Question 1

Which of the following is not true of eukaryotic DNA replication?

Accepted Answer

A)  It is semiconservative. 
B)  It is discontinuous. 
C)  It proceeds 3' to 5' on the lagging strand. 
D)  It proceeds 5' to 3' on the leading strand. 
E)  It requires DNA polymerase activity. 
A)  It is semiconservative. 
B)  It is discontinuous. 
C)  It proceeds 3' to 5' on the lagging strand. 
D)  It proceeds 5' to 3' on the leading strand. 
E)  It requires DNA polymerase activity.

Question 2

DNA polymerase catalyzes elongation of DNA chains

Accepted Answer

A)  in the 5' to direction through the addition of a deoxyribonucleotide complementary to the primer. 
B)  in the to 5' direction through the addition of a deoxyribonucleotide to the OH of the primer strand. 
C)  in the 5' to direction through the addition of a ribonucleotide to the OH of the primer strand selecting a purine or pyrimidine base complementary to the template strand. 
D)  in the to 5' direction through the addition of a deoxyribonucleotide to the OH of the primer strand selecting a purine or pyrimidine base complementary to the template strand. 
E)  in the 5' to direction through the addition of a deoxyribonucleotide to the OH of the primer strand selecting a purine or pyrimidine base complementary to the template strand. 
A)  in the 5' to direction through the addition of a deoxyribonucleotide complementary to the primer. 
B)  in the to 5' direction through the addition of a deoxyribonucleotide to the OH of the primer strand. 
C)  in the 5' to direction through the addition of a ribonucleotide to the OH of the primer strand selecting a purine or pyrimidine base complementary to the template strand. 
D)  in the to 5' direction through the addition of a deoxyribonucleotide to the OH of the primer strand selecting a purine or pyrimidine base complementary to the template strand. 
E)  in the 5' to direction through the addition of a deoxyribonucleotide to the OH of the primer strand selecting a purine or pyrimidine base complementary to the template strand.

Question 3

The polynucleotide ligase reaction involves

Accepted Answer

A)  activation of the end of a DNA strand. 
B)  the formation of a cyclical 2',nucleoside phosphate. 
C)  the intermediate formation of an anhydride linkage be- tween AMP and the 5'-phosphate of a DNA strand. 
D)  the intermediate formation of an ester bond between AMP and DNA. 
E)  the cleavage of GTP. 
A)  activation of the end of a DNA strand. 
B)  the formation of a cyclical 2',nucleoside phosphate. 
C)  the intermediate formation of an anhydride linkage be- tween AMP and the 5'-phosphate of a DNA strand. 
D)  the intermediate formation of an ester bond between AMP and DNA. 
E)  the cleavage of GTP.

Question 4

When cytosine deaminates in DNA a uracil residue results. All of the following enzymes are involved in the repair of this uracil EXCEPT

Accepted Answer

A)  DNA ligase 
B)  AP endonuclease 
C)  uracil-DNA glycosylase 
D)  photoreactivating enzyme (DNA photolyase) 
E)  DNA polymerase 
A)  DNA ligase 
B)  AP endonuclease 
C)  uracil-DNA glycosylase 
D)  photoreactivating enzyme (DNA photolyase) 
E)  DNA polymerase

Question 5

The ---> 5' exonuclease activity of DNA polymerase I

Accepted Answer

A)  provides primers with free hydroxyl groups for chain extension. 
B)  is similar to the mode of action of an RNA polymerase. 
C)  helps remove RNA primers during replication. 
D)  provides an error-correcting mechanism during replication and repair synthesis. 
E)  prevents bidirectional replication of the genome. 
A)  provides primers with free hydroxyl groups for chain extension. 
B)  is similar to the mode of action of an RNA polymerase. 
C)  helps remove RNA primers during replication. 
D)  provides an error-correcting mechanism during replication and repair synthesis. 
E)  prevents bidirectional replication of the genome.

Question 6

DNA synthesis is called:

Accepted Answer

A)  replication 
B)  transcription 
C)  translation 
D)  transformation 
E)  polymerization 
A)  replication 
B)  transcription 
C)  translation 
D)  transformation 
E)  polymerization

Question 7

Okazaki fragments

Accepted Answer

A)  are found on the leading strand of newly synthesized DNA 
B)  are the short regions of RNA added by the primosome 
C)  do not contain RNA 
D)  is another name for restriction fragments 
E)  prime DNA Pol I directed DNA synthesis 
A)  are found on the leading strand of newly synthesized DNA 
B)  are the short regions of RNA added by the primosome 
C)  do not contain RNA 
D)  is another name for restriction fragments 
E)  prime DNA Pol I directed DNA synthesis

Which of the following is not true of eukaryotic DNA replication?

DNA polymerase catalyzes elongation of DNA chains

The polynucleotide ligase reaction involves

When cytosine deaminates in DNA a uracil residue results. All of the following enzymes are involved in the repair of this uracil EXCEPT

The ---> 5' exonuclease activity of DNA polymerase I

DNA synthesis is called:

Okazaki fragments

Eukaryotic Cell Structure

DNA and RNA: Composition and Structure

Protein I: Composition and Structure

RNA: Transcription and Rna Processing

Protein Synthesis: Translation and Posttranslational Modifications

Recombinant Dna and Biotechnology

Regulation of Gene Expression

Protein II: Structure-Function Relationships in Protein Families

Enzymes: Classification, Kinetics, and Control

The Cytochromes P450 and Nitric Oxide Synthases

Biological Membranes: Structure and Membrane Transport

Fundamentals of Signal Transduction

Bioenergetics and Oxidative Metabolism

Carbohydrate Metabolism I: Major Metabolic Pathways and Their Control

Carbohydrate Metabolism II: Special Pathways and Glycoconjugates

Lipid Metabolism I: Synthesis, Storage, and Utilization of Fatty Acids and Triacylglycerols

Lipid Metabolism II: Pathways of Metabolism of Special Lipids

Amino Acid Metabolism

Purine and Pyrimidine Nucleotide Metabolism

Metabolic Interrelationships

Biochemistry of Hormones

Molecular Cell Biology

Cell Cycle, Programmed Cell Death, and Cancer

Digestion and Absorption of Basic Nutritional Constituents

Digestion and Absorption of Basic Nutritional Constituents

Principles of Nutrition I and II

Filters

Exam 4: DNA Replication, Recombination, and Repair

Which of the following is not true of eukaryotic DNA replication?

DNA polymerase catalyzes elongation of DNA chains

The polynucleotide ligase reaction involves

When cytosine deaminates in DNA a uracil residue results. All of the following enzymes are involved in the repair of this uracil EXCEPT

The ---> 5' exonuclease activity of DNA polymerase I

DNA synthesis is called:

Okazaki fragments

Eukaryotic Cell Structure

DNA and RNA: Composition and Structure

Protein I: Composition and Structure

RNA: Transcription and Rna Processing

Protein Synthesis: Translation and Posttranslational Modifications

Recombinant Dna and Biotechnology

Regulation of Gene Expression

Protein II: Structure-Function Relationships in Protein Families

Enzymes: Classification, Kinetics, and Control

The Cytochromes P450 and Nitric Oxide Synthases

Biological Membranes: Structure and Membrane Transport

Fundamentals of Signal Transduction

Bioenergetics and Oxidative Metabolism

Carbohydrate Metabolism I: Major Metabolic Pathways and Their Control

Carbohydrate Metabolism II: Special Pathways and Glycoconjugates

Lipid Metabolism I: Synthesis, Storage, and Utilization of Fatty Acids and Triacylglycerols

Lipid Metabolism II: Pathways of Metabolism of Special Lipids

Amino Acid Metabolism

Purine and Pyrimidine Nucleotide Metabolism

Metabolic Interrelationships

Biochemistry of Hormones

Molecular Cell Biology

Cell Cycle, Programmed Cell Death, and Cancer

Digestion and Absorption of Basic Nutritional Constituents

Digestion and Absorption of Basic Nutritional Constituents

Principles of Nutrition I and II

Filters