Exam 5: Extensions and Modifications of Basic Principles
Exam 1: Introduction to Genetics65 Questions
Exam 2: Chromosomes and Cellular Reproduction62 Questions
Exam 3: Basic Principles of Heredity65 Questions
Exam 4: Sex Determination and Sex-Linked Characteristics87 Questions
Exam 5: Extensions and Modifications of Basic Principles93 Questions
Exam 6: Pedigree Analysis, Applications, and Genetic Testing78 Questions
Exam 7: Linkage, Recombination, and Eukaryotic Gene Mapping65 Questions
Exam 8: Chromosome Variation68 Questions
Exam 9: Bacterial and Viral Genetic Systems71 Questions
Exam 10: DNA: the Chemical Nature of the Gene82 Questions
Exam 11: Chromosome Structure and Organelle Dna83 Questions
Exam 12: DNA Replication and Recombination61 Questions
Exam 13: Transcription80 Questions
Exam 14: Rna Molecules and Rna Processing75 Questions
Exam 15: The Genetic Code and Translation76 Questions
Exam 16: Control of Gene Expression in Prokaryotes68 Questions
Exam 17: Control of Gene Expression in Eukaryotes64 Questions
Exam 18: Gene Mutations and Dna Repair100 Questions
Exam 19: Molecular Genetic Analysis and Biotechnology72 Questions
Exam 20: Genomics and Proteomics79 Questions
Exam 21: Epigenetics55 Questions
Exam 22: Developmental Genetics and Immunogenetics63 Questions
Exam 23: Cancer Genetics74 Questions
Exam 24: Quantitative Genetics81 Questions
Exam 25: Population Genetics69 Questions
Exam 26: Evolutionary Genetics63 Questions
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In domestic chickens, some males display a plumage pattern called cock feathering. Other males and all females display a pattern called hen feathering. Cock feathering is an autosomal recessive trait that is exhibited in males only.
- Two heterozygous birds are mated. What fraction of the total offspring is expected to exhibit cock feathering?
(Multiple Choice)
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The himalayan allele in rabbits produces dark fur at the extremities of the body-on the nose, ears, and feet. The dark pigment develops, however, only when a rabbit is reared at a temperature of 25°C or lower; if a Himalayan rabbit is reared at 30°C, no dark patches develop. What does this exemplify?
(Multiple Choice)
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A mother of blood type A gives birth to a child with blood type O. Which of the following could NOT be the blood type of the father?
(Multiple Choice)
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Crossing two yellow mice results in 2/3 yellow offspring and 1/3 nonyellow offspring. What percentage of offspring would you expect to be nonyellow if you crossed two nonyellow mice?
(Multiple Choice)
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You observe continuous variation in tail length in a wild population of rats. How would you determine whether this variation is an example of variable expressivity or polygenic inheritance?
(Essay)
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Coat color is determined by two loci in large cats. Two pink panthers fall in love and produce a large litter of baby panthers with the following phenotypic ratios: 12/16 pink; 3/16 black; and 1/16 white.
-What kind of gene interaction is this?
(Multiple Choice)
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In rabbits, an allelic series helps to determine coat color: C (full color), cch (chinchilla; gray color), ch (Himalayan; white with black extremities), and c (albino; all white). The C allele is dominant to all others, cch is dominant to ch and c, ch is dominant to c, and c is recessive to all the other alleles. This dominance hierarchy can be summarized as C > cch > ch > c.
-Indicate the phenotypic ratios expected of rabbits with the cross Cc × chc.
(Multiple Choice)
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The bicoid mutation (bcd-) in fruit flies is inherited as a maternal effect recessive allele. What is the expected ratio of phenotypes in the offspring of a cross between a bcd+/bcd- female and a bcd+/bcd- male?
(Multiple Choice)
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Assume that a human gene is imprinted. Normal individuals have one active copy of the gene, the copy inherited from their fathers. The copy inherited from their mothers is normally inactive.
In one large family a mutation in this gene occurs and this mutation results in part of the gene being deleted. The defective gene is never active regardless of the parent from which it is inherited. Individuals who carry the mutation are heterozygous and also have a normal copy of the gene whose activity depends upon which parent it was inherited from. Individuals who have no active copy of the gene have several medical problems but live long enough to have children of their own. This family includes two phenotypically normal parents who have two affected children, a son and a daughter. Which parent, father or mother, did the affected children inherit this mutation from? Why?
(Short Answer)
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In domestic chickens, some males display a plumage pattern called cock feathering. Other males and all females display a pattern called hen feathering. Cock feathering is an autosomal recessive trait that is exhibited in males only.
- Two heterozygous birds are mated. What fraction of the female offspring is expected to exhibit cock feathering?
(Multiple Choice)
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In chickens, comb shape is determined by genes at two loci (R, r and P, p). A walnut comb is produced when at least one dominant gene R is present at one locus and at least one dominant gene P is present at a second locus (genotype R_ P_). A rose comb is produced when at least one dominant gene is present at the first locus and two recessive genes are present at the second locus (genotype R_ pp). A pea comb is produced when two recessive genes are present at the first locus and at least one dominant gene is present at the second (genotype rr P_). If two recessive genes are present at the first and the second locus (rr pp), a single comb is produced.
- Give genotypes for comb shape of the parents in the following cross: Rose crossed with single produces 10 rose and 11 single offspring.
(Multiple Choice)
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In the endangered African watchamakallit, the offspring of a true-breeding black parent and a true-breeding white parent are all gray. When the gray offspring are crossed among themselves, their offspring occur in a ratio of 1 black : 2 gray : 1 white. Upon close examination of the coats, each hair of a gray animal is gray. What is the mode of inheritance?
(Multiple Choice)
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Polydactyly is the condition of having extra fingers or toes. Some polydactylous persons possess extra fingers or toes that are fully functional, whereas others possess only a small tag of extra skin. This is an example of:
(Multiple Choice)
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You are studying a gene that controls ossicone (horn) length in giraffes. The wild-type long-ossicone allele (L) is dominant to the mutant short-ossicone (l) allele. However, the L allele is only 60% penetrant. You cross two heterozygous giraffes. What proportion of offspring would you expect to exhibit the short-ossicone phenotype? Assume the penetrance of L applies equally to both homozygotes and heterozygotes.
(Multiple Choice)
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Explain the differences between incomplete dominance and continuous variation.
(Essay)
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In humans, blood types A and B are codominant to each other and each is dominant to O. What blood types are possible among the offspring of a couple of blood types AB and A?
(Multiple Choice)
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In chickens, comb shape is determined by genes at two loci (R, r and P, p). A walnut comb is produced when at least one dominant gene R is present at one locus and at least one dominant gene P is present at a second locus (genotype R_ P_). A rose comb is produced when at least one dominant gene is present at the first locus and two recessive genes are present at the second locus (genotype R_ pp). A pea comb is produced when two recessive genes are present at the first locus and at least one dominant gene is present at the second (genotype rr P_). If two recessive genes are present at the first and the second locus (rr pp), a single comb is produced.
-Give genotypes for comb shape of the parents in the following cross: Rose crossed with walnut produces 6 walnut, 6 rose, 2 single, and 2 pea offspring.
(Multiple Choice)
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Two mice of the same species have different ear shapes. You find that one mouse, having ears of normal shape, was caught in a field in Kenya. The other mouse, with curled ears, was caught in the frozen tundra of Greenland. You have determined that both mice have identical genotypes at the gene loci controlling ear shape. How would you explain the differences in ear shape?
(Short Answer)
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