Exam 27: Interaction of the Fibrinolytic, Coagulation, and Kinin Systems; Disseminated Intravascular Coagulation; and Related Pathology

The molecular components of the fibrinolytic system consist of all of the following except:

Thrombin-anti-thrombin complexes are elevated in which of the following conditions?

Which serine protease proteolytically degrades both fibrin in clots and native fibrinogen in the circulation into a series of well-characterized end-products collectively known as fibrin/fibrinogen degradation products?

DIC associated with conditions activated by factor X include which of the following?

Diffuse hemorrhage present in DIC is the result of:

Native plasminogen is a single-chain plasma __________ of approximately 90,000 daltons that circulates in two molecular forms.

Which laboratory tests are abnormal in DIC?

Blood component replacement therapy in DIC includes transfusion of:

Which laboratory test differentiates compensated DIC from a state of hypercoagulability DIC?

What red cell morphology might you expect in DIC?

Which of the following is/are consistent with a compensated state of DIC?

__________ activators are serine proteases present in the blood and a variety of other tissues, particularly the vascular endothelium.

All of the following are known mechanisms for activation of the coagulation cascade except:

The secondary action of the fibrinolytic system in DIC involves the action of __________ on fibrin/fibrinogen.

Which of the following are characteristics of urokinase?

Streptokinase forms a 1:1 stoichiometric complex with __________.

Thrombotic thrombocytopenic purpura (TTP) represents an abnormality of the fibrinolytic system in which there is diminished __________ activity in plasma and blood vessels affected with microthrombi.

Heparin therapy is most effective in the __________ state of DIC with evident vascular thrombosis.

What is the overall effect of ₂-anti-plasmin inhibitor?

The clinical picture in DIC is dependent on: