Exam 20: Microbial Diseases of the Nervous System and Eyes

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Naturally-occurring poliomyelitis has occurred as recently as 2007 in the Americas.

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The pleomorphic bacterium is an obligate parasite due to its requirement for NAD + and heme.

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The condition called (conjunctivitis/keratitis/trachoma) is the result of infection of the cornea.

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Negri bodies are a characteristic microscopic finding in the diagnosis of (encephalitis/leprosy/rabies).

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Poliovirus is most often transmitted via

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The neurotoxins of Clostridium botulinum produce (paralysis/spasms/weakness) by interfering with acetylcholine secretion.

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The Gram-negative diplococcus is resistant to phagocytosis and releases Lipid A to cause inflammation.

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When a strong T cell immune response against Mycobacterium leprae fails to develop, (lepromatous/tuberculoid) leprosy results.

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A one-year-old child is brought to the hospital with high fever and limited range of motion of the head. The child frequently rubs her head. A recent history is not immediately available due to a language barrier on the part of the parent. The attending physician suspects meningitis and orders a sample of CFS be collected. Describe the various diagnoses possible based on the results with the CSF.

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Botulism toxin disrupts motor control by

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Discuss the two types of poliovirus vaccines available, including the advantages and disadvantages of each.

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A child is brought to the hospital with a high fever, nausea, and vomiting, and complaining of headache. The cerebrospinal fluid collected by spinal tap is cloudy and contains spherical cells which stain Gram-positive. These signs and symptoms are consistent with

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Functions of the meninges include

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Which of the following diseases is the result of a bacterial infection of peripheral nerves?

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Newborns exposed to the Gram-positive bacterium during vaginal birth are at risk of developing neonatal meningitis.

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The presence of (cocci/diplococci/coccobacilli/streptococci) in the CSF is consistent with infection with Listeria monocytogenes. (Describe the appearance of the cells.)

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Slow deterioration of muscle function occurring over many years occurs in

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A baby arrives at an emergency room suffering from violent muscles spasms and difficulty breathing. The babyʹs body is so rigid a proper exam is difficult, but the staff note the baby is only a few weeks old and the umbilicus has not healed properly. The signs are consistent with which of the following diseases?

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Contaminated food is the source of , which causes meningitis in the elderly and susceptible persons.

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Which of the following nervous system diseases is treated with both passive and active immunization?

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