Question 1

Provide an example of gene redundancy that occurs in both eukaryotes and prokaryotes.

Accepted Answer

rDNA

Question 2

An autotriploid may arise when three sperm cells are involved in fertilization of a single egg.

Accepted Answer

A) True 
 B)False  False

Question 3

A paracentric inversion is one whose breakpoints do not flank the centromere.

Accepted Answer

A) True 
 B)False  True

Question 4

Assume that a species has a diploid chromosome number of 24. The term applied to an individual with 25 chromosomes would be triploid.

Accepted Answer

A) True 
 B)False

Question 5

Inversions and translocations are without evolutionary significance.

Accepted Answer

A) True 
 B)False

Question 6

rDNA in eukaryotes is typically redundant.

Accepted Answer

A) True 
 B)False

Question 7

Colchicine is an alkaloid derived from plants. What is its effect on chromosome behavior?

Accepted Answer

By interfering with spindle fo

Question 8

What is meant by the terms acentric and dicentric?

Accepted Answer

A chromosome without

Question 9

The condition known as cri-du-chat syndrome in humans has a genetic constitution designated as ________.

Accepted Answer

A)  45, X 
B)  heteroplasmy 
C)  46, 5p- 
D)  triploidy 
E)  trisomy 
A)  45, X 
B)  heteroplasmy 
C)  46, 5p- 
D)  triploidy 
E)  trisomy

Question 10

Gene duplications provide an explanation for the origin of gene families.

Accepted Answer

A) True 
 B)False

Question 11

Name two methods used in genetic prenatal diagnostic testing in humans.

Accepted Answer

amniocente

Question 12

Under what circumstance can an individual with Down syndrome have 46 chromosomes?

Accepted Answer

if he or she carries

Question 13

Recently, a gene located on chromosome 3 in humans, FHIT, has been shown to be associated with the significant human malady known as ________.

Accepted Answer

A)  cancer 
B)  Huntington disease 
C)  "mad-cow" disease 
D)  Klinefelter syndrome 
E)  XYY/XY mosaicism 
A)  cancer 
B)  Huntington disease 
C)  "mad-cow" disease 
D)  Klinefelter syndrome 
E)  XYY/XY mosaicism

Question 14

Inversions suppress crossing over by providing a chemical imbalance because of breakpoints within certain genes.

Accepted Answer

A) True 
 B)False

Question 15

Nondisjunction is viewed as a major cause of aneuploidy.

Accepted Answer

A) True 
 B)False

Question 16

An expected meiotic pairing configuration in a triploid would be a trivalent.

Accepted Answer

A) True 
 B)False

Question 17

Trisomy 21, or Down syndrome, occurs when there is a normal diploid chromosomal complement but one (extra) chromosome 21. Although fertility is reduced in both sexes, females have higher fertility rates than males. Van Dyke et al. (1995; Down Syndrome Research and Practice 3(2): 65-69) summarize data involving children born of Down syndrome individuals. Assume that children are born to a female with Down syndrome and a normal 46-chromosome male. What proportion of the offspring would be expected to have Down syndrome?

Accepted Answer

A)  One-third of the offspring would be expected to have Down syndrome. 
B)  Two-thirds of the offspring would be expected to have Down syndrome. 
C)  All the children would be expected to have Down syndrome. 
D)  None of the offspring would be expected to have Down syndrome. 
E)  One-half of the offspring would be expected to have Down syndrome. 
A)  One-third of the offspring would be expected to have Down syndrome. 
B)  Two-thirds of the offspring would be expected to have Down syndrome. 
C)  All the children would be expected to have Down syndrome. 
D)  None of the offspring would be expected to have Down syndrome. 
E)  One-half of the offspring would be expected to have Down syndrome.

Question 18

Name the polyploid condition that is formed from the addition of an extra set of chromosomes identical to the normal diploid complement of the same species.

Accepted Answer

autotetraploidy, ass

Question 19

Doubling the chromosomes of a sterile species hybrid with colchicine or cold shock is a method used to produce a fertile species hybrid (amphidiploid).

Accepted Answer

A) True 
 B)False

Question 20

Chorionic villus sampling (CVS) is sometimes preferred to amniocentesis because results can be provided earlier in the pregnancy.

Accepted Answer

A) True 
 B)False

Exam 8: Chromosome Mutations: Variation in Number and Arrangement

Provide an example of gene redundancy that occurs in both eukaryotes and prokaryotes.

An autotriploid may arise when three sperm cells are involved in fertilization of a single egg.

A paracentric inversion is one whose breakpoints do not flank the centromere.

Assume that a species has a diploid chromosome number of 24. The term applied to an individual with 25 chromosomes would be triploid.

Inversions and translocations are without evolutionary significance.

rDNA in eukaryotes is typically redundant.

Colchicine is an alkaloid derived from plants. What is its effect on chromosome behavior?

What is meant by the terms acentric and dicentric?

The condition known as cri-du-chat syndrome in humans has a genetic constitution designated as ________.

Gene duplications provide an explanation for the origin of gene families.

Name two methods used in genetic prenatal diagnostic testing in humans.

Under what circumstance can an individual with Down syndrome have 46 chromosomes?

Recently, a gene located on chromosome 3 in humans, FHIT, has been shown to be associated with the significant human malady known as ________.

Inversions suppress crossing over by providing a chemical imbalance because of breakpoints within certain genes.

Nondisjunction is viewed as a major cause of aneuploidy.

An expected meiotic pairing configuration in a triploid would be a trivalent.

Name the polyploid condition that is formed from the addition of an extra set of chromosomes identical to the normal diploid complement of the same species.

Doubling the chromosomes of a sterile species hybrid with colchicine or cold shock is a method used to produce a fertile species hybrid (amphidiploid).

Chorionic villus sampling (CVS) is sometimes preferred to amniocentesis because results can be provided earlier in the pregnancy.

Introduction to Genetics

Mitosis and Meiosis

Mendelian Genetics

Extensions of Mendelian Genetics

Chromosome Mapping in Eukaryotes

Genetic Analysis and Mapping in Bacteria and Bacteriophages

Sex Determination and Sex Chromosomes

Extranuclear Inheritance

DNA Structure and Analysis

DNA Replication and Recombination

DNA Organization in Chromosomes

The Genetic Code and Transcription

Translation and Proteins

Gene Mutation, Dna Repair, and Transposition

Regulation of Gene Expression in Prokaryotes

Regulation of Gene Expression in Eukaryotes

Developmental Genetics

Cancer and Regulation of the Cell Cycle

Recombinant Dna Technology

Genomics, Bioinformatics, and Proteomics

Applications and Ethics of Genetic Engineering and Biotechnology

Quantitative Genetics and Multifactorial Traits

Neurogenetics

Population and Evolutionary Genetics

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