Question 1

In eukaryotes, precursor mRNA molecules are processed in the

Accepted Answer

A)  mitochondria. 
B)  ribosomes. 
C)  nucleus. 
D)  cytoplasm. 
E)  nucleolus. 
A)  mitochondria. 
B)  ribosomes. 
C)  nucleus. 
D)  cytoplasm. 
E)  nucleolus. C

Question 2

In eukaryotes, where does transcription take place?

Accepted Answer

A)  Anywhere in the cell 
B)  In the nucleus 
C)  In both the cytoplasm and nucleus 
D)  In the mitochondrion 
E)  In the cytoplasm 
A)  Anywhere in the cell 
B)  In the nucleus 
C)  In both the cytoplasm and nucleus 
D)  In the mitochondrion 
E)  In the cytoplasm B

Question 3

Prokaryotic transcription begins when RNA polymerase binds to which site of the gene region?

Accepted Answer

A)  -35 
B)  +35 
C)  -10 
D)  +1 
E)  +10 
A)  -35 
B)  +35 
C)  -10 
D)  +1 
E)  +10 D

Question 4

Unlike eukaryotic mRNA, prokaryotic mRNA is polycistronic.

Accepted Answer

A) True 
 B)False

Question 5

Which type of RNA is found only in eukaryotes?

Accepted Answer

A)  snRNA 
B)  rRNA 
C)  mRNA 
D)  tRNA 
E)  All of the above 
A)  snRNA 
B)  rRNA 
C)  mRNA 
D)  tRNA 
E)  All of the above

Question 6

What are the three basic steps of transcription?

Accepted Answer

Initiation

Question 7

What was the significance of the 1978 finding by Philip Leder's research group that the 0.7 kb β-globin mRNA is not colinear with the gene that encodes it, but the nuclear 1.5 kb pre-mRNA is?

Accepted Answer

This meant that the β-globin contains an

Question 8

Self-cleaving RNAs that function catalytically are called

Accepted Answer

A)  snRNPs. 
B)  ribosomes. 
C)  ribozymes. 
D)  spliceosomes. 
E)  snRNAs. 
A)  snRNPs. 
B)  ribosomes. 
C)  ribozymes. 
D)  spliceosomes. 
E)  snRNAs.

Question 9

In eukaryotes, mature mRNAs typically have introns, a 5' cap, and a polyA tail.

Accepted Answer

A) True 
 B)False

Question 10

The process by which genetic information is transferred from DNA to RNA is called

Accepted Answer

A)  transversion. 
B)  translation. 
C)  transformation. 
D)  transcription. 
E)  replication. 
A)  transversion. 
B)  translation. 
C)  transformation. 
D)  transcription. 
E)  replication.

Question 11

RNA splicing takes place on ribosomes, which contain the pre-mRNA molecule and histones.

Accepted Answer

A) True 
 B)False

Question 12

During transcription, the synthesis of the mRNA strand proceeds in which direction?

Accepted Answer

A)  Both 5' to 3' and 3' to 5' 
B)  First 5' to 3', and then 3' to 5' 
C)  3' to 5' only 
D)  Either 5' to 3' or 3' to 5' 
E)  5' to 3' only 
A)  Both 5' to 3' and 3' to 5' 
B)  First 5' to 3', and then 3' to 5' 
C)  3' to 5' only 
D)  Either 5' to 3' or 3' to 5' 
E)  5' to 3' only

Question 13

Before a prokaryotic mRNA can be translated, it must be modified by the addition of a polyA tail.

Accepted Answer

A) True 
 B)False

Question 14

In eukaryotes, the initiation complex binds DNA at the

Accepted Answer

A)  CAAT box. 
B)  TATA box. 
C)  GTF region. 
D)  GC box. 
E)  Pribnow box. 
A)  CAAT box. 
B)  TATA box. 
C)  GTF region. 
D)  GC box. 
E)  Pribnow box.

Question 15

What is the advantage of having a promoter sequence upstream of a coding sequence?

Accepted Answer

The promoter ensures that the

Question 16

How does the rate of initiation of transcription relate to the similarity of the promoter region to the consensus sequence?

Accepted Answer

The ability of the sigma factor of the R

Question 17

Termination is carried out by RNA polymerase in a rho-independent terminator.

Accepted Answer

A) True 
 B)False

Question 18

What are the functions of the 5' cap and poly(A) tail of mature mRNAs in eukaryotes?

Accepted Answer

Both of them protect the mRNA from degra

Question 19

In eukaryotes, what is the difference between promoter proximal elements in "housekeeping genes" vs. cell-specific genes, and how does this relate to gene expression?

Accepted Answer

In genes that are expressed in all cell

Question 20

A promoter is a coding portion of a gene.

Accepted Answer

A) True 
 B)False

Exam 12: Genetic Analysis of Development

In eukaryotes, precursor mRNA molecules are processed in the

In eukaryotes, where does transcription take place?

Prokaryotic transcription begins when RNA polymerase binds to which site of the gene region?

Unlike eukaryotic mRNA, prokaryotic mRNA is polycistronic.

Which type of RNA is found only in eukaryotes?

What are the three basic steps of transcription?

What was the significance of the 1978 finding by Philip Leder's research group that the 0.7 kb β-globin mRNA is not colinear with the gene that encodes it, but the nuclear 1.5 kb pre-mRNA is?

Self-cleaving RNAs that function catalytically are called

In eukaryotes, mature mRNAs typically have introns, a 5' cap, and a polyA tail.

The process by which genetic information is transferred from DNA to RNA is called

RNA splicing takes place on ribosomes, which contain the pre-mRNA molecule and histones.

During transcription, the synthesis of the mRNA strand proceeds in which direction?

Before a prokaryotic mRNA can be translated, it must be modified by the addition of a polyA tail.

In eukaryotes, the initiation complex binds DNA at the

What is the advantage of having a promoter sequence upstream of a coding sequence?

How does the rate of initiation of transcription relate to the similarity of the promoter region to the consensus sequence?

Termination is carried out by RNA polymerase in a rho-independent terminator.

What are the functions of the 5' cap and poly(A) tail of mature mRNAs in eukaryotes?

In eukaryotes, what is the difference between promoter proximal elements in "housekeeping genes" vs. cell-specific genes, and how does this relate to gene expression?

A promoter is a coding portion of a gene.

Genetics of Bacteria and Bacteriophages

Variations in Chromosome Structure and Number

Advanced Gene Mapping in Eukaryotes

Gene Mapping in Eukaryotes

Quantitative Genetics

Extensions of Mendelian Genetic Principles

Chromosomal Basis of Inheritance

Molecular Evolution

Population Genetics

Non-Mendelian Inheritance

Genetics of Cancer

Regulation of Gene Expression in Eukaryotes

Mendelian Genetics

Regulation of Gene Expression in Bacteria and Bacteriophages

Genomics

Applications of Recombinant DNA Technology

Recombinant DNA Technology

DNA Mutation, DNA Repair, and Transposable Elements

Gene Expression: Translation

Gene Expression: Transcription

Gene Control of Proteins

DNA Replication

DNA: The Genetic Material

Genetics: an Introduction

Filters