,IV 
B) II,IV 
C) III,IV 
D) I,III 
E) I,IV

Question 4

Matching
Choose the correct answer from the list.Not all the answers will be used.

-________,an ion that intercalates into double-stranded DNA,is often used for staining gels.

Accepted Answer

A)  type I 
B)  ribocatalyzers 
C)  C2´-endo 
D)  repressors 
E)  ethidium
F) type II
G) C3´-endo 
H) hybridized
I) interchanged
J) supercoiled
K) cooperative
L) non-cooperative
M) underwound
N) ribozymes
O) deuterium
P) zinc finger
Q) leucine zipper 
A)  type I 
B)  ribocatalyzers 
C)  C2´-endo 
D)  repressors 
E)  ethidium
F) type II
G) C3´-endo 
H) hybridized
I) interchanged
J) supercoiled
K) cooperative
L) non-cooperative
M) underwound
N) ribozymes
O) deuterium
P) zinc finger
Q) leucine zipper

Question 5

Which of the following materials would be useful for a researcher seeking to purify chromosomal DNA of lysed E.coli cells from cellular proteins and RNA?

Accepted Answer

A) ethidium bromide 
B) hydroxyapatite 
C) acridine orange 
D) proflavin 
E) DNA gyrase 
A) ethidium bromide 
B) hydroxyapatite 
C) acridine orange 
D) proflavin 
E) DNA gyrase

Question 6

Which of the following best describes the structure of a nucleosome?

Accepted Answer

A) approximately 150 bp of DNA wrapped around a set of two H2A/H2B and two H3/H4 dimers with H1 on the outside 
B) approximately 15 bp of DNA wrapped around an octamer of H1 with H2A,B,H3 and H4 on the outside 
C) approximately 150 bp of DNA wrapped around a tetramer of either H2A/H2B or H3/H4 with H1 on the outside 
D) approximately 1500 bp of DNA wrapped around a tetramer of either H2A/H2B or H3/H4 with H1 on the outside 
E) approximately 200 bp of DNA wrapped around a tetramer of H2A,H2B,H3,and H4 with H1 on the outside 
A) approximately 150 bp of DNA wrapped around a set of two H2A/H2B and two H3/H4 dimers with H1 on the outside 
B) approximately 15 bp of DNA wrapped around an octamer of H1 with H2A,B,H3 and H4 on the outside 
C) approximately 150 bp of DNA wrapped around a tetramer of either H2A/H2B or H3/H4 with H1 on the outside 
D) approximately 1500 bp of DNA wrapped around a tetramer of either H2A/H2B or H3/H4 with H1 on the outside 
E) approximately 200 bp of DNA wrapped around a tetramer of H2A,H2B,H3,and H4 with H1 on the outside

Question 7

Matching
Choose the correct answer from the list.Not all the answers will be used.

-Naturally occurring circular DNA is typically _______.

Accepted Answer

A)  type I 
B)  ribocatalyzers 
C)  C2´-endo 
D)  repressors 
E)  ethidium
F) type II
G) C3´-endo 
H) hybridized
I) interchanged
J) supercoiled
K) cooperative
L) non-cooperative
M) underwound
N) ribozymes
O) deuterium
P) zinc finger
Q) leucine zipper 
A)  type I 
B)  ribocatalyzers 
C)  C2´-endo 
D)  repressors 
E)  ethidium
F) type II
G) C3´-endo 
H) hybridized
I) interchanged
J) supercoiled
K) cooperative
L) non-cooperative
M) underwound
N) ribozymes
O) deuterium
P) zinc finger
Q) leucine zipper

Question 8

The chromosomes of some viruses and bacteria are ______ and often ______.

Accepted Answer

A) linear;single stranded 
B) linear;supercoiled 
C) circular;single stranded 
D) circular;supercoiled 
E) none of the above 
A) linear;single stranded 
B) linear;supercoiled 
C) circular;single stranded 
D) circular;supercoiled 
E) none of the above

Question 9

Matching
Choose the correct answer from the list.Not all the answers will be used.

-In prokaryotes,many of the _____ that bind to DNA contain a HTH motif.

Accepted Answer

A)  type I 
B)  ribocatalyzers 
C)  C2´-endo 
D)  repressors 
E)  ethidium
F) type II
G) C3´-endo 
H) hybridized
I) interchanged
J) supercoiled
K) cooperative
L) non-cooperative
M) underwound
N) ribozymes
O) deuterium
P) zinc finger
Q) leucine zipper 
A)  type I 
B)  ribocatalyzers 
C)  C2´-endo 
D)  repressors 
E)  ethidium
F) type II
G) C3´-endo 
H) hybridized
I) interchanged
J) supercoiled
K) cooperative
L) non-cooperative
M) underwound
N) ribozymes
O) deuterium
P) zinc finger
Q) leucine zipper

Question 10

Matching
Choose the correct answer from the list.Not all the answers will be used.

-The denaturation of DNA is a ______ cooperative process.

Accepted Answer

A)  type I 
B)  ribocatalyzers 
C)  C2´-endo 
D)  repressors 
E)  ethidium
F) type II
G) C3´-endo 
H) hybridized
I) interchanged
J) supercoiled
K) cooperative
L) non-cooperative
M) underwound
N) ribozymes
O) deuterium
P) zinc finger
Q) leucine zipper 
A)  type I 
B)  ribocatalyzers 
C)  C2´-endo 
D)  repressors 
E)  ethidium
F) type II
G) C3´-endo 
H) hybridized
I) interchanged
J) supercoiled
K) cooperative
L) non-cooperative
M) underwound
N) ribozymes
O) deuterium
P) zinc finger
Q) leucine zipper

Which atoms,or groups attached to them,face into the minor groove of B-DNA?

Which of the following prokaryotic enzymes can introduce negative supercoils?

Matching Choose the correct answer from the list.Not all the answers will be used. -________,an ion that intercalates into double-stranded DNA,is often used for staining gels.

Which of the following materials would be useful for a researcher seeking to purify chromosomal DNA of lysed E.coli cells from cellular proteins and RNA?

Which of the following best describes the structure of a nucleosome?

Matching Choose the correct answer from the list.Not all the answers will be used. -Naturally occurring circular DNA is typically _______.

The chromosomes of some viruses and bacteria are and often .

Matching Choose the correct answer from the list.Not all the answers will be used. -In prokaryotes,many of the _____ that bind to DNA contain a HTH motif.

Matching Choose the correct answer from the list.Not all the answers will be used. -The denaturation of DNA is a ______ cooperative process.

Introduction to the Chemistry of Life

Water

Nucleotides, nucleic Acids, and Genetic Information

Amino Acids

Proteins: Primary Structure

Proteins: Three-Dimensional Structure

Protein Function Part I: Myoglobin and Hemoglobin

Carbohydrates

Lipids and Biological Membranes

Membrane Transport

Enzyme Catalysis

Enzyme Kinetics, inhibition and Control

Biochemical Signaling

Introduction to Metabolism

Glucose Catabolism

Glycogen Metabolism and Gluconeogenesis

Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Photosynthesis

Lipid Metabolism

Amino Acid Metabolism

Mammalian Fuel Metabolism: Integration and Regulation

Nucleotide Metabolism

DNA Replication, repair and Recombination

Transcription and Rna Processing

Protein Synthesis

Regulation of Gene Expression

Filters

Exam 24: Nucleic Acid Structure

Which atoms,or groups attached to them,face into the minor groove of B-DNA?

Which of the following prokaryotic enzymes can introduce negative supercoils?

Matching Choose the correct answer from the list.Not all the answers will be used. -________,an ion that intercalates into double-stranded DNA,is often used for staining gels.

Which of the following materials would be useful for a researcher seeking to purify chromosomal DNA of lysed E.coli cells from cellular proteins and RNA?

Which of the following best describes the structure of a nucleosome?

Matching Choose the correct answer from the list.Not all the answers will be used. -Naturally occurring circular DNA is typically _______.

The chromosomes of some viruses and bacteria are ______ and often ______.

Matching Choose the correct answer from the list.Not all the answers will be used. -In prokaryotes,many of the _____ that bind to DNA contain a HTH motif.

Matching Choose the correct answer from the list.Not all the answers will be used. -The denaturation of DNA is a ______ cooperative process.

Introduction to the Chemistry of Life

Water

Nucleotides, nucleic Acids, and Genetic Information

Amino Acids

Proteins: Primary Structure

Proteins: Three-Dimensional Structure

Protein Function Part I: Myoglobin and Hemoglobin

Carbohydrates

Lipids and Biological Membranes

Membrane Transport

Enzyme Catalysis

Enzyme Kinetics, inhibition and Control

Biochemical Signaling

Introduction to Metabolism

Glucose Catabolism

Glycogen Metabolism and Gluconeogenesis

Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Photosynthesis

Lipid Metabolism

Amino Acid Metabolism

Mammalian Fuel Metabolism: Integration and Regulation

Nucleotide Metabolism

DNA Replication, repair and Recombination

Transcription and Rna Processing

Protein Synthesis

Regulation of Gene Expression

Filters

The chromosomes of some viruses and bacteria are and often .