Exam 1: Genetics of Bacteria and Bacteriophages

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Which method is least useful for assessing levels of genetic variation in populations?

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Heterozygotes for the sickle-cell allele show higher fitness than either homozygote genotype in malarial regions. This is an example of

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This chapter discussed speciation by genetic divergence following geographic isolation, which is expected to lead to reduced gene flow. This is known as allopatric speciation. A more controversial form of speciation is genetic divergence of populations without physical isolation; this is called sympatric speciation. Can you envision a mechanism or process that would permit two coexisting populations of the same species to begin to diverge without being isolated from one another?

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Sympatric speciation is thought to be uncommon but almost certainly has occurred. In one general scenario, a form of isolation "in place," or in sympatry, may occur if males or females begin (by drift, perhaps) to prefer different resources-say, a special site for mating or laying eggs. If their mates follow in this "imprinting" process, the two preference populations may begin to experience reduced gene flow between them, which if maintained long enough may bring about a degree of genetic divergence that would be selectively reinforced should some of the individuals from the two populations ever hybridize.

Show algebraically that under Hardy-Weinberg equilibrium, allele frequencies will not change from one generation to another.

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Which of the following populations would be expected to experience the greatest degree of genetic drift?

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In the early twentieth century, evolutionary biologists argued whether there was enough genetic variation in populations to explain the diversity of life by natural selection. With the advent of protein electrophoresis and DNA-level analysis, the problem turned on its head: the neutralist school arose from the idea that there was too much genetic variation to be maintained by natural selection. What are some of the arguments and observations neutralists cited to support the idea that much variation is neither favored nor disfavored by natural selection?

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The frequency of a recessive X-linked allele is equal to the phenotypic frequency of males exhibiting that allele.

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The deciduous forest of eastern North America experienced dramatic changes over the past two to three centuries, transitioning from a nearly continuous forested area to increasingly patchy forest broken up by farming and development. Some species are more sensitive to severe habitat fragmentation than others; what are some characteristics that might make a species more susceptible to the effects of habitat and population fragmentation?

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Observed genotypic frequencies in populations rarely match HW expectations exactly. Why is this so, and how can you determine if the frequencies you observe depart from HW in a biologically meaningful degree?

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The northern elephant seal, Mirounga angustirostris, suffered a significant population bottleneck in the late nineteenth century, when hunting reduced their population size to as few as 20 individuals. It has since rebounded to several tens of thousands. The related southern elephant seal, M. leonine, was not hunted as intensively. What prediction can you make about the relative levels of heterozygosity in populations of these two species?

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Survival is the single most important process in evolution by natural selection.

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What is the frequency of the a allele in the beetle population described in question 14?

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Mutation may be the ultimate source of genetic variation, but sexual reproduction and similar processes like bacterial conjugation or transformation are also important in continually generating novel genetic combinations.

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If the genotypic frequencies for an allele in an HW population are 0.635 homozygous dominants, 0.430 heterozygotes, and 0.125 homozygous recessives, what is the frequency of the recessive allele?

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________ is the ultimate source of genetic variation in populations.

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The Hardy-Weinberg relationship cannot be used to compute allele frequencies when one or more alleles are recessive.

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For which trait is human mating expected to be nonrandom?

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In the Hardy-Weinberg model, the ideal population is

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The population mean for a given measured trait is observed to decline over the course of several generations. This is an example of disruptive selection.

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Two neighboring Caribbean islands harbor iguana populations. One island (island

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