Question 1

Cytotoxic T lymphocytes insert (CD95/lectin/perforin) into the membranes of the cells they target as a first step in killing.

Accepted Answer

perforin

Question 2

IgG antibodies can carry out all five antibody functions.

Accepted Answer

A) True 
 B)False  True

Question 3

The third line of defense is called (adaptive/clonal/self-tolerant) because it does not normally respond to autoantigens.

Accepted Answer

self-tolerant

Question 4

Which of the following is the result when a CTL interacts with a virally infected cell?

Accepted Answer

A)  The cell releases interferon-gamma (INF-γ). 
B)  The cell undergoes apoptosis. 
C)  The CTL produces oxidizing chemicals. 
D)  The CTL produces IL-12. 
E)  The cell produces MHC II with epitope attached. 
A)  The cell releases interferon-gamma (INF-γ). 
B)  The cell undergoes apoptosis. 
C)  The CTL produces oxidizing chemicals. 
D)  The CTL produces IL-12. 
E)  The cell produces MHC II with epitope attached.

Question 5

Which of the following statements concerning the chemical structure of an antibody is FALSE?

Accepted Answer

A)  Antibodies are formed of four polypeptide chains. 
B)  Antibodies have two long peptide chains known as heavy chains. 
C)  Antibodies have two short peptide chains known as light chains. 
D)  The stem and arm are connected by a hinge. 
E)  The heavy and light chains are connected by hydrogen bonds. 
A)  Antibodies are formed of four polypeptide chains. 
B)  Antibodies have two long peptide chains known as heavy chains. 
C)  Antibodies have two short peptide chains known as light chains. 
D)  The stem and arm are connected by a hinge. 
E)  The heavy and light chains are connected by hydrogen bonds.

Question 6

Which of the following statements about lymphocytes is FALSE?

Accepted Answer

A)  Once they are mature, they migrate to secondary lymphoid organs. 
B)  B and T lymphocytes can be differentiated using a bright-field light microscope. 
C)  Lymphocytes have integral surface proteins by which they can be recognized. 
D)  The glycoproteins on the surface of a lymphocyte are designated with the prefix CD, for "cluster of differentiation." 
E)  Lymphocytes have different types of CD molecules in their cytoplasmic membranes. 
A)  Once they are mature, they migrate to secondary lymphoid organs. 
B)  B and T lymphocytes can be differentiated using a bright-field light microscope. 
C)  Lymphocytes have integral surface proteins by which they can be recognized. 
D)  The glycoproteins on the surface of a lymphocyte are designated with the prefix CD, for "cluster of differentiation." 
E)  Lymphocytes have different types of CD molecules in their cytoplasmic membranes.

Question 7

Which of the following function in agglutination?

Accepted Answer

A)  IgA antibodies 
B)  IgG antibodies 
C)  IgE antibodies 
D)  IgD antibodies 
E)  IgA and IgG antibodies 
A)  IgA antibodies 
B)  IgG antibodies 
C)  IgE antibodies 
D)  IgD antibodies 
E)  IgA and IgG antibodies

Question 8

Secretory IgA antibodies are unique because they

Accepted Answer

A)  have unique light chains. 
B)  are Y-shaped molecules. 
C)  are present in the plasma. 
D)  are connected with J chains and short polypeptides to form dimers. 
E)  are present in lymph nodes. 
A)  have unique light chains. 
B)  are Y-shaped molecules. 
C)  are present in the plasma. 
D)  are connected with J chains and short polypeptides to form dimers. 
E)  are present in lymph nodes.

Question 9

T lymphocytes mature in the (bone marrow/lymph node/thymus).

Accepted Answer

The answer of T lymphocytes mature in the (bone marrow/lymph...

Question 10

Compare and contrast clonal deletion and clonal selection of B lymphocytes.

Accepted Answer

Both clonal deletion and clonal selectio

Question 11

Which of the following statements regarding antibody function is FALSE?

Accepted Answer

A)  They can prevent virus attachment to host cells. 
B)  They can facilitate phagocyte attack on bacteria with a capsule (glycocalyx). 
C)  They can penetrate host cells to bind intracellular antigens. 
D)  They can facilitate cytotoxic attack by natural killer lymphocytes. 
E)  They can bind more than one pathogen at a time, forming complexes. 
A)  They can prevent virus attachment to host cells. 
B)  They can facilitate phagocyte attack on bacteria with a capsule (glycocalyx). 
C)  They can penetrate host cells to bind intracellular antigens. 
D)  They can facilitate cytotoxic attack by natural killer lymphocytes. 
E)  They can bind more than one pathogen at a time, forming complexes.

Question 12

A variety of molecular components of the adaptive immune system bind epitopes (antigenic determinants). Compare and contrast the binding of epitopes by antibody molecules, T cell receptors (TCRs), and MHC molecules, and describe the consequences of the different interactions.

Accepted Answer

MHC molecules bind processed antigen for

Question 13

The immunologic (agglutination/complex/synapse) forms when MHC molecules and TCR molecules connect.

Accepted Answer

The answer of The immunologic (agglutination/complex/synapse) forms when MHC molecules...

Question 14

The surface of each B lymphocyte is covered with about 250,000 to 500,000 identical copies of (BCR/MHC/TCR).

Accepted Answer

The answer of The surface of each B lymphocyte is...

Question 15

During an infection with Listeria, an intracellular bacterium, APCs will present antigen on MHC II molecules.

Accepted Answer

A) True 
 B)False

Question 16

The antibody function known as (agglutination/neutralization/opsonization) is illustrated in Figure 16.3.

Accepted Answer

The answer of   
The antibody function known as...

Question 17

Which of the following is true of chemokines?

Accepted Answer

A)  They ensure production of enough leukocytes. 
B)  They are involved in B lymphocyte activation and differentiation. 
C)  They are chemotactic factors for leukocytes. 
D)  They cause basophils and eosinophils to degranulate. 
E)  They are substances used to signal between leukocytes. 
A)  They ensure production of enough leukocytes. 
B)  They are involved in B lymphocyte activation and differentiation. 
C)  They are chemotactic factors for leukocytes. 
D)  They cause basophils and eosinophils to degranulate. 
E)  They are substances used to signal between leukocytes.

Question 18

Exogenous antigens are processed for immune recognition by ________ cells.

Accepted Answer

A)  dendritic 
B)  all nucleated 
C)  macrophage 
D)  helper T 
E)  dendritic and macrophage 
A)  dendritic 
B)  all nucleated 
C)  macrophage 
D)  helper T 
E)  dendritic and macrophage

Question 19

Cell-mediated immunity is a function of

Accepted Answer

A)  NK cells. 
B)  T lymphocytes. 
C)  B lymphocytes. 
D)  dendritic cells. 
E)  macrophages. 
A)  NK cells. 
B)  T lymphocytes. 
C)  B lymphocytes. 
D)  dendritic cells. 
E)  macrophages.

Question 20

Class I MHC molecules are essential for

Accepted Answer

A)  presentation of endogenous antigens. 
B)  recognition of chemokines. 
C)  detection of IL-2. 
D)  recognition of class II MHC. 
E)  presentation of exogenous antigens. 
A)  presentation of endogenous antigens. 
B)  recognition of chemokines. 
C)  detection of IL-2. 
D)  recognition of class II MHC. 
E)  presentation of exogenous antigens.

Exam 16: Adaptive Immunity

Cytotoxic T lymphocytes insert (CD95/lectin/perforin) into the membranes of the cells they target as a first step in killing.

IgG antibodies can carry out all five antibody functions.

The third line of defense is called (adaptive/clonal/self-tolerant) because it does not normally respond to autoantigens.

Which of the following is the result when a CTL interacts with a virally infected cell?

Which of the following statements concerning the chemical structure of an antibody is FALSE?

Which of the following statements about lymphocytes is FALSE?

Which of the following function in agglutination?

Secretory IgA antibodies are unique because they

T lymphocytes mature in the (bone marrow/lymph node/thymus).

Compare and contrast clonal deletion and clonal selection of B lymphocytes.

Which of the following statements regarding antibody function is FALSE?

A variety of molecular components of the adaptive immune system bind epitopes (antigenic determinants). Compare and contrast the binding of epitopes by antibody molecules, T cell receptors (TCRs), and MHC molecules, and describe the consequences of the different interactions.

The immunologic (agglutination/complex/synapse) forms when MHC molecules and TCR molecules connect.

The surface of each B lymphocyte is covered with about 250,000 to 500,000 identical copies of (BCR/MHC/TCR).

During an infection with Listeria, an intracellular bacterium, APCs will present antigen on MHC II molecules.

The antibody function known as (agglutination/neutralization/opsonization) is illustrated in Figure 16.3.

Which of the following is true of chemokines?

Exogenous antigens are processed for immune recognition by ________ cells.

Cell-mediated immunity is a function of

Class I MHC molecules are essential for

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