Question 1

Draw a reaction diagram for the following SN1 reaction.

Accepted Answer

Question 2

Draw the anticipated major product for the following reaction.

Accepted Answer

The answer of Draw the anticipated major product for the...

Question 3

Is the following nucleophile strong or weak? CN-

Accepted Answer

A) Strong 
B) Weak 
C) Not a nucleophile 
A) Strong 
B) Weak 
C) Not a nucleophile

Question 4

Which of the following is a reasonable definition of a concerted reaction?

Accepted Answer

A) It is a reaction which takes place in a series of steps. 
B) It is a reaction which produces a loud noise. 
C) It is a reaction in which all bond-breaking and bond-forming occurs at the same time. 
D) It is a substitution reaction. 
A) It is a reaction which takes place in a series of steps. 
B) It is a reaction which produces a loud noise. 
C) It is a reaction in which all bond-breaking and bond-forming occurs at the same time. 
D) It is a substitution reaction.

Question 5

What is the mechanism for the following reaction?

Accepted Answer

The answer of What is the mechanism for the following...

Question 6

For the following reaction,draw the product.

Accepted Answer

The answer of For the following reaction,draw the product. ...

Question 7

How would you accomplish the following transformation?

Accepted Answer

The answer of How would you accomplish the following transformation?...

Question 8

Is the following nucleophile strong or weak? H2S

Accepted Answer

A) Strong 
B) Weak 
C) Not a nucleophile 
A) Strong 
B) Weak 
C) Not a nucleophile

Question 9

Given the following rate law,what will happen to the rate if the concentration of MeI is doubled and the concentration of Me3N is halved? Rate = k[Me3N][MeI]

Accepted Answer

A) It will be doubled. 
B) It will not change. 
C) It will decrease in half. 
D) It will increase very slightly. 
A) It will be doubled. 
B) It will not change. 
C) It will decrease in half. 
D) It will increase very slightly.

Question 10

Provide an example of a strong nucleophile.

Accepted Answer

There are

Question 11

Which reagents would you use for the following reaction?

Accepted Answer

A) HBr in water 
B) NaBr in water 
C) Ethyl bromide 
D) Ethyl iodide 
A) HBr in water 
B) NaBr in water 
C) Ethyl bromide 
D) Ethyl iodide

Question 12

Is the following nucleophile strong or weak? HO-

Accepted Answer

A) Strong 
B) Weak 
C) Not a nucleophile 
A) Strong 
B) Weak 
C) Not a nucleophile

Question 13

Rank the following substrates from most to least reactive in an SN1 reaction.

Accepted Answer

A) A>B>C>D 
B) A>B>D>C 
C) D>A>B>C 
D) D>C>B>A 
A) A>B>C>D 
B) A>B>D>C 
C) D>A>B>C 
D) D>C>B>A

Question 14

What set of reaction conditions should favor an SN2 reaction on 2-bromo-3-methylbutane?

Accepted Answer

A) weak nucleophile in a protic solvent 
B) weak nucleophile in an aprotic solvent 
C) strong nucleophile in a protic solvent 
D) strong nucleophile in an aprotic solvent 
A) weak nucleophile in a protic solvent 
B) weak nucleophile in an aprotic solvent 
C) strong nucleophile in a protic solvent 
D) strong nucleophile in an aprotic solvent

Question 15

Rank the following substrates from most to least reactive in an SN2 reaction.

Accepted Answer

A) A>B>C>D 
B) D>C>B>A 
C) C>B>A>D 
D) D>C>B>A. 
A) A>B>C>D 
B) D>C>B>A 
C) C>B>A>D 
D) D>C>B>A.

Question 16

What is the product of the following reaction.Include stereochemistry.

Accepted Answer

The answer of What is the product of the following...

Question 17

Rank the following substrates from most to least reactive in an SN2 reaction.

Accepted Answer

A) A>B>C>D 
B) D>C>B>A 
C) A>C>B>D 
D) .D>C>B>A 
A) A>B>C>D 
B) D>C>B>A 
C) A>C>B>D 
D) .D>C>B>A

Question 18

From the given starting material,how could you stereospecifically form the given product?

Accepted Answer

The answer of From the given starting material,how could you...

Question 19

What reaction mechanism is most likely for substitution on the following compound?

Accepted Answer

A) SN1 
B) SN2 
C) Either 
D) Neither 
A) SN1 
B) SN2 
C) Either 
D) Neither

Question 20

Which reagents would you use for the following reaction?

Accepted Answer

A) H2S in water 
B) H2S in DMSO 
C) NaSH in water 
D) NaSH in DMSO 
A) H2S in water 
B) H2S in DMSO 
C) NaSH in water 
D) NaSH in DMSO

Exam 7: Substitution Reactions

Draw a reaction diagram for the following SN1 reaction.

Draw the anticipated major product for the following reaction.

Is the following nucleophile strong or weak? CN-

Which of the following is a reasonable definition of a concerted reaction?

What is the mechanism for the following reaction?

For the following reaction,draw the product.

How would you accomplish the following transformation?

Is the following nucleophile strong or weak? H2S

Given the following rate law,what will happen to the rate if the concentration of MeI is doubled and the concentration of Me3N is halved? Rate = k[Me3N][MeI]

Provide an example of a strong nucleophile.

Which reagents would you use for the following reaction?

Is the following nucleophile strong or weak? HO-

Rank the following substrates from most to least reactive in an SN1 reaction.

What set of reaction conditions should favor an SN2 reaction on 2-bromo-3-methylbutane?

Rank the following substrates from most to least reactive in an SN2 reaction.

What is the product of the following reaction.Include stereochemistry.

Rank the following substrates from most to least reactive in an SN2 reaction.

From the given starting material,how could you stereospecifically form the given product?

What reaction mechanism is most likely for substitution on the following compound?

Which reagents would you use for the following reaction?

A Review of General Chemistry: Electrons, Bonds, and Molecular Properties

Molecular Representations

Acids and Bases

Alkanes and Cycloalkanes

Stereoisomerism

Chemical Reactivity and Mechanisms

Alkenes: Structure and Preparation Via Elimination Reactions

Addition Reactions of Alkenes

Alkynes

Radical Reactions

Synthesis

Alcohols and Phenols

Ethers and Epoxides; Thiols and Sulfides

Nuclear Magnetic Resonance Spectroscopy

Infrared Spectroscopy and Mass Spectrometry

Conjugated Pi Systems and Pericyclic Reactions

Aromatic Compounds

Aromatic Substitution Reactions

Aldehydes and Ketones

Carboxylic Acids and Their Derivatives

Alpha Carbon Chemistry: Enols and Enolates

Amines

Carbohydrates

Amino Acids, Peptides, and Proteins

Lipids

Synthetic Polymers

Filters

Draw a reaction diagram for the following S_N1 reaction.

Is the following nucleophile strong or weak? CN^-

Is the following nucleophile strong or weak? H₂S

Given the following rate law,what will happen to the rate if the concentration of MeI is doubled and the concentration of Me₃N is halved? Rate = k[Me₃N][MeI]

Is the following nucleophile strong or weak? HO^-

Rank the following substrates from most to least reactive in an S_N1 reaction.

What set of reaction conditions should favor an S_N2 reaction on 2-bromo-3-methylbutane?

Rank the following substrates from most to least reactive in an S_N2 reaction.

Rank the following substrates from most to least reactive in an S_N2 reaction.