Question 1

Provide the structure(s) of the major intermediate product(s) in the following reaction sequence.

Accepted Answer

The answer of Provide the structure(s) of the major intermediate...

Question 2

Which of the following criteria is necessary for a nucleophilic aromatic substitution reaction?

Accepted Answer

A)  the ring must conatin a very strong electron withdrawing group 
B)  the ring must contain a leaving group 
C)  the leaving droup must be ortho or para to the electron withdrawing group 
D)  the leaving droup must be meta to the electron withdrawing group 
E)  A, B & C 
A)  the ring must conatin a very strong electron withdrawing group 
B)  the ring must contain a leaving group 
C)  the leaving droup must be ortho or para to the electron withdrawing group 
D)  the leaving droup must be meta to the electron withdrawing group 
E)  A, B & C

Question 3

Predict the structure of the product for the following reaction.

Accepted Answer

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Question 4

Predict the product(s) for the following reaction.

Accepted Answer

The answer of Predict the product(s) for the following reaction....

Question 5

Predict the major product for the following reaction.

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  V 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  V

Question 6

Which one of the following compounds would be least reactive toward electrophilic aromatic substitution?

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  V 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  V

Question 7

Provide the reagents necessary to carry out the following conversion.

Accepted Answer

1. HNO₃/H₂SO

Question 8

Predict the structure of the major product for the following reaction.

Accepted Answer

The answer of Predict the structure of the major product...

Question 9

Predict the major product for the following reaction and provide a stepwise curved arrow mechanism for the formation of the product.

Accepted Answer

The answer of Predict the major product for the following...

Question 10

Which of the following reagents would you use as the basis for a simple chemical test that would distinguish between ethylbenzene and styrene?

Accepted Answer

A)  NaI/acetone 
B)  Br2/CCl4 
C)  NaOH/H2O 
D)  NaBH4/CH3OH 
E)  HCl/H2O 
A)  NaI/acetone 
B)  Br2/CCl4 
C)  NaOH/H2O 
D)  NaBH4/CH3OH 
E)  HCl/H2O

Question 11

Provide the reagents necessary to carry out the following conversion.

Accepted Answer

1. Cl₂/FeCl

Question 12

Arrange the following compounds in order of decreasing reactivity towards electrophilic aromatic substitution:

Accepted Answer

A)  V>II>I>III>IV 
B)  II>V>III>I>IV 
C)  IV>I>III>V>II 
D)  III>II>I>IV>V 
E)  IV>V>II>I>III 
A)  V>II>I>III>IV 
B)  II>V>III>I>IV 
C)  IV>I>III>V>II 
D)  III>II>I>IV>V 
E)  IV>V>II>I>III

Question 13

Predict the major product for the following reaction.

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  no reaction 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  no reaction

Question 14

Provide the reagents necessary to carry out the following conversion.

Accepted Answer

1. fuming

Question 15

Predict the structure of the major product for the following reaction.

Accepted Answer

The answer of Predict the structure of the major product...

Question 16

Which one of the following substituents will direct the incoming group to the meta position during electrophilic aromatic substitution?

Accepted Answer

A)  -NO2 
B)  -C$ \equiv$N 
C)  -CCl3 
D)  -COOH 
E)  all of these 
A)  -NO2 
B)  -C$ \equiv$N 
C)  -CCl3 
D)  -COOH 
E)  all of these

Question 17

Predict the product for the following reaction.

Accepted Answer

The answer of Predict the product for the following reaction....

Question 18

Predict the product for the following reaction.

Accepted Answer

The answer of Predict the product for the following reaction....

Question 19

Predict the major product for the following reaction.

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  V 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  V

Question 20

Provide the structure(s) of the intermediate product(s) in the following reaction sequence

Accepted Answer

The answer of Provide the structure(s) of the intermediate product(s)...

Exam 19: Aromatic Substitution Reactions

Provide the structure(s) of the major intermediate product(s) in the following reaction sequence.

Which of the following criteria is necessary for a nucleophilic aromatic substitution reaction?

Predict the structure of the product for the following reaction.

Predict the product(s) for the following reaction.

Predict the major product for the following reaction.

Which one of the following compounds would be least reactive toward electrophilic aromatic substitution?

Provide the reagents necessary to carry out the following conversion.

Predict the structure of the major product for the following reaction.

Predict the major product for the following reaction and provide a stepwise curved arrow mechanism for the formation of the product.

Which of the following reagents would you use as the basis for a simple chemical test that would distinguish between ethylbenzene and styrene?

Provide the reagents necessary to carry out the following conversion.

Arrange the following compounds in order of decreasing reactivity towards electrophilic aromatic substitution:

Predict the major product for the following reaction.

Provide the reagents necessary to carry out the following conversion.

Predict the structure of the major product for the following reaction.

Which one of the following substituents will direct the incoming group to the meta position during electrophilic aromatic substitution?

Predict the product for the following reaction.

Predict the product for the following reaction.

Predict the major product for the following reaction.

Provide the structure(s) of the intermediate product(s) in the following reaction sequence

A Review of General Chemistry: Electrons, Bonds, and Molecular Properties

Molecular Representations

Acids and Bases

Alkanes and Cycloalkanes

Stereoisomerism

Chemical Reactivity and Mechanisms

Substitution Reactions

Alkenes: Structure and Preparation Via Elimination Reactions

Addition Reactions of Alkenes

Alkynes

Radical Reactions

Synthesis

Alcohols and Phenols

Ethers and Epoxides; Thiols and Sulfides

Infrared Spectroscopy and Mass Spectrometry

Nuclear Magnetic Resonance Spectroscopy

Conjugated Pi Systems and Pericyclic Reactions

Aromatic Compounds

Aldehydes and Ketones

Carboxylic Acids and Their Derivatives

Alpha Carbon Chemistry: Enols and Enolates

Amines

Carbohydrates

Amino Acids, Peptides, and Proteins

Lipids

Synthetic Polymers

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