Exam 15: Microbial Mechanisms of Pathogenicity

Patients developed inflammation a few hours following eye surgery. Instruments and solutions were sterile, and the Limulus assay was positive. The patientsʹ inflammation was due to

Most pathogens that gain access through the skin

Table 15.1 Bacterium Portal of Entry ID 50 Stophylococcus aureus Wound <10 Stwohylococcus aureus Wound + Ampicillin 300 Table 15.1 shows the ID50 for Staphylococcus aureus in wounds with and without the administration of ampicillin before surgery. Based on the data, the administration of ampicillin before surgery

Botulism is caused by ingestion of a proteinaceous exotoxin; therefore, it can easily be prevented by

Antibiotics can lead to septic shock if used to treat

The M protein enhances the virulence of Streptococcus by preventing phagocytosis.

Infections with some viruses may induce chromosomal changes that alter the growth properties of host cells.

The most frequently used portal of entry for pathogens is the

Polio is transmitted by ingestion of water contaminated with feces containing polio virus. What portal of entry does polio virus use?

Which of the following cytopathic effects is cytocidal?

Cholera toxin polypeptide A binds to surface gangliosides on target cells. If the gangliosides were removed,

Many pathogens use the same portal for entry and exit from the body.

Superantigens produce intense immune responses by stimulating lymphocytes to produce

Which of the following is NOT a membrane-disrupting toxin?

All of the following are examples of entry via the parenteral route EXCEPT

Table 15.2 Bacterium ID50 E. coli 0157: 20 Legionella pneumophia 1 Shigella 10 Treponema pallidum 57 -Which organism in Table 15.2 causes the most severe disease?

Lysogenic bacteriophages contribute to bacterial virulence because bacteriophages

Gram-negative septic shock results from the following events. What is the second step?

Symptoms of intense inflammation and shock occur in some gram -positive bacterial infections due to

Which of the following is an example of direct damage due to bacterial infection?